Mycn (MYCN) ELISA Kits

MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. Additionally we are shipping MYCN Antibodies (98) and MYCN Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MYCN 4613 P04198
MYCN 18109 P03966
MYCN 298894 Q63379
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Top MYCN ELISA Kits at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Rat 0.312-20 ng/mL   96 Tests Log in to see 2 to 3 Days
$779.90
Details
Rat
0.312-20 ng/mL   96 Tests Log in to see 15 to 18 Days
$946.00
Details
Mouse
  96 Tests Log in to see 15 to 18 Days
$946.00
Details
Chicken
  96 Tests Log in to see 15 to 18 Days
$1,095.60
Details

More ELISA Kits for MYCN Interaction Partners

Human Mycn (MYCN) interaction partners

  1. Results establish evidence that high MYCN amplification can be present in retinoblastoma with or without coding sequence mutations in the RB1 (show RB1 ELISA Kits) gene.

  2. USP7 (show USP7 ELISA Kits) deubiquitinates MYCN to enhance its stability and transcriptional activity in neuroblastoma (show ARHGEF16 ELISA Kits).

  3. The study conducted metabolic profiling of pre-malignant sympathetic ganglia and tumors derived from the TH-MYCN mouse model of neuroblastoma (show ARHGEF16 ELISA Kits), that overexpresses human MYCN and compared to non-malignant ganglia from wildtype littermates. These results identify enhanced glutathione biosynthesis as a selective metabolic adaptation required for initiation of MYCN-driven neuroblastoma (show ARHGEF16 ELISA Kits).

  4. Many prognostic signatures for neuroblastoma (show ARHGEF16 ELISA Kits) are confounded by MYCN amplification.

  5. Increasing MYCN copy number is associated with an increasingly higher rate of unfavorable clinical/biological features, with 11q aberration being an exception. Patients with MYCN gain appear to have inferior outcomes, especially in otherwise more favorable groups.

  6. miR (show MLXIP ELISA Kits)-21 enhances chemo-resistance in tongue cancer cells via directly targeting CADM1 (show CADM1 ELISA Kits), and an inverse correlation between miR (show MLXIP ELISA Kits)-21 and CADM1 (show CADM1 ELISA Kits) expression in vivo. MiR (show MLXIP ELISA Kits)-21 overexpression is attributed to MYCN-mediated transcriptional regulation, which is also predictive for a worse prognosis in tongue cancer

  7. LMO1 (show LMO1 ELISA Kits) is an important oncogene (show RAB1A ELISA Kits) that promotes neuroblastoma (show ARHGEF16 ELISA Kits) initiation, progression, and widespread metastatic dissemination.

  8. our results identify DOT1L (show DOT1L ELISA Kits) as a novel cofactor in N-Myc-mediated transcriptional activation of target genes and neuroblastoma (show ARHGEF16 ELISA Kits) oncogenesis. Furthermore, they characterize DOT1L (show DOT1L ELISA Kits) inhibitors as novel anticancer agents against MYCN-amplified neuroblastoma (show ARHGEF16 ELISA Kits).

  9. CCCTC-binding factor (CTCF (show CTCF ELISA Kits)) targets the binding sites within MYCN promoter to facilitate its expression in neuroblastoma (show ARHGEF16 ELISA Kits) (NB) cells.

  10. PAX3 (show PAX3 ELISA Kits)-FOXO1 (show FOXO1 ELISA Kits) collaborates with MYCN during early rhabdomyosarcoma (RMS) tumourigenesis to dysregulate proliferation and inhibit myogenic differentiation and cell death.

Mouse (Murine) Mycn (MYCN) interaction partners

  1. the role of N-myc in mouse lens development, was examined.

  2. Using comparative genomic hybridization, authors found that NCC (show SLC12A3 ELISA Kits)-derived NBL (show NUMBL ELISA Kits) tumors in mice acquired copy number gains and losses that are syntenic to those observed in human MYCN-amplified NBL (show NUMBL ELISA Kits) including 17q gain, 2p gain and loss of 1p36.

  3. a Mycn target gene encoding the miR (show MLXIP ELISA Kits) cluster miR-17~92, while most retinoblastomas reemerged without clear genetic alterations in either Mycn or known Mycn targets. This Rb/MYCN model recapitulates key genetic driver alterations seen in human retinoblastoma and reveals the emergence of MYCN independence in an initially MYCN-driven tumor.

  4. The findings reveal a PLK1 (show PLK1 ELISA Kits)-Fbw7 (show FBXW7 ELISA Kits)-Myc (show MYC ELISA Kits) signaling circuit that underlies tumorigenesis and validate PLK1 (show PLK1 ELISA Kits) inhibitors, alone or with Bcl2 (show BCL2 ELISA Kits) antagonists, as potential effective therapeutics for MYC (show MYC ELISA Kits)-overexpressing cancers.

  5. ALKR1275Q cooperated with MYCN in the development of aggressive NB, possibly by downregulating the expression of ECM (show MMRN1 ELISA Kits)/BM-associated genes and by conferring malignant potentials to MYCN-expressing cells.

  6. Reuslts show that N-Myc overexpression leads to the development of poorly differentiated, invasive prostate cancer that is molecularly similar to human NEPC.

  7. Thus, this synergistic effect of ZD55-shMYCN in combination with doxorubicin provides a novel therapy strategy for doxorubicin-resistant neuroblastoma (show ARHGEF16 ELISA Kits), and is a promising approach for further clinical development.

  8. demonstrate a critical link between Myc (show MYC ELISA Kits)/Mycn gene activity and glycolysis in spermatogonial stem cell self-renewal

  9. Loss of N-myc significantly impairs the Sonic hedgehog (show SHH ELISA Kits) signaling pathway and disrupts the expression of cell cycle effectors with a significant reduction of Ccnd2 (show CCND2 ELISA Kits).

  10. Study shows that ground-state embryonic stem cells express low Myc (show MYC ELISA Kits) levels. Deletion of both c-myc (show MYC ELISA Kits) and N-myc activity strongly decreases transcription, splicing, and protein synthesis, leading to proliferation arrest; process is reversible and occurs without affecting pluripotency, suggesting that Myc (show MYC ELISA Kits)-depleted stem cells enter a state of dormancy.

MYCN Antigen Profile

Antigen Summary

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas.

Gene names and symbols associated with Mycn (MYCN) ELISA Kits

  • MYCN proto-oncogene, bHLH transcription factor (MYCN) antibody
  • v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (MYCN) antibody
  • v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (Mycn) antibody
  • MYCN proto-oncogene, bHLH transcription factor (Mycn) antibody
  • olfactory receptor 8S1 (LOC515887) antibody
  • MYCN proto-oncogene, bHLH transcription factor (mycn) antibody
  • MYCN proto-oncogene, bHLH transcription factor S homeolog (mycn.S) antibody
  • bHLHe37 antibody
  • c-nmyc antibody
  • fb57a02 antibody
  • MODED antibody
  • mycn antibody
  • mycn-a antibody
  • mycn-b antibody
  • mycna antibody
  • MYCNOT antibody
  • N-myc antibody
  • Nmuc1 antibody
  • Nmyc antibody
  • Nmyc-1 antibody
  • nmyc1 antibody
  • ODED antibody
  • wu:fb57a02 antibody
  • XN-myc antibody
  • xN-myc1 antibody
  • XNmyc antibody
  • zgc:85706 antibody

Protein level used designations for Mycn (MYCN) ELISA Kits

N-myc proto-oncogene protein , class E basic helix-loop-helix protein 37 , neuroblastoma MYC oncogene , neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene , oncogene NMYC , pp65/67 , v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived , v-myc myelocytomatosis viral related oncogene, neuroblastoma derived , N-myc protein , neuroblastoma myc-related oncogene 1 , Avian myelocytomatosis viral (v-myc) related oncogene neuroblastoma derived (Nmyc) , Avian myelocytomatosis viral (v-myc) related oncogene, neuroblastoma derived (Nmyc) , N-myc-like protein , v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog , MYCN proto-oncogene, bHLH transcription factor S homeolog , v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog S homeolog , v-myc myelocytomatosis viral related oncogene, neuroblastoma derived, a

GENE ID SPECIES
4613 Homo sapiens
482978 Canis lupus familiaris
421948 Gallus gallus
18109 Mus musculus
298894 Rattus norvegicus
515887 Bos taurus
252851 Danio rerio
380041 Xenopus laevis
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