Mycn (MYCN) ELISA Kits

MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. Additionally we are shipping MYCN Antibodies (96) and MYCN Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MYCN 4613 P04198
MYCN 298894 Q63379
MYCN 18109 P03966
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Top MYCN ELISA Kits at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Rat 0.312-20 ng/mL   96 Tests Log in to see 2 to 3 Days
$724.90
Details
Rat
0.312-20 ng/mL   96 Tests Log in to see 15 to 18 Days
$946.00
Details
Mouse
  96 Tests Log in to see 15 to 18 Days
$946.00
Details
Chicken
  96 Tests Log in to see 15 to 18 Days
$1,095.60
Details

More ELISA Kits for MYCN Interaction Partners

Human Mycn (MYCN) interaction partners

  1. our results identify DOT1L (show DOT1L ELISA Kits) as a novel cofactor in N-Myc-mediated transcriptional activation of target genes and neuroblastoma (show ARHGEF16 ELISA Kits) oncogenesis. Furthermore, they characterize DOT1L (show DOT1L ELISA Kits) inhibitors as novel anticancer agents against MYCN-amplified neuroblastoma (show ARHGEF16 ELISA Kits).

  2. CCCTC-binding factor (CTCF (show CTCF ELISA Kits)) targets the binding sites within MYCN promoter to facilitate its expression in neuroblastoma (show ARHGEF16 ELISA Kits) (NB) cells.

  3. PAX3 (show PAX3 ELISA Kits)-FOXO1 (show FOXO1 ELISA Kits) collaborates with MYCN during early rhabdomyosarcoma (RMS) tumourigenesis to dysregulate proliferation and inhibit myogenic differentiation and cell death.

  4. The findings reveal a PLK1 (show PLK1 ELISA Kits)-Fbw7 (show FBXW7 ELISA Kits)-Myc (show MYC ELISA Kits) signaling circuit that underlies tumorigenesis and validate PLK1 (show PLK1 ELISA Kits) inhibitors, alone or with Bcl2 (show BCL2 ELISA Kits) antagonists, as potential effective therapeutics for MYC (show MYC ELISA Kits)-overexpressing cancers.

  5. Results show that N-Myc overexpression leads to the development of poorly differentiated, invasive prostate cancer that is molecularly similar to human NEPC.

  6. Rac (show AKT1 ELISA Kits) activity may be an important determinant of metastatic capability in subsets of neuroblastoma (show ARHGEF16 ELISA Kits) cells lacking MYCN amplification.

  7. MYCN Gene Amplification is associated with Neuroblastoma (show ARHGEF16 ELISA Kits).

  8. MYCN overexpression combined with activated anaplastic lymphoma kinase (ALK (show ALK ELISA Kits)) is sufficient to induce neuroblastoma (show ARHGEF16 ELISA Kits) (NB) in mouse sympathoadrenal cells

  9. MYCN amplification can be heterogeneous between tumor sites, during tumor progression or following treatment, challenging the notion that MYCN copy number does not change for a particular neuroblastoma (show ARHGEF16 ELISA Kits).

  10. High MycN expression is associated with low radiosensitivity in neuroblastoma (show ARHGEF16 ELISA Kits).

Mouse (Murine) Mycn (MYCN) interaction partners

  1. a Mycn target gene encoding the miR (show MLXIP ELISA Kits) cluster miR-17~92, while most retinoblastomas reemerged without clear genetic alterations in either Mycn or known Mycn targets. This Rb/MYCN model recapitulates key genetic driver alterations seen in human retinoblastoma and reveals the emergence of MYCN independence in an initially MYCN-driven tumor.

  2. The findings reveal a PLK1 (show PLK1 ELISA Kits)-Fbw7 (show FBXW7 ELISA Kits)-Myc (show MYC ELISA Kits) signaling circuit that underlies tumorigenesis and validate PLK1 (show PLK1 ELISA Kits) inhibitors, alone or with Bcl2 (show BCL2 ELISA Kits) antagonists, as potential effective therapeutics for MYC (show MYC ELISA Kits)-overexpressing cancers.

  3. ALKR1275Q cooperated with MYCN in the development of aggressive NB, possibly by downregulating the expression of ECM (show MMRN1 ELISA Kits)/BM-associated genes and by conferring malignant potentials to MYCN-expressing cells.

  4. Reuslts show that N-Myc overexpression leads to the development of poorly differentiated, invasive prostate cancer that is molecularly similar to human NEPC.

  5. Thus, this synergistic effect of ZD55-shMYCN in combination with doxorubicin provides a novel therapy strategy for doxorubicin-resistant neuroblastoma (show ARHGEF16 ELISA Kits), and is a promising approach for further clinical development.

  6. demonstrate a critical link between Myc (show MYC ELISA Kits)/Mycn gene activity and glycolysis in spermatogonial stem cell self-renewal

  7. Loss of N-myc significantly impairs the Sonic hedgehog (show SHH ELISA Kits) signaling pathway and disrupts the expression of cell cycle effectors with a significant reduction of Ccnd2 (show CCND2 ELISA Kits).

  8. Study shows that ground-state embryonic stem cells express low Myc (show MYC ELISA Kits) levels. Deletion of both c-myc (show MYC ELISA Kits) and N-myc activity strongly decreases transcription, splicing, and protein synthesis, leading to proliferation arrest; process is reversible and occurs without affecting pluripotency, suggesting that Myc (show MYC ELISA Kits)-depleted stem cells enter a state of dormancy.

  9. MYCN overexpression is not sufficient for these cells to form tumors in nude mice

  10. ITGA4 (show ITGA4 ELISA Kits) expression enhances metastasis in MYCN low neuroblastoma (show ARHGEF16 ELISA Kits).

MYCN Antigen Profile

Antigen Summary

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas.

Gene names and symbols associated with Mycn (MYCN) ELISA Kits

  • olfactory receptor, family 8, subfamily S, member 1-like (LOC515887) antibody
  • v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (MYCN) antibody
  • v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (Mycn) antibody
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (MYCN) antibody
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) (MYCN) antibody
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) (Mycn) antibody
  • bHLHe37 antibody
  • c-nmyc antibody
  • MODED antibody
  • MYCNOT antibody
  • N-myc antibody
  • Nmuc1 antibody
  • Nmyc antibody
  • Nmyc-1 antibody
  • Nmyc1 antibody
  • ODED antibody

Protein level used designations for Mycn (MYCN) ELISA Kits

N-myc proto-oncogene protein , class E basic helix-loop-helix protein 37 , neuroblastoma MYC oncogene , neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene , oncogene NMYC , pp65/67 , v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived , v-myc myelocytomatosis viral related oncogene, neuroblastoma derived , Avian myelocytomatosis viral (v-myc) related oncogene neuroblastoma derived (Nmyc) , Avian myelocytomatosis viral (v-myc) related oncogene, neuroblastoma derived (Nmyc) , N-myc protein , neuroblastoma myc-related oncogene 1

GENE ID SPECIES
515887 Bos taurus
4613 Homo sapiens
298894 Rattus norvegicus
421948 Gallus gallus
482978 Canis lupus familiaris
18109 Mus musculus
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