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anti-Myelin Basic Protein (MBP) Antibodies

The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. Additionally we are shipping Myelin Basic Protein Kits (48) and Myelin Basic Protein Proteins (31) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MBP 4155 P02686
MBP 24547 P02688
MBP 17196 P04370
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Top anti-Myelin Basic Protein Antibodies at antibodies-online.com

Showing 10 out of 197 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC (fro), IHC (p), WB Staining of white matter in human brain with Mouse anti MBP 2 mL Log in to see 6 to 8 Days
$489.50
Details
Cow Mouse Un-conjugated EIA, IHC (p), RIA   0.2 mg Log in to see 6 to 8 Days
$555.50
Details
Human Rabbit Un-conjugated EIA 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated EIA, IHC (fro), WB   0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Cow Mouse Un-conjugated EIA, IHC (fro)   2 mL Log in to see 6 to 8 Days
$456.50
Details
Cow Mouse Un-conjugated EIA, IHC (fro)   2 mL Log in to see 6 to 8 Days
$489.50
Details
Human Chicken Un-conjugated IF, WB Rat mixed neuron/glial cultures stained with Chicken anti-MBP antibody... Western blot of rat cortex homogenate showing specific immunolabeling ... 0.1 mL Log in to see 6 to 8 Days
$357.50
Details
Human Mouse Un-conjugated KAA, WB   100 μg Log in to see 3 to 4 Days
$571.07
Details
Rat Rabbit Un-conjugated ELISA, WB Western blot analysis of tissue lysates using 1 µg/mL Rabbit Anti-Myel... 40 μg Log in to see 3 to 4 Days
$147.40
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$253.00
Details

MBP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Rat (Rattus) , , , ,
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Mouse (Murine) , , , ,
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Top referenced anti-Myelin Basic Protein Antibodies

  1. Cow (Bovine) Monoclonal MBP Primary Antibody for EIA, IHC (fro) - ABIN119025 : Groome, Dawkes, Gales, Hruby, Alvord: Region-specific immunoassays for human myelin basic protein. in Journal of neuroimmunology 1986 (PubMed)
    Show all 3 references for ABIN119025

  2. Human Polyclonal MBP Primary Antibody for IF, WB - ABIN953563 : Marty, Alliot, Rutin, Fritz, Trisler, Pessac: The myelin basic protein gene is expressed in differentiated blood cell lineages and in hemopoietic progenitors. in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 3 references for ABIN953563

  3. Human Monoclonal MBP Primary Antibody for IHC (fro), IHC (p) - ABIN119023 : Groome, Dawkes, Barry, Hruby, Alvord: New monoclonal antibodies reactive with defined sequential epitopes in human myelin basic protein. in Journal of neuroimmunology 1988 (PubMed)
    Show all 3 references for ABIN119023

  4. Cow (Bovine) Monoclonal MBP Primary Antibody for EIA, IHC (fro) - ABIN119024 : Groome, Townley, Watson: Excitatory actions of FMRFamide-related peptides (FaRPs) on the neurogenic Limulus heart. in The Biological bulletin 1994 (PubMed)
    Show all 3 references for ABIN119024

  5. Human Monoclonal MBP Primary Antibody for EIA, IHC (fro) - ABIN181840 : Yon, White, Groome: Preparation of a novel monoclonal antibody specific for myelin basic protein phosphorylated on Thr98. in Journal of neuroimmunology 1995 (PubMed)
    Show all 2 references for ABIN181840

  6. Human Polyclonal MBP Primary Antibody for WB - ABIN871740 : Pribyl, Campagnoni, Kampf, Kashima, Handley, McMahon, Campagnoni: The human myelin basic protein gene is included within a 179-kilobase transcription unit: expression in the immune and central nervous systems. in Proceedings of the National Academy of Sciences of the United States of America 1993 (PubMed)
    Show all 2 references for ABIN871740

  7. Rat (Rattus) Polyclonal MBP Primary Antibody for ELISA, WB - ABIN1574105 : Kraitsy, Uecal, Grossauer, Bruckmann, Pfleger, Ropele, Fazekas, Gruenbacher, Patz, Absenger, Porubsky, Smolle-Juettner, Tezer, Molcanyi, Fasching, Schaefer: Repetitive long-term hyperbaric oxygen treatment (HBOT) administered after experimental traumatic brain injury in rats induces significant remyelination and a recovery of sensorimotor function. in PLoS ONE 2014 (PubMed)

  8. Cow (Bovine) Monoclonal MBP Primary Antibody for EIA, IHC (p) - ABIN110680 : Elfman, Kynoch, Siddle, Thompson: Rat and mouse monoclonal antibodies to human myelin basic protein. in Journal of neurochemistry 1986 (PubMed)

  9. Human Polyclonal MBP Primary Antibody for EIA - ABIN358484 : Kawamura, McLaughlin, Weissert, Forsthuber: Myelin-reactive type B T cells and T cells specific for low-affinity MHC-binding myelin peptides escape tolerance in HLA-DR transgenic mice. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)

More Antibodies against Myelin Basic Protein Interaction Partners

Human Myelin Basic Protein (MBP) interaction partners

  1. myelin basic protein has a role in activating CD4 (show CD4 Antibodies)+ and CD8 (show CD8A Antibodies)+ T lymphocytes in multiple sclerosis

  2. B cells from relapsing-remitting multiple sclerosis patients produce TNFa (show TNF Antibodies) and IL6 (show IL6 Antibodies), and present MBP85-99 peptide

  3. IL-17 (show IL17A Antibodies)- and IL-22 (show IL22 Antibodies)-secreting myelin specific CD4 (show CD4 Antibodies)(+) T cells resistant to corticoids are associated with radiological activity of multiple sclerosis in early stages of the disease, mainly among Afrodescendant patients who, normally, have worse prognosis.

  4. Studies indicate that all myelin basic protein (MBP) isoforms are intrinsically disordered proteins (IDPs) that interact via molecular recognition fragments (MoRFs), which thereby undergo local disorder-to-order transitions.

  5. Reduced myelin basic protein-induced CD4 (show CD4 Antibodies)+ T-cell autoreactivity in interferon-beta (show IFNB1 Antibodies)-treated multiple sclerosis patients may be mediated by monocyte-derived interleukin-10 (show IL10 Antibodies)

  6. Negatively charged actin and calmodulin (CaM (show CALM1 Antibodies)), as well as basic histone H1.3, inhibit MBP (show MBL2 Antibodies) hydrolysis by competing with the proteasome and MBP (show MBL2 Antibodies), respectively, for binding their counterpart.

  7. data reveal the first case of a pathophysiologically important autoantigen as a ubiquitin-independent substrate of the 26S proteasome (show Psmd4 Antibodies).

  8. Single nucleotide polymorphisms on genetic loci SOD2 (show SOD2 Antibodies), MBP (show MBL2 Antibodies) and C8orf42were not found significantly associated with advanced age-related macular degeneration in a Chinese cohort

  9. In autistic children with allergic manifestations there were increased serum levels of MBP (show MBL2 Antibodies) (and MAG (show MAG Antibodies)) compared to those without allergies.

  10. Association between MBP (show MBL2 Antibodies) 5'-side TGGA n gene polymorphism and delayed encephalopathy after acute carbon monoxide poisoning.

Pig (Porcine) Myelin Basic Protein (MBP) interaction partners

  1. Concentrations of MBP did not increase after injury in all age groups

  2. results provide a detailed picture of the MBP-CaM (show CALM Antibodies) interaction, including a 3D model of the complex between full-length proteins

  3. MBP-hydrolyzing antibodies may play an important role in multiple sclerosis pathogenesis

Cow (Bovine) Myelin Basic Protein (MBP) interaction partners

  1. Data suggest that hybrid protein composed of two different Myelin basic protein (MBP) isoforms (TandeMBP) might become a tool for in vitro assays to analyse various protein kinase (show CDK7 Antibodies) activities.

  2. trehalose completely avoid autocatalytic cleavage properties of MBP up to 4 days of incubation at 37 degrees C and pH 7.4.

  3. formation of an imine between inflammatory-derived aldehydes can lead to structural changes in MBP and a decrease in myelin stability

  4. results provide a detailed picture of the MBP-CaM (show KRIT1 Antibodies) interaction, including a 3D model of the complex between full-length proteins

  5. MBP can induce a dihydrocholesterol-dependent segregation of phases that can be further regulated by the electrolyte concentration in the subphase and the composition (type and proportion) of non-sterol lipids.

  6. Bovine MBP priming reduces expression of Foxp3 (show FOXP3 Antibodies) via nitric oxide in inducible nitric oxide synthase (show NOS2 Antibodies)-deficient mouse T cells.

  7. investigation of bovine myelin basic protein binding to triphosphoinositide

  8. There is a developmental regulation of posttranslationally modified forms of myelin basic protein into specific membrane microdomains.

  9. These results suggest that phospholipids and sulfatide and heparin may function as effective stimulators for autophosphorylation of GSK-3beta (show GSK3b Antibodies) and for the GSK-3beta (show GSK3b Antibodies)-mediated high phosphorylation of SH-binding proteins, including MBP and tau protein.

  10. Myelin basic protein (MBP), a major autoantigen in multiple sclerosis, is a potent and specific ligand for integrin alphaMbeta2 expressed mainly on phagocytic cells.

Mouse (Murine) Myelin Basic Protein (MBP) interaction partners

  1. Results show the expression of sncRNA715 in Schwann cells and its inverse correlation with Mbp mRNA in cultured cells and the sciatic nerve. Its inhibitory effect on MBP was confirmed in differentiating primary Schwann cells.

  2. Results suggest that GAL (show GAL Antibodies) is a regulator of myelination, as demonstrated by MBP synthesis, and may be one of the myelination promoters

  3. Data indicate that 18.5 kDa myelin basic protein (MBP) segment upstream of the primary SH3-ligand is involved in interaction.

  4. Data suggest that prenatal alterations in expression of various fetal brain proteins (including up-regulation of Mbp) are associated with aberrant behavioral characteristics of transgenic mice that model autism-like behavior.

  5. Data suggest that hybrid protein composed of two different Myelin basic protein (MBP) isoforms (TandeMBP) might become a tool for in vitro assays to analyse various protein kinase (show CDK7 Antibodies) activities.

  6. Data indicate a role for myelin basic protein (MBP) isoforms in protein-protein interactions during membrane and cytoskeletal extension and remodeling in oligodendrocytes (OLGs).

  7. Disappearance of 21.5 pMBP (show PGRMC2 Antibodies) corresponded to demyelination and its reappearance corresponded to prevention of demyelination.

  8. Golli-BG21 enhanced SCP1/GIP phosphatase activity, whereas PKCalpha (show PKCa Antibodies)-phosphorylated BG21 inhibited its activity, suggesting a potential role of BG21 as a molecular switch ("quick-brake mechanism") on SCP1/GIP.

  9. Myelin basic protein cleaves cell adhesion molecule (show MCAM Antibodies) L1 and promotes neuritogenesis and cell survival.

  10. MBP expression in cultured Fmr1 (show FMR1 Antibodies) KO oligodendrocytes is similar to wild type, and expression of MBP in brain homogenates of the Fmr1 (show FMR1 Antibodies) KO mouse to be similar to wild type.

Myelin Basic Protein (MBP) Antigen Profile

Protein Summary

The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.

Gene names and symbols associated with MBP

  • myelin basic protein a (mbpa) antibody
  • myelin basic protein (mbp) antibody
  • myelin basic protein (MBP) antibody
  • myelin basic protein (Mbp) antibody
  • C76307 antibody
  • cb274 antibody
  • fj33b11 antibody
  • golli-mbp antibody
  • Hmbpr antibody
  • mbp antibody
  • Mbps antibody
  • MGC115135 antibody
  • mld antibody
  • R75289 antibody
  • shi antibody
  • wu:fj33b11 antibody
  • wu:fq15b02 antibody
  • zgc:136630 antibody

Protein level used designations for MBP

myelin basic protein , myelin A1 protein , myelin membrane encephalitogenic protein , 20 kDa microtubule-stabilizing protein , microtubule-stabilizing protein , Golli-Mbp; myelin basic protein , Golli-Mbp; myelin basic protein; myelin basic protein S , MBP S , myelin basic protein Golli-mbp , myelin basic protein S , myelin deficient , shiverer , Golli-mbp

GENE ID SPECIES
326281 Danio rerio
549346 Xenopus (Silurana) tropicalis
734401 Xenopus laevis
4155 Homo sapiens
414286 Sus scrofa
618684 Bos taurus
101109407 Ovis aries
100731253 Cavia porcellus
396217 Gallus gallus
24547 Rattus norvegicus
17196 Mus musculus
476160 Canis lupus familiaris
399102 Xenopus laevis
455522 Pan troglodytes
100174122 Pongo abelii
Selected quality suppliers for anti-Myelin Basic Protein (MBP) Antibodies
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