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Myelin Basic Protein Proteins (MBP)

The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. Additionally we are shipping Myelin Basic Protein Antibodies (197) and Myelin Basic Protein Kits (48) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MBP 4155 P02686
MBP 24547 P02688
MBP 17196 P04370
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Top Myelin Basic Protein Proteins at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human GST tag Myelin Basic Protein (MBP) (AA 134-304), (partial) protein (GST tag) 50 μg Log in to see 9 to 11 Days
$242.00
Details
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 11 to 13 Days
$492.80
Details
Yeast Carcharhinus obscurus His tag   1 mg Log in to see 56 to 66 Days
$2,262.33
Details
Yeast Heterodontus francisci His tag   1 mg Log in to see 56 to 66 Days
$2,343.00
Details
Yeast REACT_Little Skate His tag   1 mg Log in to see 56 to 66 Days
$2,343.00
Details
Yeast REACT_Dogfish His tag   1 mg Log in to see 56 to 66 Days
$2,343.00
Details
Yeast Guinea Pig His tag   1 mg Log in to see 56 to 66 Days
$2,383.33
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,387.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,388.83
Details
Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days
$2,396.17
Details

MBP Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus)

Mouse (Murine)

More Proteins for Myelin Basic Protein (MBP) Interaction Partners

Human Myelin Basic Protein (MBP) interaction partners

  1. This study observed a significantly increased myelin basic protein (MBP) and nuclear distribution protein nudE-like 1 (NDEL1 (show NDEL1 Proteins)) mRNA levels in FEP patients compared with controls.

  2. myelin basic protein has a role in activating CD4 (show CD4 Proteins)+ and CD8 (show CD8A Proteins)+ T lymphocytes in multiple sclerosis

  3. B cells from relapsing-remitting multiple sclerosis patients produce TNFa (show TNF Proteins) and IL6 (show IL6 Proteins), and present MBP85-99 peptide

  4. IL-17 (show IL17A Proteins)- and IL-22 (show IL22 Proteins)-secreting myelin specific CD4 (show CD4 Proteins)(+) T cells resistant to corticoids are associated with radiological activity of multiple sclerosis in early stages of the disease, mainly among Afrodescendant patients who, normally, have worse prognosis.

  5. Studies indicate that all myelin basic protein (MBP) isoforms are intrinsically disordered proteins (IDPs) that interact via molecular recognition fragments (MoRFs), which thereby undergo local disorder-to-order transitions.

  6. Reduced myelin basic protein-induced CD4 (show CD4 Proteins)+ T-cell autoreactivity in interferon-beta (show IFNB1 Proteins)-treated multiple sclerosis patients may be mediated by monocyte-derived interleukin-10 (show IL10 Proteins)

  7. Negatively charged actin and calmodulin (CaM (show CALM1 Proteins)), as well as basic histone H1.3, inhibit MBP (show MBL2 Proteins) hydrolysis by competing with the proteasome and MBP (show MBL2 Proteins), respectively, for binding their counterpart.

  8. data reveal the first case of a pathophysiologically important autoantigen as a ubiquitin-independent substrate of the 26S proteasome (show Psmd4 Proteins).

  9. Single nucleotide polymorphisms on genetic loci SOD2 (show SOD2 Proteins), MBP (show MBL2 Proteins) and C8orf42were not found significantly associated with advanced age-related macular degeneration in a Chinese cohort

  10. In autistic children with allergic manifestations there were increased serum levels of MBP (show MBL2 Proteins) (and MAG (show MAG Proteins)) compared to those without allergies.

Pig (Porcine) Myelin Basic Protein (MBP) interaction partners

  1. Concentrations of MBP did not increase after injury in all age groups

  2. results provide a detailed picture of the MBP-CaM (show CALM Proteins) interaction, including a 3D model of the complex between full-length proteins

  3. MBP-hydrolyzing antibodies may play an important role in multiple sclerosis pathogenesis

Cow (Bovine) Myelin Basic Protein (MBP) interaction partners

  1. Data suggest that hybrid protein composed of two different Myelin basic protein (MBP) isoforms (TandeMBP) might become a tool for in vitro assays to analyse various protein kinase (show CDK7 Proteins) activities.

  2. trehalose completely avoid autocatalytic cleavage properties of MBP up to 4 days of incubation at 37 degrees C and pH 7.4.

  3. formation of an imine between inflammatory-derived aldehydes can lead to structural changes in MBP and a decrease in myelin stability

  4. results provide a detailed picture of the MBP-CaM (show KRIT1 Proteins) interaction, including a 3D model of the complex between full-length proteins

  5. MBP can induce a dihydrocholesterol-dependent segregation of phases that can be further regulated by the electrolyte concentration in the subphase and the composition (type and proportion) of non-sterol lipids.

  6. Bovine MBP priming reduces expression of Foxp3 (show FOXP3 Proteins) via nitric oxide in inducible nitric oxide synthase (show NOS2 Proteins)-deficient mouse T cells.

  7. investigation of bovine myelin basic protein binding to triphosphoinositide

  8. There is a developmental regulation of posttranslationally modified forms of myelin basic protein into specific membrane microdomains.

  9. These results suggest that phospholipids and sulfatide and heparin may function as effective stimulators for autophosphorylation of GSK-3beta and for the GSK-3beta-mediated high phosphorylation of SH-binding proteins, including MBP and tau protein.

  10. Myelin basic protein (MBP), a major autoantigen in multiple sclerosis, is a potent and specific ligand for integrin alphaMbeta2 expressed mainly on phagocytic cells.

Mouse (Murine) Myelin Basic Protein (MBP) interaction partners

  1. to further characterize the mechanism regulating mbp transcription, study defined M3 structure/function relationships; multiple M3 regulatory element combinations were found to drive expression in oligodendrocytes and Schwann cells with a minimal 129 bp sequence conferring expression in oligodendrocytes throughout myelin elaboration, maintenance and repair

  2. Results show the expression of sncRNA715 in Schwann cells and its inverse correlation with Mbp mRNA in cultured cells and the sciatic nerve. Its inhibitory effect on MBP was confirmed in differentiating primary Schwann cells.

  3. Results suggest that GAL (show GAL Proteins) is a regulator of myelination, as demonstrated by MBP synthesis, and may be one of the myelination promoters

  4. Data indicate that 18.5 kDa myelin basic protein (MBP) segment upstream of the primary SH3-ligand is involved in interaction.

  5. Data suggest that prenatal alterations in expression of various fetal brain proteins (including up-regulation of Mbp) are associated with aberrant behavioral characteristics of transgenic mice that model autism-like behavior.

  6. Data suggest that hybrid protein composed of two different Myelin basic protein (MBP) isoforms (TandeMBP) might become a tool for in vitro assays to analyse various protein kinase (show CDK7 Proteins) activities.

  7. Data indicate a role for myelin basic protein (MBP) isoforms in protein-protein interactions during membrane and cytoskeletal extension and remodeling in oligodendrocytes (OLGs).

  8. Disappearance of 21.5 pMBP (show PGRMC2 Proteins) corresponded to demyelination and its reappearance corresponded to prevention of demyelination.

  9. Golli-BG21 enhanced SCP1/GIP phosphatase activity, whereas PKCalpha (show PKCa Proteins)-phosphorylated BG21 inhibited its activity, suggesting a potential role of BG21 as a molecular switch ("quick-brake mechanism") on SCP1/GIP.

  10. Myelin basic protein cleaves cell adhesion molecule (show MCAM Proteins) L1 and promotes neuritogenesis and cell survival.

Myelin Basic Protein (MBP) Protein Profile

Protein Summary

The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.

Gene names and symbols associated with Myelin Basic Protein Proteins (MBP)

  • myelin basic protein a (mbpa)
  • myelin basic protein (mbp)
  • myelin basic protein (MBP)
  • myelin basic protein (Mbp)
  • C76307 protein
  • cb274 protein
  • fj33b11 protein
  • golli-mbp protein
  • Hmbpr protein
  • mbp protein
  • Mbps protein
  • MGC115135 protein
  • mld protein
  • R75289 protein
  • shi protein
  • wu:fj33b11 protein
  • wu:fq15b02 protein
  • zgc:136630 protein

Protein level used designations for Myelin Basic Protein Proteins (MBP)

myelin basic protein , myelin A1 protein , myelin membrane encephalitogenic protein , 20 kDa microtubule-stabilizing protein , microtubule-stabilizing protein , Golli-Mbp; myelin basic protein , Golli-Mbp; myelin basic protein; myelin basic protein S , MBP S , myelin basic protein Golli-mbp , myelin basic protein S , myelin deficient , shiverer , Golli-mbp

GENE ID SPECIES
326281 Danio rerio
549346 Xenopus (Silurana) tropicalis
734401 Xenopus laevis
4155 Homo sapiens
414286 Sus scrofa
618684 Bos taurus
101109407 Ovis aries
100731253 Cavia porcellus
396217 Gallus gallus
24547 Rattus norvegicus
17196 Mus musculus
476160 Canis lupus familiaris
399102 Xenopus laevis
455522 Pan troglodytes
100174122 Pongo abelii
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