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Myeloid Leukemia Factor 1 Proteins (MLF1)

MLF1 encodes an oncoprotein which is thought to play a role in the phenotypic determination of hemopoetic cells. Additionally we are shipping MLF1 Antibodies (111) and MLF1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MLF1 4291 P58340
MLF1 17349 Q9QWV4
Rat MLF1 MLF1 310483  
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Top MLF1 Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,696.83
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,704.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$364.64
Details
HOST_Escherichia coli (E. coli) Human His tag   5 μg Log in to see 6 to 11 Days
$142.86
Details
Human Un-conjugated   5 μg Log in to see 6 Days
$168.54
Details

MLF1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Top referenced MLF1 Proteins

  1. Human MLF1 Protein expressed in Escherichia coli (E. coli) - ABIN667346 : Winteringham, Kobelke, Williams, Ingley, Klinken: Myeloid Leukemia Factor 1 inhibits erythropoietin-induced differentiation, cell cycle exit and p27Kip1 accumulation. in Oncogene 2004 (PubMed)
    Show all 2 references for ABIN667346

More Proteins for Myeloid Leukemia Factor 1 (MLF1) Interaction Partners

Human Myeloid Leukemia Factor 1 (MLF1) interaction partners

  1. Data indicte that acute myeloid leukemia (show BCL11A Proteins) (AML (show RUNX1 Proteins)) with NPM1 (show NPM1 Proteins)-MLF1 and AML (show RUNX1 Proteins) with NPM1 (show NPM1 Proteins) mutations showed similar immunophenotypical and molecular features, including gene mutation patterns and gene expression profiling (GEP).

  2. The subcellular localization of full-length human MLF1 is 14-3-3epsilon-independent.

  3. changes in the subcellular localization of NPM (show NPM1 Proteins), due to alterations in the relative abundance of NPM (show NPM1 Proteins) and NPM (show NPM1 Proteins)-MLF1 proteins, may contribute to the enhanced myeloid progenitor activity of Npm (show NPM1 Proteins) +/- cells

  4. Data present the high-resolution crystal structure of this binding motif [MLF1(29-42)pSer34] in complex with 14-3-3epsilon and analyse the interaction with isothermal titration calorimetry.

  5. MLF1 gene rearrangement is associated with acute myeloid leukemia (show BCL11A Proteins).

  6. phosphorylation of 14-3-3 (show YWHAQ Proteins) binding site by MADM (show ADAM10 Proteins)

  7. These findings suggest that an NPM (show NPM1 Proteins)/MLF1 fusion is the primary molecular abnormality in t(3;5) MDS (show PAFAH1B1 Proteins) and AML (show RUNX1 Proteins) with multilineage dysplasia, and that cases with NPM (show NPM1 Proteins)/MLF1 may be clinically distinct from other MDS (show PAFAH1B1 Proteins)-associated disease

  8. Over-expression of MLF1 has little impact on skeletal muscle function in mice; progressive formation of protein aggregates in muscle are not necessarily pathogenic; MLF1 and MRJ (show DNAJB6 Proteins) may function together to ameliorate the toxic effects of mutant proteins.

  9. shuttling of MLF1 is critical for the regulation of cell proliferation and a disturbance in the shuttling balance increases the cell's susceptibility to oncogenic transformation

Mouse (Murine) Myeloid Leukemia Factor 1 (MLF1) interaction partners

  1. Ectopically expressed MLF1 could be responsible for the pathological apoptosis in early myelodysplastic syndrome (MDS (show MECOM Proteins)) patients.

  2. Mlf1 translocates between nucleus and cytoplasm, associates with a novel hnRNP (show HNRNPH2 Proteins), and influences gene expression

  3. shuttling of MLF1 is critical for the regulation of cell proliferation and a disturbance in the shuttling balance increases the cell's susceptibility to oncogenic transformation

MLF1 Protein Profile

Protein Summary

This gene encodes an oncoprotein which is thought to play a role in the phenotypic determination of hemopoetic cells. Translocations between this gene and nucleophosmin have been associated with myelodysplastic syndrome and acute myeloid leukemia. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MLF1

  • myeloid leukemia factor 1 (MLF1)
  • myeloid leukemia factor 1 (mlf1)
  • myeloid leukemia factor 1 (Mlf1)
  • HLS7 protein
  • MLF1 protein

Protein level used designations for MLF1

myeloid leukemia factor 1 , myelodysplasia-myeloid leukemia factor 1 , hematopoietic lineage switch 7

GENE ID SPECIES
425019 Gallus gallus
460811 Pan troglodytes
477127 Canis lupus familiaris
496153 Xenopus laevis
100135130 Xenopus (Silurana) tropicalis
4291 Homo sapiens
17349 Mus musculus
310483 Rattus norvegicus
533379 Bos taurus
100174592 Pongo abelii
Selected quality suppliers for MLF1 Proteins (MLF1)
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