Myeloid Leukemia Factor 1 (MLF1) ELISA Kits

MLF1 encodes an oncoprotein which is thought to play a role in the phenotypic determination of hemopoetic cells. Additionally we are shipping MLF1 Antibodies (120) and MLF1 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MLF1 4291 P58340
MLF1 17349 Q9QWV4
Anti-Rat MLF1 MLF1 310483  
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Top MLF1 ELISA Kits at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse
  96 Tests Log in to see 15 to 18 Days
$875.60
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Human
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$875.60
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Cow
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$1,029.60
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More ELISA Kits for MLF1 Interaction Partners

Human Myeloid Leukemia Factor 1 (MLF1) interaction partners

  1. Mutation in HTT (show HTT ELISA Kits) causes Huntington's disease (HD); aggregates of mutated HTT (show HTT ELISA Kits) cause apoptosis in neurons of HD patients. Data suggest that both MLF1 and MLF2 preferentially interact with mutated N-terminal HTT (show HTT ELISA Kits); MLF1/MLF2 reduce number of neurons (Neuro2A cell line) containing mutant HTT (show HTT ELISA Kits) aggregates and subsequent apoptosis. (HTT (show HTT ELISA Kits) = Huntingtin (show HTT ELISA Kits) protein; MLF = myeloid leukemia (show BCL11A ELISA Kits) factor)

  2. The data indicate that MLF1 serves as a proapoptotic antagonist that interacts with the HAX1 (show HAX1 ELISA Kits)/HtrA2-OMI (show HTRA2 ELISA Kits)/PARL (show PARL ELISA Kits) (HOP (show STIP1 ELISA Kits)) mitochondrial complex to modulate cell survival.

  3. SNP associated with neuroblastoma (show ARHGEF16 ELISA Kits) resides upstream of the MLF1. Gene silencing of MLF1 in neuroblastoma (show ARHGEF16 ELISA Kits) cells results in significant growth inhibition.

  4. Data indicte that acute myeloid leukemia (show BCL11A ELISA Kits) (AML (show RUNX1 ELISA Kits)) with NPM1 (show NPM1 ELISA Kits)-MLF1 and AML (show RUNX1 ELISA Kits) with NPM1 (show NPM1 ELISA Kits) mutations showed similar immunophenotypical and molecular features, including gene mutation patterns and gene expression profiling (GEP (show GNA12 ELISA Kits)).

  5. The subcellular localization of full-length human MLF1 is 14-3-3epsilon-independent.

  6. changes in the subcellular localization of NPM (show NPM1 ELISA Kits), due to alterations in the relative abundance of NPM (show NPM1 ELISA Kits) and NPM (show NPM1 ELISA Kits)-MLF1 proteins, may contribute to the enhanced myeloid progenitor activity of Npm (show NPM1 ELISA Kits) +/- cells

  7. Data present the high-resolution crystal structure of this binding motif [MLF1(29-42)pSer34] in complex with 14-3-3epsilon and analyse the interaction with isothermal titration calorimetry.

  8. MLF1 gene rearrangement is associated with acute myeloid leukemia (show BCL11A ELISA Kits).

  9. phosphorylation of 14-3-3 (show YWHAQ ELISA Kits) binding site by MADM (show ADAM10 ELISA Kits)

  10. These findings suggest that an NPM (show NPM1 ELISA Kits)/MLF1 fusion is the primary molecular abnormality in t(3;5) MDS (show PAFAH1B1 ELISA Kits) and AML (show RUNX1 ELISA Kits) with multilineage dysplasia, and that cases with NPM (show NPM1 ELISA Kits)/MLF1 may be clinically distinct from other MDS (show PAFAH1B1 ELISA Kits)-associated disease

Mouse (Murine) Myeloid Leukemia Factor 1 (MLF1) interaction partners

  1. The data indicate that MLF1 serves as a proapoptotic antagonist that interacts with the HAX1 (show HAX1 ELISA Kits)/HtrA2-OMI (show HTRA2 ELISA Kits)/PARL (show PARL ELISA Kits) (HOP (show STIP1 ELISA Kits)) mitochondrial complex to modulate cell survival.

  2. Ectopically expressed MLF1 could be responsible for the pathological apoptosis in early myelodysplastic syndrome (MDS (show MECOM ELISA Kits)) patients.

  3. Mlf1 translocates between nucleus and cytoplasm, associates with a novel hnRNP, and influences gene expression

  4. shuttling of MLF1 is critical for the regulation of cell proliferation and a disturbance in the shuttling balance increases the cell's susceptibility to oncogenic transformation

MLF1 Antigen Profile

Antigen Summary

This gene encodes an oncoprotein which is thought to play a role in the phenotypic determination of hemopoetic cells. Translocations between this gene and nucleophosmin have been associated with myelodysplastic syndrome and acute myeloid leukemia. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MLF1

  • myeloid leukemia factor 1 (MLF1) antibody
  • myeloid leukemia factor 1 (mlf1) antibody
  • myeloid leukemia factor 1 (Mlf1) antibody
  • HLS7 antibody
  • MLF1 antibody

Protein level used designations for MLF1

myeloid leukemia factor 1 , myelodysplasia-myeloid leukemia factor 1 , hematopoietic lineage switch 7

GENE ID SPECIES
425019 Gallus gallus
460811 Pan troglodytes
477127 Canis lupus familiaris
496153 Xenopus laevis
100135130 Xenopus (Silurana) tropicalis
4291 Homo sapiens
17349 Mus musculus
310483 Rattus norvegicus
533379 Bos taurus
100174592 Pongo abelii
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