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anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1) Antibodies

Histone methyltransferase that plays an essential role in early development and hematopoiesis. Additionally we are shipping Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 Kits (20) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Rat MLL1 MLL1 315606  
MLL1 214162 P55200
MLL1    
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Top anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 Antibodies at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated DB Dot blot analysis of Phospho-TJP2-S978 Antibody Phospho-specific Pab  on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$304.50
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 11 to 16 Days
$531.14
Details
Human Rabbit APC ELISA   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit FITC ELISA   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit HRP ELISA   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit PE ELISA   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit Biotin ELISA   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit Un-conjugated   400 μL Log in to see 6 Days
$200.00
Details

MLL1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human , ,


, , , , ,

More Antibodies against Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 Interaction Partners

Mouse (Murine) Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1) interaction partners

  1. Data suggest that RAS-homolog enriched in brain protein (Rheb1) promotes MLL-AF9 fusion protein initiated acute myeloid leukemia (AML) progression through target of rapamycin complex 1 (mTORC1) signaling pathway.

  2. HoxBlinc RNA Recruits Set1 (show SETD1A Antibodies)/MLL (show MLL Antibodies) Complexes to Activate Hox (show MSH2 Antibodies) Gene Expression Patterns and Mesoderm Lineage Development.

  3. MLL1 and DOT1L (show DOT1L Antibodies) cooperate with meningioma-1 to induce acute myeloid leukemia (show BCL11A Antibodies).

  4. Set1 (show SETD1A Antibodies) role in cellular reprogramming and its interactions with Dpy30 (show DPY30 Antibodies),Myc (show MYC Antibodies),Sox2 (show SOX2 Antibodies) and Ash2l (show ASH2L Antibodies) reprogramming factors

  5. The present study examined the mechanism underlying the development of KMT2A (MLL (show MLL Antibodies))-rearranged infant leukemia in response to in utero exposure to etoposide in a mouse model.

  6. We have demonstrated that the Mll1 gene is critical to Th1 (show HAND1 Antibodies) differentiation in humans and mice

  7. MLL is the key Taspase1 substrate whose cleavage is required for MMTV-neuinduced tumor formation.

  8. Data indicate that Meis homeobox 1 (MEIS1 (show MEIS1 Antibodies)) is required for the maintenance of myeloid-lymphoid leukemia protein MLL (show MLL Antibodies)-fusion gene leukemia, and hepatic leukemia factor (HLF (show HLF Antibodies))is a key downstream mediator of Meis1 (show MEIS1 Antibodies).

  9. Using a PDK1 (show PDPK1 Antibodies) conditional deletion MLL (show MLL Antibodies)-AF9 (show MLLT3 Antibodies) murine AML (show RUNX1 Antibodies) model, we revealed that the deletion of PDK1 (show PDPK1 Antibodies) prolonged the survival of AML (show RUNX1 Antibodies) mice by inducing LSC (show ARHGEF1 Antibodies) apoptosis

  10. Recruited MOF (show KAT8 Antibodies) activity, and not the intrinsic HMT (show HNMT Antibodies) activity of MLL1, is central for the maintenance of HSC (show FUT1 Antibodies) target genes. In addition, this work reveals a role for SIRT1 (show SIRT1 Antibodies) in opposing MLL1 function.

Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1) Antigen Profile

Protein Summary

Histone methyltransferase that plays an essential role in early development and hematopoiesis. Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the MLL1/MLL complex, it specifically mediates H3K4me, a specific tag for epigenetic transcriptional activation. Has weak methyltransferase activity by itself, and requires other component of the MLL1/MLL complex to obtain full methyltransferase activity. Has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', while it has higher activity toward H3 acetylated on 'Lys-9'. Required for transcriptional activation of HOXA9. Promotes PPP1R15A-induced apoptosis (By similarity).

Gene names and symbols associated with MLL1

  • lysine (K)-specific methyltransferase 2A (Kmt2a) antibody
  • 6430520K01 antibody
  • ALL-1 antibody
  • All1 antibody
  • Cxxc7 antibody
  • HRX antibody
  • HTRX1 antibody
  • mKIAA4050 antibody
  • Mll antibody
  • Mll1 antibody

Protein level used designations for MLL1

Mixed-lineage leukemia (also acute lymphocytic leukemia 1 or tritorax Drosophila gene) , histone-lysine N-methyltransferase MLL , myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) , myeloid/lymphoid or mixed-lineage leukemia 1 , histone-lysine N-methyltransferase 2A , lysine N-methyltransferase 2A , myeloid/lymphoid or mixed-lineage leukemia protein 1 , trithorax Drosophila , zinc finger protein HRX

GENE ID SPECIES
315606 Rattus norvegicus
214162 Mus musculus
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