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Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1) ELISA Kits

Histone methyltransferase that plays an essential role in early development and hematopoiesis. Additionally we are shipping Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 Antibodies (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MLL1 315606  
MLL1 214162 P55200
MLL1    
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Top Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 ELISA Kits at antibodies-online.com

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Rat
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$785.71
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Mouse
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Rabbit
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Human
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Guinea Pig
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$801.43
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Pig
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Dog
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Goat
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Monkey
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$817.14
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Chicken
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$864.29
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More ELISA Kits for Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 Interaction Partners

Mouse (Murine) Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1) interaction partners

  1. Data suggest that RAS-homolog enriched in brain protein (Rheb1) promotes MLL-AF9 fusion protein initiated acute myeloid leukemia (AML) progression through target of rapamycin complex 1 (mTORC1) signaling pathway.

  2. HoxBlinc RNA Recruits Set1 (show SETD1A ELISA Kits)/MLL (show MLL ELISA Kits) Complexes to Activate Hox (show MSH2 ELISA Kits) Gene Expression Patterns and Mesoderm Lineage Development.

  3. MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia (show BCL11A ELISA Kits).

  4. Set1 role in cellular reprogramming and its interactions with Dpy30,Myc,Sox2 and Ash2l reprogramming factors

  5. The present study examined the mechanism underlying the development of KMT2A (MLL (show MLL ELISA Kits))-rearranged infant leukemia in response to in utero exposure to etoposide in a mouse model.

  6. We have demonstrated that the Mll1 gene is critical to Th1 (show HAND1 ELISA Kits) differentiation in humans and mice

  7. MLL is the key Taspase1 substrate whose cleavage is required for MMTV-neuinduced tumor formation.

  8. Data indicate that Meis homeobox 1 (MEIS1 (show MEIS1 ELISA Kits)) is required for the maintenance of myeloid-lymphoid leukemia protein MLL (show MLL ELISA Kits)-fusion gene leukemia, and hepatic leukemia factor (HLF (show HLF ELISA Kits))is a key downstream mediator of Meis1 (show MEIS1 ELISA Kits).

  9. Using a PDK1 (show PDPK1 ELISA Kits) conditional deletion MLL (show MLL ELISA Kits)-AF9 (show MLLT3 ELISA Kits) murine AML (show RUNX1 ELISA Kits) model, we revealed that the deletion of PDK1 (show PDPK1 ELISA Kits) prolonged the survival of AML (show RUNX1 ELISA Kits) mice by inducing LSC (show ARHGEF1 ELISA Kits) apoptosis

  10. Recruited MOF (show KAT8 ELISA Kits) activity, and not the intrinsic HMT (show HNMT ELISA Kits) activity of MLL1, is central for the maintenance of HSC (show FUT1 ELISA Kits) target genes. In addition, this work reveals a role for SIRT1 (show SIRT1 ELISA Kits) in opposing MLL1 function.

Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1) Antigen Profile

Antigen Summary

Histone methyltransferase that plays an essential role in early development and hematopoiesis. Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the MLL1/MLL complex, it specifically mediates H3K4me, a specific tag for epigenetic transcriptional activation. Has weak methyltransferase activity by itself, and requires other component of the MLL1/MLL complex to obtain full methyltransferase activity. Has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', while it has higher activity toward H3 acetylated on 'Lys-9'. Required for transcriptional activation of HOXA9. Promotes PPP1R15A-induced apoptosis (By similarity).

Gene names and symbols associated with MLL1

  • lysine (K)-specific methyltransferase 2A (Kmt2a) antibody
  • 6430520K01 antibody
  • ALL-1 antibody
  • All1 antibody
  • Cxxc7 antibody
  • HRX antibody
  • HTRX1 antibody
  • mKIAA4050 antibody
  • Mll antibody
  • Mll1 antibody

Protein level used designations for MLL1

Mixed-lineage leukemia (also acute lymphocytic leukemia 1 or tritorax Drosophila gene) , histone-lysine N-methyltransferase MLL , myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) , myeloid/lymphoid or mixed-lineage leukemia 1 , histone-lysine N-methyltransferase 2A , lysine N-methyltransferase 2A , myeloid/lymphoid or mixed-lineage leukemia protein 1 , trithorax Drosophila , zinc finger protein HRX

GENE ID SPECIES
315606 Rattus norvegicus
214162 Mus musculus
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