anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 1 (MLLT1) Antibodies

Capable of activating transcription from synthetic reporter genes in both lymphoid and myeloid cells.. Additionally we are shipping MLLT1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MLLT1 301119  
MLLT1 4298 Q03111
MLLT1 64144  
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Top anti-MLLT1 Antibodies at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-MLLT1 Antibody Titration: 1.4ug/mlPositive Control: Raji cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-MLLT1 Pab (ABIN390126) in A257 cell line lysate (35 µg/lane). MLLT1(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: MLLT1 Antibody [NBP1-84840] - Staining of human hippocampus shows strong cytoplasmic and nucleolar positivity in neuronal cells. Immunocytochemistry/Immunofluorescence: MLLT1 Antibody [NBP1-84840] Staining of human cell line U-251MG shows positivity in nucleoli & nucleus but not nucleoli. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated IHC (p), ELISA Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with MLLT1 antibody ABIN214673 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated IP 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: MLLT1 Antibody [NBP1-26653] - Section of human testicular seminoma. 0.1 mL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated IHC, ELISA 0.05 mg Log in to see 2 to 3 Days
$515.63
Details

MLLT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Human , , ,
,
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, , , , ,
Mouse (Murine)


Top referenced anti-MLLT1 Antibodies

  1. Cow (Bovine) Polyclonal MLLT1 Primary Antibody for WB - ABIN2777536 : Nie, Pang, Inoue, Knox: Transcriptional regulation of cyclooxygenase 2 by bradykinin and interleukin-1beta in human airway smooth muscle cells: involvement of different promoter elements, transcription factors, and histone h4 acetylation. in Molecular and cellular biology 2003 (PubMed)
    Show all 2 references for 2777536

  2. Human Polyclonal MLLT1 Primary Antibody for WB - ABIN390126 : Bitoun, Oliver, Davies: The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling. in Human molecular genetics 2007 (PubMed)

  3. Human Polyclonal MLLT1 Primary Antibody for ICC, IF - ABIN4334892 : Perlman, Gadd, Arold, Radhakrishnan, Gerhard, Jennings, Huff, Guidry Auvil, Davidsen, Dome, Meerzaman, Hsu, Nguyen, Anderson, Ma, Mungall, Moore, Marra, Mullighan, Ma, Wheeler, Hampton et al.: MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours. ... in Nature communications 2015 (PubMed)

More Antibodies against MLLT1 Interaction Partners

Human Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 1 (MLLT1) interaction partners

  1. data identify ENL as a histone acetylation reader that regulates oncogenic transcriptional programs in acute myeloid leukaemia, and suggest that displacement of ENL from chromatin may be a promising epigenetic therapy, alone or in combination with BET inhibitors, for aggressive leukaemia

  2. MLL (show MLL Antibodies)-ENL dysregulated the proliferative and repopulating capacity of hematopoietic stem cells.

  3. Recurrent mutations within Wilms tumours involve the highly conserved YEATS domain of MLLT1.

  4. Novel splice isoform of Mllt1 is documented and confirmed that both Mllt1 mRNA isoforms are translated. The data support that MLLT1 protein isoforms display distinct stage-specific expression during spermiogenesis and adult tissues.

  5. Data suggest that AT mutated protein ATM (show ATM Antibodies)-dependent phosphorylation of ENL (MLLT1) protein functions as switch from elongation to Polycomb (show CBX2 Antibodies)-mediated repression to preserve genome integrity.

  6. AF9 and its homolog ENL directly interact with AF4.

  7. MLL (show MLL Antibodies)-ENL Interaction with CBX8 (show CBX8 Antibodies) Is Required for Efficient Transformation.

  8. Data from a follow-up study in Rome suggest a particularly favorable prognosis for patients with acute lymphoblastic leukemia expressing the MLL (show MLL Antibodies)/ENL fusion gene.

  9. Three-way translocation involving MLL (show MLL Antibodies), MLLT1, and a novel third partner, NRXN1 (show NRXN1 Antibodies), in a patient with acute lymphoblastic leukemia and t(2;19;11) (p12 (show POLE4 Antibodies);p13.3;q23).

  10. ENL chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner.

Mouse (Murine) Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 1 (MLLT1) interaction partners

  1. data identify ENL as a histone acetylation reader that regulates oncogenic transcriptional programs in acute myeloid leukaemia, and suggest that displacement of ENL from chromatin may be a promising epigenetic therapy, alone or in combination with BET inhibitors, for aggressive leukaemia

  2. define a specific pairing of two amino acids that creates a salt bridge between MLLT1/3 and AFF proteins that is critically important for MLL (show MLL Antibodies)-mediated transformation of HPCs

  3. demonstrate BAM11 transcriptional co-activation activity and its functional interaction with Btk (show BTK Antibodies)

  4. An intimate association between MLL (show MLL Antibodies) and RNA pol II (show POLR2F Antibodies) occurs at MLL (show MLL Antibodies) target genes in vivo that is required for normal initiation and/or transcriptional elongation.

  5. Overlapping expression of Af9 (show MLLT3 Antibodies) with Af4/Aff1 and Fmr2/Aff2 (show AFF2 Antibodies), two genes that are also related to neurodevelopmental diseases, as well as with the highly homologous Enl.

  6. Even genetically complex leukemias can be reversed on inactivation of the initiating MLL (show MLL Antibodies) fusion.

MLLT1 Antigen Profile

Protein Summary

Capable of activating transcription from synthetic reporter genes in both lymphoid and myeloid cells.

Gene names and symbols associated with MLLT1

  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 (Mllt1) antibody
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 (MLLT1) antibody
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 1 (mllt1) antibody
  • AA407901 antibody
  • BAM11 antibody
  • ENL antibody
  • LTG19 antibody
  • MGC84026 antibody
  • MLLT1 antibody
  • YEATS1 antibody

Protein level used designations for MLLT1

myeloid/lymphoid or mixed lineage leukemia translocation to 1 homolog , myeloid/lymphoid or mixed lineage-leukemia translocation to 1 homolog , protein ENL , myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 , myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 1 , ENL/MLL fusion , MLLT1/MLL fusion , YEATS domain-containing protein 1 , leukemia-associated protein MLLT1 , myeloid/lymphoid or mixed lineage-leukemia translocation to 4 homolog , trithorax

GENE ID SPECIES
301119 Rattus norvegicus
420089 Gallus gallus
447347 Xenopus laevis
485023 Canis lupus familiaris
504458 Bos taurus
702105 Macaca mulatta
740990 Pan troglodytes
100019539 Monodelphis domestica
100065400 Equus caballus
100158574 Xenopus (Silurana) tropicalis
4298 Homo sapiens
64144 Mus musculus
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