Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 3 (MLLT3) ELISA Kits

mouse homolog regulates pattern formation during embryogenesis [RGD, Feb 2006].. Additionally we are shipping Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 3 Antibodies (84) and Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 3 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human MLLT3 MLLT3 4300 P42568
Anti-Mouse MLLT3 MLLT3 70122 A2AM29
Anti-Rat MLLT3 MLLT3 114510  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

More ELISA Kits for Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 3 Interaction Partners

Human Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 3 (MLLT3) interaction partners

  1. MLL (show MLL ELISA Kits)-AF9 fusion is associated with acute myeloid leukemia (show BCL11A ELISA Kits).

  2. Structural insights into H3 histone (show HIST1H3B ELISA Kits) crotonyl-lysine recognition by the AF9 YEATS domain have been presented.

  3. A luciferase reporter gene assay revealed that hsp70 promoter activation is enhanced by the transcriptional co-activator AF9 and splicing mediator SNRPE, but suppressed by the coiled-coil domain-containing protein CCDC127.

  4. YEATS domain of AF9 directly links histone crotonylation to active transcription.

  5. Results show that human MLL (show MLL ELISA Kits)-AF9 expression in mouse long-term hematopoietic stem cells causes invasive, chemoresistant acute myeloid leukemia (show BCL11A ELISA Kits) that expresses genes related to epithelial-mesenchymal transition.

  6. Results show that MLL (show MLL ELISA Kits)-AF9 reduces Id2 and increases E2-2 (show TCF4 ELISA Kits) expression to drive and sustain leukemia stem cell potential in MLL (show MLL ELISA Kits)-rearranged acute myeloid leukemia (show BCL11A ELISA Kits) (AML (show RUNX1 ELISA Kits)). Low expression of Id2 or of an Id2 gene signature is associated with poor prognosis in not only MLL (show MLL ELISA Kits)-rearranged but also t(8;21) AML (show RUNX1 ELISA Kits) patients.

  7. Exploring the mechanism how AF9 recognizes and binds H3K9ac by molecular dynamics simulations and free energy calculations.

  8. Studies identified the evolutionarily conserved Af9 YEATS domain as a novel acetyllysine-binding module and established a direct link between histone acetylation and DOT1L (show DOT1L ELISA Kits)-mediated H3K79 methylation in transcription control.

  9. AF9 and its homolog ENL directly interact with AF4.

  10. Abrogation of Rac1 signaling causes DNA double-strand breaks in acute monocytic leukemia (show KAT6B ELISA Kits) cells harbouring the MLL (show MLL ELISA Kits)-AF9 oncogene (show RAB1A ELISA Kits).

Mouse (Murine) Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 3 (MLLT3) interaction partners

  1. YEATS domain of AF9 directly links histone crotonylation to active transcription.

  2. Data suggest that RAS-homolog enriched in brain protein (Rheb1) promotes MLL-AF9 fusion protein initiated acute myeloid leukemia (AML) progression through target of rapamycin complex 1 (mTORC1) signaling pathway.

  3. Using a PDK1 (show PDPK1 ELISA Kits) conditional deletion MLL (show MLL ELISA Kits)-AF9 murine AML (show RUNX1 ELISA Kits) model, we revealed that the deletion of PDK1 (show PDPK1 ELISA Kits) prolonged the survival of AML (show RUNX1 ELISA Kits) mice by inducing LSC (show ARHGEF1 ELISA Kits) apoptosis

  4. define a specific pairing of two amino acids that creates a salt bridge between MLLT1/3 and AFF proteins that is critically important for MLL (show MLL ELISA Kits)-mediated transformation of HPCs

  5. Af9 mediates site-selective physical and functional recruitment of Rnf2 (show RNF2 ELISA Kits) to the alpha-ENaC (show SCNN1A ELISA Kits) promoter to constrain basal alpha-ENaC (show SCNN1A ELISA Kits) transcription in collecting duct cells.

  6. Impaired alphaENaC (show SCNN1A ELISA Kits) expression due to failure to inhibit Dot1a-Af9 may play an important role in the early stages of pseudohypoaldosteronism type 1 in MR(-/-) mice.

  7. We demonstrate that leukemogenic activity of MLL (show MLL ELISA Kits)-AF9 requires RUVBL2 (RuvB-like 2 (show RUVBL2 ELISA Kits)), an AAA (show AAAS ELISA Kits)+ ATPase (show DNAH8 ELISA Kits) family member that functions in a wide range of cellular processes, including chromatin remodeling and transcriptional regulation.

  8. Therefore, Dot1a and Af9 as aldosterone-downregulated targets are negative regulators of endothelin-1 (show EDN1 ELISA Kits) transcription in vitro and in vivo, and may be considered as new potential therapeutic targets of kidney injury in diabetes.

  9. It was concluded that +78/+92 of the epithelial Na+ channel alpha (show SCNN1A ELISA Kits)-subunit (show POLG ELISA Kits) represents the primary Af9 binding site involved in recruiting Dot1a to repress basal and aldosterone-sensitive Na+ channel alpha-subunit (show POLG ELISA Kits) transcription.

  10. PRC2 supports aberrant self-renewal in a mouse model of MLL (show MLL ELISA Kits)-AF9;Nras (show NRAS ELISA Kits)(G12D) acute myeloid leukemia (show BCL11A ELISA Kits).

Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 3 (MLLT3) Antigen Profile

Antigen Summary

mouse homolog regulates pattern formation during embryogenesis

Gene names and symbols associated with MLLT3

  • myeloid/lymphoid or mixed lineage-leukemia translocation to 3 homolog (Drosophila) (mllt3) antibody
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 (MLLT3) antibody
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 (Mllt3) antibody
  • 2210011H10Rik antibody
  • 2610012I03Rik antibody
  • 3830408D16Rik antibody
  • Af-9 antibody
  • Af9 antibody
  • D4Ertd321e antibody
  • fc39c11 antibody
  • wu:fc39c11 antibody
  • YEATS3 antibody
  • zgc:110210 antibody

Protein level used designations for MLLT3

protein AF-9 , ALL1-fused gene from chromosome 9 protein , YEATS domain-containing protein 3 , myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 3 , myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein , myeloid/lymphoid or mixed lineage-leukemia translocation to 3 homolog , myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein homolog , myeloid/lymphoid or mixed-lineage leukemia, translocated to, 3 , myeloid/lymphoid or mixed-lineage leukemia,translocated to, 3 (trithorax homolog, Drosophila) , translocated to, 3

GENE ID SPECIES
550517 Danio rerio
4300 Homo sapiens
521962 Bos taurus
70122 Mus musculus
481556 Canis lupus familiaris
114510 Rattus norvegicus
Did you look for something else?