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Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Additionally we are shipping Myeloperoxidase Kits (102) and Myeloperoxidase Proteins (51) and many more products for this protein.
Showing 10 out of 597 products:
Human Polyclonal Myeloperoxidase Primary Antibody for EIA, FACS - ABIN953571
Nahon, Sutton, Pessayre, Rufat, Charnaux, Trinchet, Beaugrand, Deugnier: Do genetic variations in antioxidant enzymes influence the course of hereditary hemochromatosis? in Antioxidants & redox signaling 2011
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Human Monoclonal Myeloperoxidase Primary Antibody for FACS, IF - ABIN1108346
Davey, Erber, Gatter, Mason: Immunophenotyping of acute myeloid leukemia by immuno-alkaline phosphatase (APAAP) labeling with a panel of antibodies. in American journal of hematology 1987
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Human Monoclonal Myeloperoxidase Primary Antibody for EIA, FACS - ABIN119048
Schreiber, Xiao, Jennette, Schneider, Luft, Kettritz: C5a receptor mediates neutrophil activation and ANCA-induced glomerulonephritis. in Journal of the American Society of Nephrology : JASN 2009
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Human Monoclonal Myeloperoxidase Primary Antibody for FACS - ABIN119049
Lau, Mollnau, Eiserich, Freeman, Daiber, Gehling, Brümmer, Rudolph, Münzel, Heitzer, Meinertz, Baldus: Myeloperoxidase mediates neutrophil activation by association with CD11b/CD18 integrins. in Proceedings of the National Academy of Sciences of the United States of America 2005
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Human Polyclonal Myeloperoxidase Primary Antibody for EIA, WB - ABIN953570
Banerjee, Banerjee, Ghosh, Das, Basu, Sarkar, States, Giri: Evaluation of the serum catalase and myeloperoxidase activities in chronic arsenic-exposed individuals and concomitant cytogenetic damage. in Toxicology and applied pharmacology 2010
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Human Polyclonal Myeloperoxidase Primary Antibody for IF, IHC (p) - ABIN1108338
Murao, Stevens, Ito, Huberman: Myeloperoxidase: a myeloid cell nuclear antigen with DNA-binding properties. in Proceedings of the National Academy of Sciences of the United States of America 1988
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Human Polyclonal Myeloperoxidase Primary Antibody for IHC (fro), IP - ABIN493131
Linder, Venge, Deuschl: Eosinophil cationic protein and myeloperoxidase in nasal secretion as markers of inflammation in allergic rhinitis. in Allergy 1988
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Human Polyclonal Myeloperoxidase Primary Antibody for IHC (fro), IP - ABIN493129
Taylor, Pohl, Kinkade: Unique autolytic cleavage of human myeloperoxidase. Implications for the involvement of active site MET409. in The Journal of biological chemistry 1993
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Human Polyclonal Myeloperoxidase Primary Antibody for IHC (fro), IHC (p) - ABIN115370
Dixelius, Larsson, Sasaki, Holmqvist, Lu, Engström, Timpl, Welsh, Claesson-Welsh: Endostatin-induced tyrosine kinase signaling through the Shb adaptor protein regulates endothelial cell apoptosis. in Blood 2000
Human Monoclonal Myeloperoxidase Primary Antibody for ELISA, WB - ABIN969301
Oliveira, Petrilli, Tavela, Zago, de Toledo: TNF-alpha, TNF-beta, IL-6, IL-10, PECAM-1 and the MPO inflammatory gene polymorphisms in osteosarcoma. in Journal of pediatric hematology/oncology 2007
When infiltrated with Candida albicans, smu681 myeloperoxidase-deficient embryos and sibling embryos showed similar survival. Proliferation of C. albicans was more rapid in smu681 embryos than in sibling embryos, although it was eventually suppressed.
mpx expression is controlled differently in the anterior lateral plate mesoderm and posterior lateral plate mesoderm regions and describe novel roles for etv2 (show ETV2 Antibodies) and gata1 (show GATA1 Antibodies) during primitive neutropoiesis.
myeloperoxidase and H2O2 interact directly within neutrophils at the tissue wound
Short-term atorvastatin therapy resulted in lipid lowering and anti-inflammatory activity in patients after AMI (show CFD Antibodies), independently of its effect on MPO gene expression
MPO levels were positively associated with obesity. MPO levels were positively associated with obesity indices (BMI z-score, WHtR and %BFM). Higher MPO levels were associated with higher mean arterial pressure, with nondipping and with insulin (show INS Antibodies) resistance.
High serum levels of MPO were observed in obese individuals with hs-CRP (show CRP Antibodies) above 3 mg/L, which is a classic biomarker for inflammation and cardiovascular risk
Myeloperoxidase gene polymorphism showed protective effect in Russian population diagnosed with essential hypertension.
The investigated MPO gene polymorphism is not associated with risk for the development of cervical intraepithelial neoplasia.
Myeloperoxidase and eosinophil peroxidase (show EPX Antibodies) are readily internalized by HUVEC cells where they promote cellular proliferation, migration, invasion, and stimulate angiogenesis both in vitro and in vivo.
People with myeloperoxidase 463G>A polymorphisms (AA genetic type) may have decreased lung cancer risk under dominant genetic model (meta-analysis).
concentrations of the C-reactive protein, myeloperoxidase and soluble CD40 ligand taken from peripheral vein were closely similar to the concentration found in coronary blood of ACS patients
These findings suggest that MPO functions as a mediator of novel regulatory mechanism in microcirculation, indicating the influence of MPO-induced abnormalities on RBC (show CACNA1C Antibodies) deformability under pathological stress conditions.
Report exercise-induced decline in serum concentration of myeloperoxidase in healthy smokers and smokers with COPD (show ARCN1 Antibodies).
lung MPO activity increased following induction of sepsis with CLP while siRNA treatment significantly reduced MPO activity. Liver and lung cytokine and chemokine levels in CLP-induced sepsis reduced following treatment with siRNA. These findings show a crucial pro-inflammatory role for H2S synthesized by CSE in macrophages in sepsis and suggest CSE gene silencing with siRNA as a potential therapeutic approach for this co
MPO deficiency upregulates the expression of several proinflammatory cytokines and chemokines in mouse neutrophils
Myeloperoxidase may be an important determinant of diet and inflammation on colon cancer risk via its effect on endogenous exposure to oxidants and acrolein.
Alkalinity of neutrophil phagocytic vacuoles is modulated by HVCN1 (show HVCN1 Antibodies) and has consequences for myeloperoxidase activity.
ethanol catabolism in renal tubules results in a self-perpetuating cycle of CYP2E1 (show CYP2E1 Antibodies) induction, local PTAFR (show PTAFR Antibodies) ligand formation, and neutrophil infiltration and activation that leads to myeloperoxidase-dependent oxidation and damage to kidney function.
These findings suggest that myeloperoxidase may contribute importantly to formation and rupture of CA.
Myeloperoxidase binds to RBC membranes in vitro and in vivo, is transported by RBCs to remote sites, and affects endothelial function as well as systemic vascular resistance.
MPO knockout mice were protected from high fat diet-enhanced body weight gain and insulin (show INS Antibodies) resistance. Lack of MPO also attenuated HFD-induced macrophage infiltration and expression of proinflammatory cytokines.
these results demonstrate that MPO deficiency ameliorates renal injury in the renal ablation model of chronic kidney disease in mice.
MPO contributes to the development of arthritis despite suppressing adaptive immunity in secondary lymphoid organs. This suggests distinct effects of local MPO on arthritogenic effector responses.
the role of leukocyte activation, leukocyte-derived MPO and MPO-generated oxidants on BBB (show ALMS1 Antibodies) function
Cycles presenting hyperedema weren't associated with high concentration of myeloperoxidase, intraluminal fluid, or positive cytology, making it a poor diagnostic tool of endometritis.
The analysis of synovial fluid MPO can be used as a complementary test to aid in the discrimination between infectious and noninfectious joint disease, especially when the white blood cell counts and the total protein level are inconclusive.
Results show the possibility of isolating neutrophil elastase (show ELANE Antibodies) and myeloperoxidase from the same blood sample with a sufficient yield and purity for future studies on their implication and interaction during inflammatory diseases.[elastase]
Slight elevation of MPO activity in the synovial fluid of horses with osteoarthritis and chronic non-septic arthritis, but greater elevation in septic arthritis.
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils.
, eosinophil peroxidase