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MyoD Family Inhibitor Domain Containing Proteins (MDFIC)

MDFIC product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Additionally we are shipping MDFIC Antibodies (46) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MDFIC 29969 Q9P1T7
MDFIC 16543 Q8BX65
Rat MDFIC MDFIC 362325  
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Top MDFIC Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,629.00
Details

MDFIC Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)

More Proteins for MyoD Family Inhibitor Domain Containing (MDFIC) Interaction Partners

Human MyoD Family Inhibitor Domain Containing (MDFIC) interaction partners

  1. HIC specifically interacts with HTLV-1 Tax (show CNTN2 Proteins) and negatively regulates Tax (show CNTN2 Proteins) transactivational activity by altering its subcellular distribution and stability.

  2. We demonstrate that HIC selectively interferes with Rev NLS interaction with importin beta and impedes its nuclear import and function, but does not affect Rev nuclear import mediated by transportin.

  3. These data reveal for the first time that I-mfa (show MDFI Proteins) domain proteins interact with LANA and negatively regulate LANA-mediated activation of Wnt (show WNT2 Proteins) signaling-dependent transcription by inhibiting the formation of the LANA.GSK-3beta complex.

  4. This study describes that the immune expression of HIC is cell-specific, dynamic, and identifies the HIC gene as an IL-2 (show IL2 Proteins) responsive gene.

  5. strict regulation of HIC expression at the levels of mRNA stability, translation efficiency and protein stability suggests that expression of the HIC protein and its involvement in the various pathways is required only under specific cellular conditions

Xenopus laevis MyoD Family Inhibitor Domain Containing (MDFIC) interaction partners

  1. Data indicate a role for XIC in limiting Tcf3 (show TCF3 Proteins)-dependent repression of Siamois activities that are required for goosecoid transcription and for dorsal organizer formation.

MDFIC Protein Profile

Protein Summary

This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization\; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with MDFIC

  • MyoD family inhibitor domain containing (MDFIC)
  • MyoD family inhibitor domain containing (Mdfic)
  • MyoD family inhibitor domain containing (mdfic)
  • HIC protein
  • Kdt1 protein
  • Mdfid protein

Protein level used designations for MDFIC

MyoD family inhibitor domain containing , myoD family inhibitor domain-containing protein , myoD family inhibitor domain-containing , I-mfa domain-containing protein , MyoD family inhibitor domain containing protein , kidney cell line-derived transcript 1 , kidney cell line derived transcript 1 , I-mfa domain protein XIC , XIC

GENE ID SPECIES
417774 Gallus gallus
735818 Pan troglodytes
100137388 Papio anubis
100422733 Ailuropoda melanoleuca
29969 Homo sapiens
100328794 Oryctolagus cuniculus
100192442 Sus scrofa
520530 Bos taurus
16543 Mus musculus
612042 Canis lupus familiaris
362325 Rattus norvegicus
398213 Xenopus laevis
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