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anti-Myocilin (MYOC) Antibodies

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. Additionally we are shipping Myocilin Proteins (22) and Myocilin Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MYOC 17926 O70624
MYOC 4653 Q99972
MYOC 81523 Q9R1J4
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Top anti-Myocilin Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Mouse Rabbit Un-conjugated IHC, WB 100 μL Log in to see 9 Days
$302.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA Human Eye, Retina (formalin-fixed, paraffin-embedded) stained with MYOC antibody ABIN334270 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Guinea Pig Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated WB Western Blot analysis of MYOC expression in transfected 293T cell line by MYOC monoclonal antibody (M02), clone 2B4. Lane 1: MYOC transfected lysate(57 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated WB Western blot analysis of MYOC over-expressed 293 cell line, cotransfected with MYOC Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of MYOC expression in transfected 293T cell line by MYOC monoclonal antibody (M01), clone 4F8. Lane 1: MYOC transfected lysate(57 KDa). Lane 2: Non-transfected lysate. 50 μg Log in to see 8 to 11 Days
$450.00
Details
Gibbon Rabbit Un-conjugated IHC, ELISA 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$405.17
Details

MYOC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)



Human , , ,
,
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, , , , ,
Rat (Rattus)



Top referenced anti-Myocilin Antibodies

  1. Mouse (Murine) Polyclonal MYOC Primary Antibody for IHC, WB - ABIN3022197 : Polansky, Fauss, Chen, Chen, Lütjen-Drecoll, Johnson, Kurtz, Ma, Bloom, Nguyen: Cellular pharmacology and molecular biology of the trabecular meshwork inducible glucocorticoid response gene product. in Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde 1997 (PubMed)
    Show all 5 references for ABIN3022197

More Antibodies against Myocilin Interaction Partners

Mouse (Murine) Myocilin (MYOC) interaction partners

  1. Mutated myocilin and heterozygous Sod2 (show SOD2 Antibodies) deficiency act synergistically in a mouse model of open-angle glaucoma

  2. myocilin promotes cell proliferation and resistance to apoptosis via the ERK1/2 (show MAPK1/3 Antibodies) MAPK (show MAPK1 Antibodies) signaling pathway.

  3. Myocilin binds to ErbB2 (show ERBB2 Antibodies)/ErbB3 (show ERBB3 Antibodies), activates these receptors, and affects the downstream PI3K-AKT (show AKT1 Antibodies) signaling pathway

  4. Myocilin also stimulated osteogenic differentiation of wild-type MSCs, which was associated with activation of the p38 (show CRK Antibodies), Erk1/2 (show MAPK1/3 Antibodies), and JNK (show MAPK8 Antibodies) MAP kinase (show MAPK1 Antibodies) signaling pathways

  5. We suggest that intracellular myocilin plays a role as a regulator of muscle hypertrophy pathways, acting through the components of dystrophin (show DMD Antibodies) associated protein complex.

  6. The TIGR is implicated in resistance to oxidative stress. Despite the presence of a SOD motif, which is necessary for protection in mammalian cells, the protein is not a functional SOD, but might be involved in SOD activity.

  7. TIGR is a newly identified component of the CNS glial scar that is likely to contribute to neuronal regenerative failure characteristic of the mammalian CNS.

  8. Results do not support a causative role for increased MYOC levels or the MYOC gene in steroid-induced glaucoma.

  9. Results show that myocilin and gamma-synuclein (show SNCG Antibodies) interact and as a result, myocilin's properties are changed.

  10. These data suggest that production, apparent misfolding, and nonsecretion of mutant MYOC are not, by themselves, sufficient to cause glaucoma in vivo.

Human Myocilin (MYOC) interaction partners

  1. The rate of CYP1B1 (show CYP1B1 Antibodies) mutations in Lebanese patients with primary congenital glaucoma (PCG) is lower than that reported in other Arab and Middle Eastern populations and suggests other genes are responsible.

  2. Data show that predictive genetic testing for early onset Myocilin glaucoma can facilitate early detection of disease or discharge from routine ophthalmic examinations.

  3. This study does not confirm a role for genetic variants in the MYOC, NR3C1 (show NR3C1 Antibodies) and FKBP5 (show FKBP5 Antibodies) genes in the pathogenesis of corticosteroid-induced ocular hypertension.

  4. Glaucomatous MYOC mutations activate the IL-1beta (show IL1B Antibodies)/NF-kappaB (show NFKB1 Antibodies) inflammatory stress response and the glaucoma marker SELE (show SELE Antibodies) in trabecular meshwork cells.

  5. Secondary structure prediction of the Ser341Pro MYOC gene mutation suggested that the MYOC protein was misfolded.

  6. Mutations in myoc ofactomedin domain are causative in the autosomal dominant inherited form of the prevalent ocular disorder glaucoma.

  7. A novel heterozygous missense mutation c.761CMYOC gene was identified as being co-segregated with the primary open-angle glaucoma phenotype in this family.

  8. All POAG samples underwent full sequencing of the MYOC gene, and we found a sensitivity of 100%, specificity of 99.91%, positive predictive value of 95.65%, and negative predictive value of 100% between imputation and sequencing.

  9. FAs (show FAS Antibodies), expression of fibrogenic markers, and myocilin in HTM cells. These characteristics of Hic-5 (show TGFB1I1 Antibodies) in TM cells indicate its importance in regulation of AH outflow through the TM in both normal and glaucomatous eyes.

  10. Haplotype analysis of association of the MYOC gene with primary angle-closure glaucoma in a Han Chinese population

Cow (Bovine) Myocilin (MYOC) interaction partners

  1. endoproteolytic processing might regulate the activity of myocilin; the inhibition of the processing by pathogenic mutations impairs the normal role of myocilin

Myocilin (MYOC) Antigen Profile

Protein Summary

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

Gene names and symbols associated with anti-Myocilin (MYOC) Antibodies

  • myocilin (MYOC) antibody
  • myocilin (myoc) antibody
  • myocilin (Myoc) antibody
  • myocilin, trabecular meshwork inducible glucocorticoid response (MYOC) antibody
  • myocilin, trabecular meshwork inducible glucocorticoid response (Myoc) antibody
  • AI957332 antibody
  • GLC1A antibody
  • GPOA antibody
  • JOAG antibody
  • JOAG1 antibody
  • MGC136645 antibody
  • MYOC antibody
  • myocilin antibody
  • Tigr antibody
  • zgc:136645 antibody

Protein level used designations for anti-Myocilin (MYOC) Antibodies

myocilin , trabecular meshwork-induced glucocorticoid response protein , mutated trabecular meshwork-induced glucocorticoid response protein

GENE ID SPECIES
397046 Sus scrofa
548602 Danio rerio
704406 Macaca mulatta
17926 Mus musculus
4653 Homo sapiens
81523 Rattus norvegicus
281342 Bos taurus
101087632 Felis catus
490344 Canis lupus familiaris
100008897 Oryctolagus cuniculus
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