Myocyte Enhancer Factor 2D Proteins (MEF2D)

MEF2D is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Additionally we are shipping MEF2D Antibodies (139) and MEF2D Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MEF2D 4209 Q14814
MEF2D 17261  
MEF2D 81518 O89038
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Top MEF2D Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
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Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
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HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
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Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,439.33
Details

MEF2D Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Myocyte Enhancer Factor 2D (MEF2D) Interaction Partners

Human Myocyte Enhancer Factor 2D (MEF2D) interaction partners

  1. MEF2D might be a potential biomarker during chronic inflammation-lung cancer transition, predicting the risk of lung cancer among patients with chronic respiratory diseases.

  2. HIF-1alpha (show HIF1A Proteins) transactivates MEF2D expression by binding to the MEF2D gene promoter to induce angiogenesis in colorectal tumors.

  3. MEF2D directly regulated transcription of the epithelial-mesenchymal transition driver gene ZEB1 and facilitated histone acetylation at the ZEB1 promoter in colorectal cancer cells

  4. MEF2D-BCL9 (show BCL9 Proteins)-positive patients had B-cell precursor immunophenotype and were characterized as being older in age, being resistant to chemotherapy, having very early relapse, and having leukemic blasts that mimic morphologically mature B-cell leukemia with markedly high expression of HDAC9 (show HDAC9 Proteins).

  5. These results suggest that PPARgamma (show PPARG Proteins) may exert its antiproliferative effects by negatively regulating the MEF2D in CM cells, which through upregulation of miR (show MLXIP Proteins)-122, and PPARgamma (show PPARG Proteins)/miR (show MLXIP Proteins)-122/MEF2D signaling pathway may be a novel target for treatment of CM.

  6. MEF2D overexpression participated in the growth of lung cancers and its aberrant expression may result from the reduction of tumor suppressor miR (show MLXIP Proteins)-218.

  7. MEF2D is a direct target of miR (show MLXIP Proteins)-19.

  8. We found that in malignant glioma, there is an aberrantly high expression of MEF2D, which leads to poor prognosis of malignant glioma. The downregulation of MEF2D suppresses the proliferation of malignant glioma cell lines by inducing delay of S and G2/M phases of cell cycle and promoting apoptosis.

  9. MEF2D regulates IGF-1 (show IGF1 Proteins)-induced proliferation and apoptosis in CM development, indicating IGF-1 (show IGF1 Proteins)-MEF2D pathway may be a useful target for treatment.

  10. Pokemon (show ZBTB7A Proteins) was found to enhance the migration and invasion of hepatocellular carcinoma by increasing MEF2D expression

Mouse (Murine) Myocyte Enhancer Factor 2D (MEF2D) interaction partners

  1. These findings uncover a novel role for Mef2c (show MEF2C Proteins)/d in coordinating the transcriptional network that promotes early B-cell development.

  2. This study identifies MEF2D as a critical regulator of IL-10 (show IL10 Proteins) gene expression that negatively controls microglia inflammation response and prevents inflammation-mediated cytotoxicity.

  3. Mef2d is essential for the maturation and integrity of retinal photoreceptor and bipolar cells

  4. miR (show MLXIP Proteins)-103 worked through activating AKT (show AKT1 Proteins)/mTOR (show FRAP1 Proteins) signal pathway and impairing target gene MEF2D.

  5. These findings demonstrate that broadly expressed TFs acquire specific functions through competitive recruitment to enhancers by tissue-specific Mef2d and through selective activation of these enhancers to regulate tissue-specific genes.

  6. Whereas MEF2A (show MEF2A Proteins) is absolutely required for proper myoblast differentiation, MEF2B (show MEF2B Proteins), -C, and -D were found to be dispensable for this process.

  7. A role for endogenous MEF2 (show MEF2C Proteins) factors exclusively in hormone/Fsk/cAMP-induced Nr4a1 (show NR4A1 Proteins) gene expression in mouse MA-10 Leydig cells.

  8. Oxidation of survival factor MEF2D inhibits its function, underlies oxidative stress-induced (show SQSTM1 Proteins) neurotoxicity, and may be a part of the Parkinson disease pathogenic process.

  9. Results demonstrate that coordinated alternative splicing by a single RNA binding protein modulates transcription (Mef2d) and cell signaling (Rock2 (show ROCK2 Proteins)) programs to drive tissue-specific functions (cell fusion) to promote a developmental transition.

  10. We found that Parkinson's disease -associated neurotoxins destabilize MEF2D mRNA and reduce its level in vitro and in vivo.

Cow (Bovine) Myocyte Enhancer Factor 2D (MEF2D) interaction partners

  1. Expression analysis showed that the MEF2D polymorphisms were highly correlated with MEF2D mRNA and protein levels in the longissimus dorsi muscle of Polish Holstein-Friesian bulls carrying the three different combined genotypes.

MEF2D Protein Profile

Protein Summary

This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with MEF2D

  • myocyte enhancer factor 2D (mef2d)
  • myocyte enhancer factor 2D (MEF2D)
  • MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) (MEF2D)
  • myocyte enhancer factor 2D (Mef2d)
  • C80750 protein
  • MGC145245 protein
  • sl-1 protein
  • sl1 protein
  • XMEF2D protein

Protein level used designations for MEF2D

myocyte enhancer factor 2D , MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) , myocyte-specific enhancer factor 2D-like , MADS box transcription enhancer factor 2, polypeptide D , myocyte-specific enhancer factor 2D

GENE ID SPECIES
780389 Xenopus (Silurana) tropicalis
100023326 Monodelphis domestica
100406906 Callithrix jacchus
100459204 Pongo abelii
769067 Gallus gallus
4209 Homo sapiens
17261 Mus musculus
81518 Rattus norvegicus
490413 Canis lupus familiaris
100156714 Sus scrofa
100336730 Bos taurus
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