Myomesin 1 Proteins (MYOM1)

The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. Additionally we are shipping Myomesin 1 Antibodies (49) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MYOM1 8736 P52179
Mouse MYOM1 MYOM1 17929 Q62234
Rat MYOM1 MYOM1 316740  
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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days

MYOM1 Proteins by Origin and Source

Origin Expressed in Conjugate

More Proteins for Myomesin 1 (MYOM1) Interaction Partners

Human Myomesin 1 (MYOM1) interaction partners

  1. individual subfragments of titin (show TTN Proteins) and myomesin composed of Fn type III and Ig-like domains can activate expression of two IGF-1 (show IGF1 Proteins) splice forms in cultured myoblasts

  2. Our results suggest that the downregulation of MBNL proteins should lead to the abnormal splicing of MYOM1 exon 17a in DM1 muscle.

  3. EH-myomesin levels were up-regulated at least 10 times in dilated cardiomyopathy patients compared to controls.

  4. Results identify muscle-type creatine kinase as a binding partner of a central portion of myomesin and the closely related M-protein.

Mouse (Murine) Myomesin 1 (MYOM1) interaction partners

  1. Skelemin association with alphaIIbbeta3 integrin: a structural model.

Myomesin 1 (MYOM1) Protein Profile

Protein Summary

The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50% sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with Myomesin 1 Proteins (MYOM1)

  • myomesin 1 (MYOM1)
  • myomesin 1 (Myom1)
  • myomesin 1, 185kDa (MYOM1)
  • D430047A17Rik protein
  • SKELEMIN protein

Protein level used designations for Myomesin 1 Proteins (MYOM1)

190 kDa connectin-associated protein , 190 kDa titin-associated protein , EH-myomesin , myomesin (M-protein) 1 (190kD) , myomesin 1 (skelemin) 185kDa , myomesin 1, 185kDa , myomesin family member 1 , myomesin-1 , skelemin

8736 Homo sapiens
17929 Mus musculus
316740 Rattus norvegicus
538404 Bos taurus
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