You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) Antibodies

Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Additionally we are shipping MYL2 Proteins (14) and MYL2 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MYL2 17907 P97457
MYL2 4633 P10916
MYL2 363925 P08733
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-MYL2 Antibodies at antibodies-online.com

Showing 10 out of 71 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$335.50
Details
Human Rabbit Un-conjugated IF, WB 0.1 mL Log in to see 6 to 8 Days
$308.00
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using MYL3 (1) and MYL2 (2) mouse mAb against rat fetal heart tissue lysate. 100 μL Log in to see 3 to 4 Days
$345.40
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated IHC   100 μL Log in to see 2 to 3 Days
$306.90
Details
Human Mouse Un-conjugated WB   100 μL Log in to see 10 to 11 Days
$464.29
Details
Human Mouse Un-conjugated IF, IP, ELISA, WB Detection limit for recombinant GST tagged MYL2 is 0.03 ng/ml as a capture antibody. Immunoprecipitation of MYL2 transfected lysate using anti-MYL2 monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with MYL2 MaxPab rabbit polyclonal antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with  antibody ABIN462270 followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Cow Mouse Un-conjugated EIA   0.2 mg Log in to see 6 to 8 Days
$544.50
Details
Human Mouse Un-conjugated IHC, ELISA, WB 0.05 mL Log in to see 2 to 3 Days
$481.25
Details

MYL2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
,
,
Human , , ,
,
,
,
Rat (Rattus) ,
,
,

Top referenced anti-MYL2 Antibodies

  1. Human Polyclonal MYL2 Primary Antibody for IHC (p), WB - ABIN319223 : Janiak, Zemskov, Belkin: Cell surface transglutaminase promotes RhoA activation via integrin clustering and suppression of the Src-p190RhoGAP signaling pathway. in Molecular biology of the cell 2006 (PubMed)
    Show all 3 references for ABIN319223

  2. Human Polyclonal MYL2 Primary Antibody for IHC - ABIN362086 : Rameh, Armelin: Downregulation of JE and KC genes by glucocorticoids does not prevent the G0----G1 transition in BALB/3T3 cells. in Molecular and cellular biology 1992 (PubMed)
    Show all 3 references for ABIN362086

  3. Human Polyclonal MYL2 Primary Antibody for IF, WB - ABIN197362 : Li, Wang, Jiao, Lu, Fu, Quong, Dye, Yang, Dai, Ju, Zhang, Li, Burbelo, Stanley, Pestell: Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling. in Molecular and cellular biology 2006 (PubMed)
    Show all 3 references for ABIN197362

  4. Human Monoclonal MYL2 Primary Antibody for ELISA, WB - ABIN969302 : Sachdev, Raychowdhury, Sarkar: Human fast skeletal myosin light chain 2 cDNA: isolation, tissue specific expression of the single copy gene, comparative sequence analysis of isoforms and evolutionary relationships. in DNA sequence : the journal of DNA sequencing and mapping 2004 (PubMed)
    Show all 2 references for ABIN969302

  5. Human Monoclonal MYL2 Primary Antibody for WB - ABIN2869396 : Ueda, Murata-Hori, Tatsuka, Hosoya: Rho-kinase contributes to diphosphorylation of myosin II regulatory light chain in nonmuscle cells. in Oncogene 2002 (PubMed)
    Show all 2 references for ABIN2869396

  6. Human Monoclonal MYL2 Primary Antibody for IF, IP - ABIN561897 : Gannon, Doran, Kirwan, Ohlendieck: Drastic increase of myosin light chain MLC-2 in senescent skeletal muscle indicates fast-to-slow fibre transition in sarcopenia of old age. in European journal of cell biology 2009 (PubMed)

More Antibodies against MYL2 Interaction Partners

Mouse (Murine) Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) interaction partners

  1. Treatment of mice with an AT1R (show AGTRAP Antibodies) biased ligand, acting via beta-arrestin signalling, is able to induce an increase in cardiac contractility associated with an increase in ventricular myosin light chain-2 (show MYL12B Antibodies) phosphorylation

  2. Hypertrophic cardiomyopathy associated Lys104Glu mutation in the myosin regulatory light chain causes diastolic disturbance in mice.

  3. Mammalian target of rapamycin (mTOR (show FRAP1 Antibodies)) inhibition with rapamycin improves cardiac function in type 2 diabetic mice: potential role of attenuated oxidative stress and altered contractile protein (show TNNT2 Antibodies) expression.

  4. Data indicate that NRG-1beta up-regulated the gene expressions of Nkx2.5 (show NKX2-5 Antibodies), GATA4 (show GATA4 Antibodies), alpha-actin (show ACTA2 Antibodies), MLC-2v, and ANF (show HESX1 Antibodies) in a time-dependent regulation of ErbB (show EGFR Antibodies)/ERK1/2 (show MAPK1/3 Antibodies) pathways.

  5. Results indicated that sine oculis homeobox (show PRRX1 Antibodies) 1 (Six1 (show SIX1 Antibodies)) overexpression could significantly promote the expression of fast-type muscle genes Atp2a1 (show ATP2A1 Antibodies), Srl (show SRL Antibodies), and Mylpf (show MYLPF Antibodies).

  6. High resolution characterization of myosin IIC protein tailpiece and its effect on filament assembly

  7. Accelerated cMLCK protein turnover by the ubiquitin-proteasome system underlies the transition from compensated hypertrophy to decompensated heart failure as a result of reduced phosphorylation of MLC2v.

  8. Results show that the binding force between selenium and cardiac myosin (CM), which consists of two heavy chains (MHC) and two pairs of light chains: MLC1 and MLC2, was 100 times stronger than that of daunorubicin (DNR) and CM.

  9. MLC2 isoforms play a role in tumorigenesis.

  10. Mlc2 phosphorylation regulates actin-myosin interactions in striated (show NSDHL Antibodies) muscle contraction. It is important for feedback control of calcium-dependent thin-filament activation. Dephosphorylation can play a critical role in heart failure.

Human Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) interaction partners

  1. FLNb (show FLNB Antibodies) enhances invasion of cancer cells through phosphorylation of MRLC and FAK (show PTK2 Antibodies).

  2. Ostf1b could constitutively activate the Rho kinase (show ROCK1 Antibodies) 1 (ROCK1 (show ROCK1 Antibodies)) and myosin light chain 2 (MLC2 (show MYL12B Antibodies)) signalling pathway that promotes cell migration, epithelial mesenchymal transition (EMT (show ITK Antibodies)) and cytoskeletal dynamics through stress fibre formation.

  3. Myosin regulatory light chain phosphorylation enhances cardiac beta-myosin in vitro motility under load.

  4. This review focuses on the regulatory functions of MLC-2 (show MYL9 Antibodies) in the embryonic and adult heart, with an emphasis on phosphorylation-driven actions of MLC-2v in adult cardiac muscle.

  5. Data suggest a mutation in MYL2 (amino acid substitution D94A; novel mutation in familial dilated cardiomyopathy) does affect conformation (reduced alpha-helical content) and function (reduced binding of myosin heavy chain; increased ATPase (show DNAH8 Antibodies)) of MYL2.

  6. Four novel body mass index-associated loci near the KCNQ1 (show KCNQ1 Antibodies)(rs2237892), ALDH2 (show ALDH2 Antibodies)/MYL2 (rs671, rs12229654), ITIH4 (show ITIH4 Antibodies) (rs2535633) and NT5C2 (show NT5C2 Antibodies) (rs11191580) genes are identified in East Asian-ancestry populations.

  7. Results suggest that Aurora B (show AURKB Antibodies), but not Rho/MLCK (myosin-light-chain kinase (show MYLK Antibodies)) signaling, is essential for the localization of 2P-MRLC (myosin regulatory light chains) to the midzone in dividing HeLa cells.

  8. an interplay between phosphorylation and glycosylation of MLC2 (show MYL9 Antibodies), which might be involved in the development of muscle atrophy and associated changes

  9. Newly implicated variants (MYL2, C12orf51 and OAS1 (show OAS1 Antibodies)) were found to be significantly associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes.

  10. study concludes the mutations in the last exon of MYL2 are responsible for a novel autosomal recessive lethal myosinopathy due to defects changing the C-terminal tail of the ventricular form of the myosin regulatory light chain

MYL2 Antigen Profile

Protein Summary

Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.

Gene names and symbols associated with MYL2

  • myosin light chain, phosphorylatable, fast skeletal muscle (Mylpf) antibody
  • Myosin regulatory light chain 2, ventricular/cardiac muscle isoform-like (LOC100353304) antibody
  • myosin, light chain 2, regulatory, cardiac, slow (MYL2) antibody
  • myosin, light chain 2, regulatory, cardiac, slow (Myl2) antibody
  • myosin, light chain 9, regulatory (MYL9) antibody
  • myosin, light polypeptide 2, regulatory, cardiac, slow (Myl2) antibody
  • 2410014J02Rik antibody
  • CMH10 antibody
  • Mlc-2 antibody
  • MLC-2v antibody
  • MLC2 antibody
  • Mlc2v antibody
  • Mylpc antibody
  • myosin antibody
  • regulatory antibody

Protein level used designations for MYL2

MLC2F , fast skeletal myosin light chain 2 , myosin light chain 2 , myosin regulatory light chain 2, skeletal muscle isoform , MLC-2 , MLC-2v , RLC of myosin , cardiac ventricular myosin light chain 2 , myosin regulatory light chain 2, ventricular/cardiac muscle isoform , myosin, light polypeptide 2, regulatory, cardiac, slow , regulatory light chain of myosin , slow cardiac myosin regulatory light chain 2 , cardiac myosin light chain-2 , DTNB , G1 , isoform L20-A , light polypeptide 9 , myosin regulatory light chain 2, smooth muscle major isoform , myosin regulatory light polypeptide 9 , myosin, light polypeptide 9, regulatory , smooth muscle major isoform , myosin light chain 2v , myosin light chain, phosphorylatable, cardiac ventricles , ventricular myosin regulatory light chain

GENE ID SPECIES
17907 Mus musculus
100353304 Oryctolagus cuniculus
4633 Homo sapiens
363925 Rattus norvegicus
505519 Bos taurus
396215 Gallus gallus
17906 Mus musculus
Selected quality suppliers for anti-MYL2 (MYL2) Antibodies
Did you look for something else?