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Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) ELISA Kits

Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Additionally we are shipping MYL2 Antibodies (71) and MYL2 Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MYL2 17907 P97457
MYL2 4633 P10916
Anti-Rat MYL2 MYL2 363925 P08733
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Top MYL2 ELISA Kits at antibodies-online.com

Showing 2 out of 3 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 30 pg/mL 78.13-5000 pg/mL 96 Tests Log in to see 9 to 11 Days
$700.00
Details
Mouse 3.9 pg/ml 15.6-1000 pg/mL   96 Tests Log in to see 11 to 13 Days
$910.56
Details

More ELISA Kits for MYL2 Interaction Partners

Mouse (Murine) Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) interaction partners

  1. Treatment of mice with an AT1R (show AGTRAP ELISA Kits) biased ligand, acting via beta-arrestin signalling, is able to induce an increase in cardiac contractility associated with an increase in ventricular myosin light chain-2 (show MYL12B ELISA Kits) phosphorylation

  2. Hypertrophic cardiomyopathy associated Lys104Glu mutation in the myosin regulatory light chain causes diastolic disturbance in mice.

  3. Mammalian target of rapamycin (mTOR (show FRAP1 ELISA Kits)) inhibition with rapamycin improves cardiac function in type 2 diabetic mice: potential role of attenuated oxidative stress and altered contractile protein (show TNNT2 ELISA Kits) expression.

  4. Data indicate that NRG-1beta up-regulated the gene expressions of Nkx2.5 (show NKX2-5 ELISA Kits), GATA4 (show GATA4 ELISA Kits), alpha-actin (show ACTA2 ELISA Kits), MLC-2v, and ANF (show HESX1 ELISA Kits) in a time-dependent regulation of ErbB (show EGFR ELISA Kits)/ERK1/2 (show MAPK1/3 ELISA Kits) pathways.

  5. Results indicated that sine oculis homeobox (show PRRX1 ELISA Kits) 1 (Six1 (show SIX1 ELISA Kits)) overexpression could significantly promote the expression of fast-type muscle genes Atp2a1 (show ATP2A1 ELISA Kits), Srl (show SRL ELISA Kits), and Mylpf (show MYLPF ELISA Kits).

  6. High resolution characterization of myosin IIC protein tailpiece and its effect on filament assembly

  7. Accelerated cMLCK protein turnover by the ubiquitin-proteasome system underlies the transition from compensated hypertrophy to decompensated heart failure as a result of reduced phosphorylation of MLC2v.

  8. Results show that the binding force between selenium and cardiac myosin (CM), which consists of two heavy chains (MHC) and two pairs of light chains: MLC1 and MLC2, was 100 times stronger than that of daunorubicin (DNR) and CM.

  9. MLC2 isoforms play a role in tumorigenesis.

  10. Mlc2 phosphorylation regulates actin-myosin interactions in striated (show NSDHL ELISA Kits) muscle contraction. It is important for feedback control of calcium-dependent thin-filament activation. Dephosphorylation can play a critical role in heart failure.

Human Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) interaction partners

  1. FLNb (show FLNB ELISA Kits) enhances invasion of cancer cells through phosphorylation of MRLC and FAK (show PTK2 ELISA Kits).

  2. Ostf1b could constitutively activate the Rho kinase (show ROCK1 ELISA Kits) 1 (ROCK1 (show ROCK1 ELISA Kits)) and myosin light chain 2 (MLC2 (show MYL12B ELISA Kits)) signalling pathway that promotes cell migration, epithelial mesenchymal transition (EMT (show ITK ELISA Kits)) and cytoskeletal dynamics through stress fibre formation.

  3. Myosin regulatory light chain phosphorylation enhances cardiac beta-myosin in vitro motility under load.

  4. This review focuses on the regulatory functions of MLC-2 (show MYL9 ELISA Kits) in the embryonic and adult heart, with an emphasis on phosphorylation-driven actions of MLC-2v in adult cardiac muscle.

  5. Data suggest a mutation in MYL2 (amino acid substitution D94A; novel mutation in familial dilated cardiomyopathy) does affect conformation (reduced alpha-helical content) and function (reduced binding of myosin heavy chain; increased ATPase (show DNAH8 ELISA Kits)) of MYL2.

  6. Four novel body mass index-associated loci near the KCNQ1 (show KCNQ1 ELISA Kits)(rs2237892), ALDH2 (show ALDH2 ELISA Kits)/MYL2 (rs671, rs12229654), ITIH4 (show ITIH4 ELISA Kits) (rs2535633) and NT5C2 (show NT5C2 ELISA Kits) (rs11191580) genes are identified in East Asian-ancestry populations.

  7. Results suggest that Aurora B (show AURKB ELISA Kits), but not Rho/MLCK (myosin-light-chain kinase (show MYLK ELISA Kits)) signaling, is essential for the localization of 2P-MRLC (myosin regulatory light chains) to the midzone in dividing HeLa cells.

  8. an interplay between phosphorylation and glycosylation of MLC2 (show MYL9 ELISA Kits), which might be involved in the development of muscle atrophy and associated changes

  9. Newly implicated variants (MYL2, C12orf51 and OAS1 (show OAS1 ELISA Kits)) were found to be significantly associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes.

  10. study concludes the mutations in the last exon of MYL2 are responsible for a novel autosomal recessive lethal myosinopathy due to defects changing the C-terminal tail of the ventricular form of the myosin regulatory light chain

MYL2 Antigen Profile

Antigen Summary

Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.

Gene names and symbols associated with MYL2

  • myosin light chain, phosphorylatable, fast skeletal muscle (Mylpf) antibody
  • Myosin regulatory light chain 2, ventricular/cardiac muscle isoform-like (LOC100353304) antibody
  • myosin, light chain 2, regulatory, cardiac, slow (MYL2) antibody
  • myosin, light chain 2, regulatory, cardiac, slow (Myl2) antibody
  • myosin, light chain 9, regulatory (MYL9) antibody
  • myosin, light polypeptide 2, regulatory, cardiac, slow (Myl2) antibody
  • 2410014J02Rik antibody
  • CMH10 antibody
  • Mlc-2 antibody
  • MLC-2v antibody
  • MLC2 antibody
  • Mlc2v antibody
  • Mylpc antibody
  • myosin antibody
  • regulatory antibody

Protein level used designations for MYL2

MLC2F , fast skeletal myosin light chain 2 , myosin light chain 2 , myosin regulatory light chain 2, skeletal muscle isoform , MLC-2 , MLC-2v , RLC of myosin , cardiac ventricular myosin light chain 2 , myosin regulatory light chain 2, ventricular/cardiac muscle isoform , myosin, light polypeptide 2, regulatory, cardiac, slow , regulatory light chain of myosin , slow cardiac myosin regulatory light chain 2 , cardiac myosin light chain-2 , DTNB , G1 , isoform L20-A , light polypeptide 9 , myosin regulatory light chain 2, smooth muscle major isoform , myosin regulatory light polypeptide 9 , myosin, light polypeptide 9, regulatory , smooth muscle major isoform , myosin light chain 2v , myosin light chain, phosphorylatable, cardiac ventricles , ventricular myosin regulatory light chain

GENE ID SPECIES
17907 Mus musculus
100353304 Oryctolagus cuniculus
4633 Homo sapiens
363925 Rattus norvegicus
505519 Bos taurus
396215 Gallus gallus
17906 Mus musculus
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