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anti-Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7) Antibodies

Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. Additionally we are shipping Myosin Heavy Chain 7, Cardiac Muscle, beta Kits (20) and Myosin Heavy Chain 7, Cardiac Muscle, beta Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MYH7 4625 P12883
MYH7 29557 P02564
MYH7 140781 Q91Z83
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Top anti-Myosin Heavy Chain 7, Cardiac Muscle, beta Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-Myh7 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Mouse Spleen 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC (p), WB Anti-Myosin(Skeletal, Slow) antibody (monoclonal), Western blotting WB: Rat Skeletal Muscle Tissue Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB MYH7 Antibody (N-term)  western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the MYH7 antibody detected the MYH7 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Bat Rabbit Un-conjugated IHC (p), WB Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$676.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Human Mouse Un-conjugated IHC (p), WB   100 μg Log in to see 7 to 9 Days
$463.83
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (38.1 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of mouse skeletal muscle and rat skeletal muscle cell lines, using MYH7 antibody. Immunohistochemistry of paraffin-embedded mouse lung using MYH7 antibody at dilution of 1:100 (x40 lens). 100 μL Log in to see 14 Days
$323.13
Details

MYH7 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Myosin Heavy Chain 7, Cardiac Muscle, beta Antibodies

  1. Human Monoclonal MYH7 Primary Antibody for IHC (p), WB - ABIN1108367 : Rizzo, Mazzeo, Biasiucci, Cingolani, Gigli: White electroluminescence from a microcontact-printing-deposited CdSe/ZnS colloidal quantum-dot monolayer. in Small (Weinheim an der Bergstrasse, Germany) 2008 (PubMed)

More Antibodies against Myosin Heavy Chain 7, Cardiac Muscle, beta Interaction Partners

Human Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7) interaction partners

  1. Study shows lack of phenotypic differences between MYH7- and MYBPC3 (show MYBPC3 Antibodies)-associated hypertrophic cardiomyopathy when assessed by cardiac magnetic resonance imaging.

  2. Two novel heterozygous proline substitutions located in exon 31 of MYH7 within its rod domain:c.4309G>C (p.Ala1437Pro) and c.4301G>C (p.Arg1434Pro) is causing skeletal myopathies.

  3. MYBPC3 (show MYBPC3 Antibodies) and MYH7 were the most common mutated genes, accounting for 27% of the total Hypertrophic Cardiomyopathy patients and 83% of the putative mutations in the main sarcomeric genes.

  4. MYH7 gene mutation is associated with Early-Onset Hypertrophic Cardiomyopathy.

  5. family members who carried both the MYH7-A719H and MYOZ2 (show MYOZ2 Antibodies)-L169G mutations had more severe symptoms of hypertrophic cardiomyopathy, including sudden cardiac death, than those with only the MYH7 mutation

  6. Chinese family with dual LQT1 (show KCNQ1 Antibodies) and HCM phenotypes associated with tetrad heterozygous mutations in KCNQ1 (show KCNQ1 Antibodies), MYH7, MYLK2 (show MYLK2 Antibodies), and TMEM70 (show TMM70 Antibodies) mutations.

  7. A novel heterozygous mutation (MYH7, p.Asn885Thr), and a variant of uncertain significance (TNNT2 (show TNNT2 Antibodies), p.Arg296His) were identified in 2 patients with familial hypertrophic cardiomyopathy.

  8. Multidimensional structure-function relationships in human beta-cardiac myosin from population-scale genetic variation.

  9. BNP (show BNC2 Antibodies), but not mutations in MYH7 may have a role in sudden cardiac death in children with hypertrophic cardiomyopathy

  10. 5 out of 102 (4.9%) athletes carried mutations: a heterozygous MYH7 Glu935Lys mutation, a heterozygous MYBPC3 (show MYBPC3 Antibodies) Arg160Trp mutation and another heterozygous MYBPC3 (show MYBPC3 Antibodies) Thr1046Met mutation, all of which had been reported as HCM-associated mutations

Cow (Bovine) Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7) interaction partners

  1. Tm affects the conformation of actin so as to increase the area of hydrophobic interaction between actin and myosin molecules

Pig (Porcine) Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7) interaction partners

  1. Myosin regulatory light chain phosphorylation enhances cardiac beta-myosin in vitro motility under load.

  2. Mutation analysis of MYH7 gene revealed an in-frame insertion within exon 30 of MYH7 which was perfectly associated with the disease phenotype and confirmed the dominant inheritance.

Mouse (Murine) Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7) interaction partners

  1. The promoter regions of the SERCA (show ATP2A3 Antibodies)-2A and beta-MHC genes, Atp2a2 (show ATP2A2 Antibodies) and Myh7, respectively in murine hearts after one or eight weeks of pressure overload induced by transverse aortic constriction, were evaluated.

  2. Foxo1 (show FOXO1 Antibodies) has important roles in promoting diabetic cardiomyopathy and controls beta-MHC expression in the development of cardiac dysfunction.

  3. Cooperative/allosteric effects on actomyosin crossbridge recruitment dynamics are increased by beta-MHC.

  4. Reexpression of bMHC is associated at the bMHC promoter with increased H3ac but not H3K4me3.

  5. Metabolic and myosin isoform gene expression switch in sepsis-induced myocardial depression is inducible nitric oxide synthase (show NOS2 Antibodies)-dependent.

  6. residues situated within or close to the actin-binding interface of the myosin head influence actin binding and thereby modulate actin-activated ATPase (show DNAH8 Antibodies) activity

  7. Simultaneous defects in MHC7 & TnI (show TNNI2 Antibodies) accelerate onset & progression of familial hypertrophic cardiomyopathy. Compared with single-mutant models, double-mutant mice develop severe disease & premature death, progressing directly to a dilated phenotype.

  8. the functional consequences of the mutation are fundamentally changed depending upon the context of the cardiac MHC isoform.

Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7) Antigen Profile

Protein Summary

Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.

Gene names and symbols associated with MYH7

  • myosin, heavy chain 7, cardiac muscle, beta (MYH7) antibody
  • myosin, heavy chain 16 (MYH16) antibody
  • myosin, heavy chain 7, cardiac muscle, beta (Myh7) antibody
  • myosin, heavy polypeptide 7, cardiac muscle, beta (Myh7) antibody
  • slow myosin heavy chain 1 (SM1) antibody
  • AMHC1 antibody
  • B-MHC antibody
  • beta-MHC antibody
  • CMD1S antibody
  • CMH1 antibody
  • MPD1 antibody
  • Myhc-b antibody
  • MyHC-I antibody
  • Myhcb antibody
  • myosin antibody
  • myosin-7 antibody
  • SPMD antibody
  • SPMM antibody

Protein level used designations for MYH7

cardiac muscle , chick atrial myosin heavy chain , heavy polypeptide 7 , myosin heavy chain , myosin, heavy polypeptide 7, cardiac muscle, beta , myosin-7 , masticatory myosin heavy chain 16 , beta-myosin heavy chain , myHC-beta , myhc-slow , myopathy, distal 1 , myosin heavy chain (AA 1-96) , myosin heavy chain 7 , myosin heavy chain slow isoform , myosin heavy chain, cardiac muscle beta isoform , rhabdomyosarcoma antigen MU-RMS-40.7A , beta myosin heavy chain , myHC-slow , myosin heavy chain polypeptide 7 cardiac muscle fetal , myosin heavy chain, cardiac muscle, fetal , myosin heavy chain, polypeptide 7 , type slow/beta myosin heavy chain , beta cardiac myosin heavy chain , myosin 7 , myosin heavy chain slow type 1 (beta cardiac) , MYH-beta/slow , cardiac myosin heavy chain beta

GENE ID SPECIES
395350 Gallus gallus
489862 Canis lupus familiaris
4625 Homo sapiens
29557 Rattus norvegicus
282714 Bos taurus
403807 Canis lupus familiaris
791234 Equus caballus
396860 Sus scrofa
100101566 Oryctolagus cuniculus
140781 Mus musculus
396063 Gallus gallus
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