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MYO1G is a plasma membrane-associated class I myosin (see MIM 601478) that is abundant in T and B lymphocytes and mast cells (Pierce et al., 2001 [PubMed 11544309]\; Patino-Lopez et al., 2010 [PubMed 20071333]).[supplied by OMIM, Jun 2010].. Additionally we are shipping MYO1G Antibodies (14) and MYO1G Proteins (5) and many more products for this protein.
the information on allele and genotype frequencies of HA-1 and HA-2 in a Taiwanese population
Myosin 1G is an abundant class I myosin (show MYO1C ELISA Kits) in lymphocytes whose localization at the plasma membrane depends on its ancient divergent pleckstrin (show PLEK ELISA Kits) homology (PH) domain
Study found that the unconventional myosin (show MYO6 ELISA Kits) 1g (Myo1g) motor generates membrane tension, enforces cell-intrinsic meandering search, and enhances T-DC interactions during lymph-node surveillance. Increased turning and meandering motility, as opposed to ballistic motility, is enhanced by Myo1g. Myo1g acts as a "turning motor" and generates a form of cellular "flanerie."
Myosin 1g regulates cytoskeleton plasticity, cell migration, exocytosis, and endocytosis in B lymphocytes.
Data propose that Myo1G regulates cell elasticity by deformations of the actin network at the cell cortex.
MYO1G is a plasma membrane-associated class I myosin (see MIM 601478) that is abundant in T and B lymphocytes and mast cells (Pierce et al., 2001
, minor histocompatibility antigen HA-2
, unconventional myosin-Ig
, myosin 1G