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MYO9B encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. Additionally we are shipping MYO9B Antibodies (26) and and many more products for this protein.
Data show that myo9b is localized in actin-rich ellipsoids of fish cones.
newly defined SLIT/ROBO/Myo9b/RhoA (show RHOA ELISA Kits) signaling pathway that restricts lung cancer progression and metastasis.
Our data suggest a link between MYO9B variants to an increased intestinal permeability in Crohn's disease patients.
Results does not support the association of MYO9B with schizophrenia in Chinese population.
MYO9B SNPs may influence the sub-phenotypic expression of Crohn's disease but did not find an association between these MYO9B polymorphisms and intestinal permeability in IBD.
Variants in MYO9B may be involved in acute pancreatitis
genetic variation MYO9B gene is associated with celiac disease as a protective or a risk factor
The homozygous G/G group of theMyo9B polymorphism was associated with an increased risk for Barrett's esophagus and esophageal adenocarcinoms (EAC (show CYLD ELISA Kits)) development. Also the heterozygous A/G genotype was associated with an increased risk for EAC (show CYLD ELISA Kits) development.
critical roles for Myo9b during epithelial wound healing and maintenance of tight junction integrity-key functions that may be altered in patients with Myo9b-linked inflammatory bowel disease.
we performed genetic analysis of the MYO9B gene and the IL-2 (show IL2 ELISA Kits)/IL-21 (show IL17C ELISA Kits) locus by genotyping SNPs that have been previously associated with coeliac disease or schizophrenia found no evidence for association with these two loci.
These data demonstrate an association of MYO9B with ileal CD.
This study shows that Myo9b in hematopoietic cells impacts on the induction and progression of EAE. Specifically, Myo9b regulates the onset of EAE symptoms, which correlates with immune cell proliferation and infiltration into the CNS.
we have identified Myo9b as a key regulator of spatiotemporal Rho activity in DCs with cofilin (show CFL1 ELISA Kits) as a target protein of major importance for the regulation of DC migration and T cell stimulatory capacity.
Data identify the "motorized Rho inhibitor" Myo9b as a key molecular component required for spatially coordinated cell shape changes and motility.
Myo9b functions as a motorized molecule in regions of actin polymerization and Myo9b head sequences are important for in vivo motor properties.
This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin\; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene.
, Unconventional myosin from rat 3
, myr 5
, unconventional myosin-9b
, unconventional myosin-IXb
, unconventional myosin IXb