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anti-Myosin Light Chain 2 (MYL2) Antibodies

MYL2 encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK).

list all antibodies Gene Name GeneID UniProt
Anti-Human MYL2 MYL2 4633 P10916
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More Antibodies against Myosin Light Chain 2 Interaction Partners

Human Myosin Light Chain 2 (MYL2) interaction partners

  1. Together, our results provide evidence that acetylation potentially regulates DNA-PKcs (show PRKDC Antibodies).

  2. Inhibiting PRKDC (show PRKDC Antibodies) radiosensitizes human osteosarcoma cells.

  3. these results suggest that miR (show MLXIP Antibodies)-101 sensitizes pancreatic cancer cells to gemcitabine possibly via downregulating DNA-PKcs (show PRKDC Antibodies).

  4. The bocavirus large viral nonstructural protein NS1 (show PTPN11 Antibodies) is sufficient to induce the DNA damage response and the activation of the host ATM (show ATM Antibodies), ATR (show ANTXR1 Antibodies), and DNAPK (show PRKDC Antibodies).

  5. Two siblings with hypertrophic cardiomyopathy had the pathogenic variant p.Ala13Thr variant in MYL2.

  6. the MYL2 gene on chromosome 12 is associated with serum HDL (show HSD11B1 Antibodies)-C levels in Korean men. The association was much stronger in male obese subjects and smokers than that in leaner (show CACNA1A Antibodies) nonsmoking male subjects.

  7. inhibition of DNAPKcs decreases Pgp expression and sensitizes osteosarcoma cancer stem cells to chemotherapeutic agents in vitro

  8. These results suggested potential usefulness of the phosphorylation status of XRCC4 (show XRCC4 Antibodies) Ser320 as an indicator of DNA-PK functionality in living cells.

  9. Data show that elevated expression of DNA-dependent protein kinase catalytic subunit (DNA-PKcs (show PRKDC Antibodies)), Akt3 (show AKT3 Antibodies) protein, and tumor suppressor protein p53 (p53 (show TP53 Antibodies)) in ovarian serous adenocarcinoma tissues are an indication of more advanced disease and worse prognosis.

  10. CDK2 (show CDK2 Antibodies) and DNA-PK regulate PR transcriptional activity by distinct mechanisms.

Fruit Fly (Drosophila melanogaster) Myosin Light Chain 2 (MYL2) interaction partners

  1. cycles of myosin-mediated contraction and relaxation, tightly linked to Cdc2 (show CDK1 Antibodies) and Rho kinase (show ROCK1 Antibodies) activity, are directly responsible for the axial expansion of the syncytial nuclei.

Xenopus laevis Myosin Light Chain 2 (MYL2) interaction partners

  1. Ku80 (show XRCC5 Antibodies) is susceptible to proteolytic degradation when not dimerized with Ku70 (show XRCC6 Antibodies); dimer induces DNA-PK activity; evidence that interacting domain(s) of Xenopus DNA-PKcs (show PRKDC Antibodies) is conserved so as to interact with human Ku, reconstituting a functional holoenzyme

Myosin Light Chain 2 (MYL2) Antigen Profile

Protein Summary

This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.

Gene names and symbols associated with MYL2

  • myosin, light chain 2, regulatory, cardiac, slow (MYL2) antibody
  • Myosin light chain 2 (Mlc2) antibody
  • protein kinase, DNA-activated, catalytic polypeptide (PRKDC) antibody
  • protein kinase, DNA-activated, catalytic polypeptide (prkdc) antibody
  • CG2184 antibody
  • CMH10 antibody
  • DmelCG2184 antibody
  • Dmlc2 antibody
  • DmMLC2 antibody
  • DNA-PKCS antibody
  • dnapk antibody
  • dnpk1 antibody
  • dro MLC-2 antibody
  • hyrc antibody
  • hyrc1 antibody
  • Ifm(3)99Eb antibody
  • l(3)99Eb antibody
  • LC2 antibody
  • MLC-2 antibody
  • MLC2 antibody
  • MRLC antibody
  • MYL2 antibody
  • p350 antibody
  • PRKDC antibody
  • prkdc-A antibody
  • RLC antibody
  • RLC2 antibody
  • xrcc7 antibody

Protein level used designations for MYL2

MLC-2 , MLC-2v , RLC of myosin , cardiac ventricular myosin light chain 2 , myosin light chain 2 , myosin regulatory light chain 2, ventricular/cardiac muscle isoform , myosin, light polypeptide 2, regulatory, cardiac, slow , regulatory light chain of myosin , slow cardiac myosin regulatory light chain 2 , myosin light chain 2, isoform A , CG2184-PA , Mlc2-PA , myosin LC2 , muscle-specific myosin regulatory light chain , myosin light Chain-2 , myosin regulatory light chain , myosin light chain 2, isoform B , CG2184-PB , Mlc2-PB , DNA-PK catalytic subunit , DNA-dependent protein kinase catalytic subunit , hyper-radiosensitivity of murine scid mutation, complementing 1 , p460 , protein kinase, DNA-activated, catalytic polypeptide , protein kinase catalytic subunit (DNA-dependent protein kinase) , DNA-PKcs , DNA-activated protein kinase catalytic polypeptide , DNA-dependent protein kinase catalytic subunit-like

GENE ID SPECIES
4633 Homo sapiens
43587 Drosophila melanogaster
5591 Homo sapiens
282003 Bos taurus
373602 Xenopus laevis
395376 Gallus gallus
418814 Gallus gallus
464165 Pan troglodytes
474176 Canis lupus familiaris
512740 Bos taurus
100125348 Oryctolagus cuniculus
100224961 Taeniopygia guttata
100399020 Callithrix jacchus
100586225 Nomascus leucogenys
100633457 Amphimedon queenslandica
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