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anti-Myosin Light Chain Kinase (MYLK) Antibodies

MYLK, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. Additionally we are shipping Myosin Light Chain Kinase Kits (22) and Myosin Light Chain Kinase Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MYLK 4638 Q15746
MYLK 288057  
MYLK 107589  
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Top anti-Myosin Light Chain Kinase Antibodies at antibodies-online.com

Showing 10 out of 90 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of MYLK3 Antibody (N-term) (ABIN392494) in A375 cell line lysates (35 µg/lane). MYLK3(arrow) was detected using the purified polyclonal antibody. Western blot analysis of anti-MYLK3 Antibody (N-term) (ABIN392494) in mouse heart tissue lysates (35 µg/lane). MYLK3(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Western blot analysis in K562 cell line lysates (35ug/lane) using MLCK Antibody . This demonstrates this antibody detected the MLCK protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma Western blot analysis of anti-MLCK-long Pab (ABIN392495) in mouse brain tissue lysate. MLCK-long (Arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded rat colon labeled with Anti-MLCK Polyclonal Antibody, Unconjugated (ABIN1386218) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Goat Un-conjugated EIA, WB Staining of Human Colon lysate (35µg protein in RIPA buffer) using MYLK antibody at0.03 µg/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Chicken Rabbit Un-conjugated WB Western blot analysis of MLCK1 expression in HeLa (A), SP2/0 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

MYLK Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Myosin Light Chain Kinase Antibodies

  1. Human Polyclonal MYLK Primary Antibody for EIA, IHC (p) - ABIN953458 : Al-Sadi, Ye, Dokladny, Ma: Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 3 references for ABIN953458

  2. Human Polyclonal MYLK Primary Antibody for ELISA, WB - ABIN1451970 : Potier, Chelot, Pekarsky, Gardiner, Rossier, Turnell: The human myosin light chain kinase (MLCK) from hippocampus: cloning, sequencing, expression, and localization to 3qcen-q21. in Genomics 1996 (PubMed)
    Show all 2 references for ABIN1451970

  3. Human Polyclonal MYLK Primary Antibody for IHC (p), WB - ABIN392495 : Rossi, Todd, Daniels, Bazan, Belayev: Interferon Stimulated Gene 15 upregulation precedes the development of blood brain barrier disruption and cerebral edema after traumatic brain injury in young mice. in Journal of neurotrauma 2015 (PubMed)
    Show all 2 references for ABIN392495

  4. Human Polyclonal MYLK Primary Antibody for IHC (p), WB - ABIN392494 : Rossi, Ralay Ranaivo, Patel, Chrzaszcz, Venkatesan, Wainwright: Albumin causes increased myosin light chain kinase expression in astrocytes via p38 mitogen-activated protein kinase. in Journal of neuroscience research 2011 (PubMed)
    Show all 2 references for ABIN392494

  5. Human Polyclonal MYLK Primary Antibody for EIA, IHC (p) - ABIN360382 : Cantrell: Phosphoinositide 3-kinase signalling pathways. in Journal of cell science 2001 (PubMed)

More Antibodies against Myosin Light Chain Kinase Interaction Partners

Human Myosin Light Chain Kinase (MYLK) interaction partners

  1. TKS5 (show SH3PXD2A Antibodies) and MYLK represent two mediators of invasive behavior of cancer cells that are regulated by the ZEB1 (show ZEB1 Antibodies)/miR (show MLXIP Antibodies)-200 feedback loop

  2. We speculate that the drop of the ROCK-to-MLCK ratio may occur as an attempt to compensate for the increased Rho kinase (show ROCK1 Antibodies) activity.

  3. study demonstrates that G. duodenalis-mediated disruption of villin is, at least, in part dependent on activation of myosin light chain kinase (MLCK).

  4. Gene-based association analyses shows nominal significant association with multifocal fibromuscular dysplasia for myosin light chain kinase.

  5. These structure-function studies suggest novel mechanisms for nmMLCK regulation, which may confirm MYLK as a candidate gene in inflammatory lung disease and advance knowledge of the genetic underpinning of lung-related health disparities.

  6. inhibition of p38 MAP kinase (show MAPK14 Antibodies) attenuated the histamine response in all three EC types. Inhibition of RhoA (show RHOA Antibodies), ROCK, or MLCK also prevented the histamine-induced decrease in TER (show TECR Antibodies) in HDMEC.

  7. Fine mapping of the myosin light chain kinase (MYLK) gene replicates the association with asthma in populations of Spanish descent.

  8. serum MLCK is associated with Type 2 diabetes mellitus.

  9. Data suggest that expression of MLCK, myosin light chain, and myosin heavy chain 11 (MYH11 (show MYH11 Antibodies)) is up-regulated in uterine myoma as compared to adjacent smooth muscle cells; phosphorylation/activation of MLCK appears to be involved in cell proliferation.

  10. The Smooth muscle myosin light chain kinase (MLCK) contributes to Ca(2 (show CA2 Antibodies)+) flux regulation in vascular smooth muscle (VSM) and in non-muscle cells, where cytoskeleton has been suggested to help Ca(2 (show CA2 Antibodies)+) channels trafficking.

Cow (Bovine) Myosin Light Chain Kinase (MYLK) interaction partners

  1. Histamine induces myosin light chain (MLC)phosphorylation via MYLK, suggesting regulatory role for MLC in controlling corneal epithelial permeability.

Rabbit Myosin Light Chain Kinase (MYLK) interaction partners

  1. evaluated the spatial arrangement of the catalytic/regulatory domain, three immunoglobulin-related motifs, one fibronectin-related motif, a repetitive, proline-rich segment, and, at the N-terminus, a unique F-actin-binding domain.

Mouse (Murine) Myosin Light Chain Kinase (MYLK) interaction partners

  1. telokin may play a role in attenuating constitutive myosin light chain phosphorylation

  2. MLCK is linked to timely blastocyst formation, though it is dispensable for oocyte meiotic maturation

  3. NF-kappaB (show NFKB1 Antibodies) novel partner within endothelial cells

  4. MLCK regulates cell migration in a myosin regulatory light chain phosphorylation-independent mechanism.

  5. nmMlck modulates IL-1beta (show IL1B Antibodies)-mediated downregulation of Cldn5 (show CLDN5 Antibodies) in brain microvascular endothelial cells.

  6. a prominent effect of the multifunctional microRNA-155 in endothelial cells is modulation of phenotype through alterations in RhoA, myosin light chain kinase expression, and actin cytoskeleton organization

  7. CArG element in intron 15 of the mylk1 gene is necessary for maximal expression of the 130-kDa smMLCK and that the 130-kDa smMLCK isoform is specifically required to regulate smooth muscle contractility

  8. In immune-mediated inflammatory bowel disease, tight junction dysregulation and barrier loss is induced by MLCK, but at advanced stages, barrier loss is MLCK-independent.

  9. Claudin-2 (show CLDN2 Antibodies) assumes an important role in colorectal inflammation, and furthermore implicates the involvement of MLCK in colon inflammation.

  10. involved in IL-1beta (show IL1B Antibodies)-induced increase in intestinal permeability

Myosin Light Chain Kinase (MYLK) Antigen Profile

Protein Summary

This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.

Gene names and symbols associated with MYLK

  • myosin light chain kinase (MYLK) antibody
  • myosin light chain kinase (Mylk) antibody
  • myosin, light polypeptide kinase (Mylk) antibody
  • 9530072E15Rik antibody
  • A930019C19Rik antibody
  • AAT7 antibody
  • AW489456 antibody
  • KRP antibody
  • Mlck antibody
  • MLCK1 antibody
  • MLCK108 antibody
  • MLCK210 antibody
  • MSTP083 antibody
  • MYLK1 antibody
  • SMMLCK antibody

Protein level used designations for MYLK

kinase related protein, telokin , myosin, light chain kinase , myosin light chain kinase , myosin light chain kinase, smooth muscle-like , kinase-related protein , myosin light chain kinase, smooth muscle , myosin, light polypeptide kinase , smooth muscle myosin light chain kinase , telokin , MLCK , smooth muscle myosin light chain kinase (61-kDa active fragment)

GENE ID SPECIES
460640 Pan troglodytes
488012 Canis lupus familiaris
715422 Macaca mulatta
100481263 Ailuropoda melanoleuca
4638 Homo sapiens
288057 Rattus norvegicus
338037 Bos taurus
396848 Sus scrofa
100009143 Oryctolagus cuniculus
443334 Ovis aries
396445 Gallus gallus
100714177 Cavia porcellus
107589 Mus musculus
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