Myosin Light Chain Kinase (MYLK) ELISA Kits

MYLK, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. Additionally we are shipping Myosin Light Chain Kinase Antibodies (94) and Myosin Light Chain Kinase Proteins (13) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MYLK 4638 Q15746
MYLK 288057  
MYLK 107589  
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Top Myosin Light Chain Kinase ELISA Kits at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 4.7 pg/mL 18.75-1200 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Human 0.195 ng/mL 0.78-50 ng/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$1,026.67
Details
Rat 0.057 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 15 to 17 Days
$932.09
Details
Chicken 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Rabbit 37.5 pg/mL 62.5-4000 pg/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Guinea Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Cow 78-5000 pg/mL   96 Tests Log in to see 2 to 3 Days
$867.90
Details
Monkey 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Cow
  96 Tests Log in to see 15 to 18 Days
$1,029.60
Details

Top referenced Myosin Light Chain Kinase ELISA Kits

  1. Human MYLK ELISA Kit for Sandwich ELISA - ABIN366912 : Jung, Meinzer, Montcuquet, Thachil, Château, Thiébaut, Roy, Alnabhani, Berrebi, Dussaillant, Pedruzzi, Thenet, Cerf-Bensussan, Hugot, Barreau: Yersinia pseudotuberculosis disrupts intestinal barrier integrity through hematopoietic TLR-2 signaling. in The Journal of clinical investigation 2012 (PubMed)

  2. Mouse (Murine) MYLK ELISA Kit for Sandwich ELISA - ABIN845340 : Alnabhani, Montcuquet, Biaggini, Dussaillant, Roy, Ogier-Denis, Madi, Jallane, Feuilloley, Hugot, Connil, Barreau: Pseudomonas fluorescens alters the intestinal barrier function by modulating IL-1? expression through hematopoietic NOD2 signaling. in Inflammatory bowel diseases 2015 (PubMed)

More ELISA Kits for Myosin Light Chain Kinase Interaction Partners

Human Myosin Light Chain Kinase (MYLK) interaction partners

  1. loss of MLCK contributes to the migratory properties of epithelial cells resulting from changes in cell-cell and cell-matrix adhesions, and increased epidermal growth factor receptor (show EGFR ELISA Kits) signaling.

  2. Sixty-seven experienced runners competed in a marathon race. The MLCK genotype (C37885A) of these marathoners was determined. CA heterozygotes for MLCK C37885A might present higher exercise-induced muscle damage after a marathon competition than CC counterparts.

  3. these Acute respiratory distress syndrome (ARDS)-associated MYLK cytosine-guanine dinucleotides with effect modification by ethnicity and local modified cytosine quantitative trait loci suggest that MYLK epigenetic variation and local genetic background may contribute to health disparities observed in ARDS.

  4. mechanical stress and MYLK single nucleotide polymorphism regulate MYLK alternative splicing.

  5. Rebeccamycin attenuates TNF-alpha (show TNF ELISA Kits)-induced disruption of intestinal epithelial barrier integrity by inducing claudin-5 (show CLDN5 ELISA Kits) expression and suppressing MLCK production via Chk1 (show CHEK1 ELISA Kits) activation.

  6. Data show that alterations in myosin light chain kinase activity, claudin-15 (show CLDN15 ELISA Kits) and claudin-2 (show CLDN2 ELISA Kits) expression are associated with gluten-induced symptomatology and intestinal permeability changes in diarrhea-predominant irritable bowel syndrome (IBS-D).

  7. PXR (show NR1I2 ELISA Kits) regulates the intestinal epithelial barrier during inflammation by modulating cytokine-induced MLCK expression and JNK1 (show MAPK8 ELISA Kits)/2 activation

  8. A 2-bp deletion in myosin light chain kinase (c3272_3273del, p.Ser1091*) that led to a premature stop codon have a high risk of presenting with an acute aortic dissection or rupture.

  9. In contrast to mylk2 (show MYLK2 ELISA Kits) and mylk3 (show MYLK3 ELISA Kits), mylk1 has a complex structure, and multiple protein products of the mylk1 gene are expressed in most if not all cell types. This review deals with the mylk1 gene and its protein products- multiple MLCK isoforms and noncatalytic KRP/telokin protein. [Review]

  10. Likely pathogenic variants included a TGFB2 (show TGFB2 ELISA Kits) variant in one patient and a SMAD3 (show SMAD3 ELISA Kits) variant in another. These variants have been reported previously in individuals with similar phenotypes. Variants of uncertain significance of particular interest included novel variants in MYLK and MFAP5 (show MFAP5 ELISA Kits), which were identified in a third patient

Cow (Bovine) Myosin Light Chain Kinase (MYLK) interaction partners

  1. Histamine induces myosin light chain (MLC)phosphorylation via MYLK, suggesting regulatory role for MLC in controlling corneal epithelial permeability.

Rabbit Myosin Light Chain Kinase (MYLK) interaction partners

  1. evaluated the spatial arrangement of the catalytic/regulatory domain, three immunoglobulin-related motifs, one fibronectin-related motif, a repetitive, proline-rich segment, and, at the N-terminus, a unique F-actin-binding domain.

Mouse (Murine) Myosin Light Chain Kinase (MYLK) interaction partners

  1. telokin may play a role in attenuating constitutive myosin light chain phosphorylation

  2. MLCK is linked to timely blastocyst formation, though it is dispensable for oocyte meiotic maturation

  3. NF-kappaB (show NFKB1 ELISA Kits) novel partner within endothelial cells

  4. MLCK regulates cell migration in a myosin regulatory light chain phosphorylation-independent mechanism.

  5. nmMlck modulates IL-1beta (show IL1B ELISA Kits)-mediated downregulation of Cldn5 (show CLDN5 ELISA Kits) in brain microvascular endothelial cells.

  6. a prominent effect of the multifunctional microRNA-155 in endothelial cells is modulation of phenotype through alterations in RhoA, myosin light chain kinase expression, and actin cytoskeleton organization

  7. CArG element in intron 15 of the mylk1 gene is necessary for maximal expression of the 130-kDa smMLCK and that the 130-kDa smMLCK isoform is specifically required to regulate smooth muscle contractility

  8. In immune-mediated inflammatory bowel disease, tight junction dysregulation and barrier loss is induced by MLCK, but at advanced stages, barrier loss is MLCK-independent.

  9. Claudin-2 (show CLDN2 ELISA Kits) assumes an important role in colorectal inflammation, and furthermore implicates the involvement of MLCK in colon inflammation.

  10. involved in IL-1beta (show IL1B ELISA Kits)-induced increase in intestinal permeability

Myosin Light Chain Kinase (MYLK) Antigen Profile

Antigen Summary

This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.

Gene names and symbols associated with MYLK

  • myosin light chain kinase (MYLK) antibody
  • myosin light chain kinase (Mylk) antibody
  • myosin, light polypeptide kinase (Mylk) antibody
  • 9530072E15Rik antibody
  • A930019C19Rik antibody
  • AAT7 antibody
  • AW489456 antibody
  • KRP antibody
  • Mlck antibody
  • MLCK1 antibody
  • MLCK108 antibody
  • MLCK210 antibody
  • MSTP083 antibody
  • MYLK1 antibody
  • SMMLCK antibody

Protein level used designations for MYLK

kinase related protein, telokin , myosin, light chain kinase , myosin light chain kinase , myosin light chain kinase, smooth muscle-like , kinase-related protein , myosin light chain kinase, smooth muscle , myosin, light polypeptide kinase , smooth muscle myosin light chain kinase , telokin , MLCK , smooth muscle myosin light chain kinase (61-kDa active fragment)

GENE ID SPECIES
460640 Pan troglodytes
488012 Canis lupus familiaris
715422 Macaca mulatta
100481263 Ailuropoda melanoleuca
4638 Homo sapiens
288057 Rattus norvegicus
338037 Bos taurus
396848 Sus scrofa
100009143 Oryctolagus cuniculus
443334 Ovis aries
396445 Gallus gallus
100714177 Cavia porcellus
107589 Mus musculus
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