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Myosin Light Chain Kinase 3 Proteins (MYLK3)

Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]).[supplied by OMIM, Jul 2008].. Additionally we are shipping MYLK3 Antibodies (80) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MYLK3 91807 Q32MK0
MYLK3 213435 Q3UIZ8
MYLK3 291926  
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Top MYLK3 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
$709.50
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$721.60
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$904.80
Details

MYLK3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Myosin Light Chain Kinase 3 (MYLK3) Interaction Partners

Cow (Bovine) Myosin Light Chain Kinase 3 (MYLK3) interaction partners

  1. Histamine induces myosin light chain (MLC)phosphorylation via MYLK, suggesting regulatory role for MLC in controlling corneal epithelial permeability.

Human Myosin Light Chain Kinase 3 (MYLK3) interaction partners

  1. This study demonstrates that cyclic stretch disrupts tight junctions and adherens junctions by a JNK2 (show MAPK9 Proteins), c-Src (show SRC Proteins), and MLCK (show MYLK Proteins)-dependent mechanism.

  2. Biochemical and physiological regulation of cardiac myocyte contraction by cardiac-specific myosin light chain kinase.

  3. These findings suggest that hepatitis B virus X protein disrupts stress fiber formation and triggers apoptosis via an MLCK and a PTEN-dependent pathway.

  4. Integrated cDNA expression analysis of failing human myocardia uncovered a novel protein kinase (show CDK7 Proteins), cardiac-specific myosin light chain kinase (cardiac-MLCK), which acts on MLC2v (show MYL2 Proteins).

  5. data indicate that the IL-1beta (show IL1B Proteins)-induced increase in MLCK (show MYLK Proteins) protein expression and Caco-2 TJ permeability was mediated by an increase in MLCK (show MYLK Proteins) expression and activity and by an NF-kappaB (show NFKB1 Proteins)-dependent increase in MLCK (show MYLK Proteins) gene transcription

Mouse (Murine) Myosin Light Chain Kinase 3 (MYLK3) interaction partners

  1. Data suggest that galectin-3 (show LGALS3 Proteins) in hepatocellular carcinoma cells promotes cell migration by inducing RhoA GTPase activity, activating Mlck (show MYLK Proteins), up-regulating phosphorylation of MLC2 (myosin light chain 2 (show MYL12B Proteins)), and inducing actin rearrangement.

  2. epithelial MLCK (show MYLK Proteins)-activated brush border fanning by IFN-gamma (show IFNG Proteins) promotes adherence and internalization of normally noninvasive enteric bacteria

  3. MLCK may regulate the structure and the motility of stereocilia through F-actin polymerization.

  4. Silencing TNFR2 (show TNFRSF1B Proteins), but not TNFR1 (show TNFRSF1A Proteins), resulted in restoration of epithelial tight junction (TJ) associated with decreased MLCK (show MYLK Proteins) expression.

  5. Calcium regulation of MLCK (show MYLK Proteins) facilitates GLUT4 (show SLC2A4 Proteins)-mediated glucose uptake in 3T3-L1 adipocytes.

  6. nmMLCK has a critical role in thrombin (show F2 Proteins)-induced endothelial cell inflammation and lung PMN (show TBCE Proteins) infiltration

  7. these studies show that the IL-1beta (show IL1B Proteins)-induced increase in intestinal tight junction permeability was regulated by p38 (show CRK Proteins) kinase activation of ATF-2 (show ATF2 Proteins) and by ATF-2 (show ATF2 Proteins) regulation of MLCK (show MYLK Proteins) gene activity

  8. analysis of differential contributions of MLCK (show MYLK Proteins) to signaling in smooth muscles

  9. MLCK-dependent MLC phosphorylation mediates intestinal epithelial barrier dysfunction after severe burn injury.

  10. Nonmuscle myosin light-chain kinase (show MYLK Proteins) contributes to atherosclerosis by regulating endothelial barrier function and monocyte migration via mechanisms involving not only kinase-mediated MLC phosphorylation but also Src (show SRC Proteins) activation.

MYLK3 Protein Profile

Protein Summary

Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008

Gene names and symbols associated with MYLK3

  • myosin light chain kinase 3 (MYLK3)
  • myosin light chain kinase (MYLK)
  • myosin light chain kinase (Mylk)
  • myosin light chain kinase 3 (Mylk3)
  • caMLCK protein
  • D830007F02Rik protein
  • mlck protein
  • MLCK2 protein
  • RGD1305801 protein
  • smMLCK protein

Protein level used designations for MYLK3

myosin light chain kinase 3 , Putative myosin light chain kinase 3 , cardiac-MLCK , cardiac-MyBP-C-associated Ca/CaM kinase , MLCK , myosin light chain kinase, smooth muscle , myosin, light chain kinase , myosin, light polypeptide kinase , smooth muscle myosin light chain kinase (61-kDa active fragment) , telokin , MLC kinase , cardiac-MyBP-C associated Ca/CaM kinase , putative myosin light chain kinase 3 , cardiac MLCK , cardiac-specific myosin light chain kinase

GENE ID SPECIES
415748 Gallus gallus
465143 Pan troglodytes
716132 Macaca mulatta
100056559 Equus caballus
100171951 Pongo abelii
396445 Gallus gallus
338037 Bos taurus
100714177 Cavia porcellus
91807 Homo sapiens
213435 Mus musculus
291926 Rattus norvegicus
475345 Canis lupus familiaris
526379 Bos taurus
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