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anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) Antibodies

The ERM protein family members ezrin, radixin, and moesin are cytoskeletal effector proteins linking actin to membrane-bound proteins at the cell surface. Additionally we are shipping MYLIP Proteins (7) and MYLIP Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MYLIP 29116 Q8WY64
MYLIP 218203 Q8BM54
MYLIP 306825 D3ZDI6
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Top anti-MYLIP Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-MYLIP Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: SK-MEL-2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HeLa/Jurkat cells, using MYLIP Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MYLIP Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB MYLIP Antibody (Center T126) (ABIN651508) western blot analysis in MCF-7 cell line lysates (35 µg/lane). This demonstrates the MYLIP antibody detected the MYLIP protein (arrow) MYLIP Antibody (Center T126) (ABIN651508) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the MYLIP antibody detected the MYLIP protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of IDOL staining in human heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of IDOL expression in MCF7 (A), mouse heart (B) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat lung labeled with Anti MYLIP/Idol Polyclonal Antibody, Unconjugated (ABIN1387567) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated WB MYLIP antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 14 Days
$201.19
Details

MYLIP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine) ,


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Top referenced anti-MYLIP Antibodies

  1. Chicken Polyclonal MYLIP Primary Antibody for WB - ABIN2774705 : Ohmura-Hoshino, Matsuki, Aoki, Goto, Mito, Uematsu, Kakiuchi, Hotta, Ishido: Inhibition of MHC class II expression and immune responses by c-MIR. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)

More Antibodies against MYLIP Interaction Partners

Zebrafish Myosin Regulatory Light Chain Interacting Protein (MYLIP) interaction partners

Human Myosin Regulatory Light Chain Interacting Protein (MYLIP) interaction partners

  1. Specifically, loss of IDOL increases LDLR (show LDLR Antibodies) distribution in the hepatic cell, and subsequently reduces serum LDL-C levels in dyslipidemic patients

  2. Data suggest inducible expression of IDOL is subject to robust, rapid regulation by process that is sensitive to deubiquitinase inhibition in human/mouse cell lines and primary human cells; transcriptional induction of IDOL leads to degradation of LDLR (show LDLR Antibodies).

  3. Identify USP2 (show USP2 Antibodies) as a novel regulator of lipoprotein clearance owing to its ability to control ubiquitylation-dependent degradation of the LDLR (show LDLR Antibodies) by IDOL.

  4. The study identified MARCH6 (show MARCH6 Antibodies) as a negative regulator of SREBP2 (show SREBF2 Antibodies)-mediated transcription and described an unexpected E3 circuit functionally linking MARCH6 (show MARCH6 Antibodies) and IDOL to limit uptake of low-density lipoprotein via the LDLR (show LDLR Antibodies) pathway.

  5. IDOL N342S Variant, Atherosclerosis Progression and Cardiovascular Disorders in the Italian General Population.

  6. study indicates that MYLIP p.N342S might be a pharmacogenetic marker for lipid-lowering therapy in patients with FH.

  7. Liver-specific expression of dominant-active IDOL is associated with hypercholesterolemia and a marked elevation in atherosclerotic lesions in transgenic mice.

  8. evidence for the existence of an LXR (show NR1H3 Antibodies)-IDOL-mediated internalization pathway for the LDLR (show LDLR Antibodies) that is distinct from that used for lipoprotein uptake

  9. Results show that IDOL contributes to variation in circulating levels of LDL-C.

  10. IDOL is recruited to plasma membrane by low-density lipoprotein receptor (LDLR (show LDLR Antibodies)), promotes LDLR (show LDLR Antibodies) internalization in the absence of clathrin or caveolae, and facilitates LDLR (show LDLR Antibodies) degradation by shuttling it into the multivesicular body protein-sorting pathway

Mouse (Murine) Myosin Regulatory Light Chain Interacting Protein (MYLIP) interaction partners

  1. Suggest Idol as a gatekeeper of LDLR (show LDLR Antibodies)-dependent ApoE (show APOE Antibodies) and Abeta (show APP Antibodies) clearance in the brain and a potential enzyme target for therapeutic intervention in Alzheimer disease.

  2. Estradiol-treatment led to impaired contractile function in male cardiomyocytes only, which was characterized by increased Mylip mRNA and protein levels, and decreased myosin regulatory light chain protein.

  3. These data identify the IDOL-LDLR (show LDLR Antibodies) interaction as an evolutionarily conserved mechanism for the regulation of lipid uptake and suggest that this interaction could potentially be exploited for the pharmacologic modulation of lipid metabolism.

  4. Data show that NPC1 (show NPC1 Antibodies) deficiency has a major impact on VLDL metabolism in Apoe (show APOE Antibodies)(-/-) mice through modulation of hepatic LDL-R protein levels, and a modest one on Pcsk9 (show PCSK9 Antibodies) and Idol induction.

  5. Data show that the identification of VLDLR (show VLDLR Antibodies) and ApoER2 (show LRP8 Antibodies) as Idol(Mylip) targets suggests potential roles for this LXR (show NR1H3 Antibodies)-inducible E3 ligase in the central nervous system in addition to lipid metabolism.

  6. study shows the LXR (show NR1H3 Antibodies)-Idol(Mylip)-LDLR (show LDLR Antibodies) axis defines a complementary pathway to sterol response element-binding proteins for sterol regulation of cholesterol uptake

MYLIP Antigen Profile

Protein Summary

The ERM protein family members ezrin, radixin, and moesin are cytoskeletal effector proteins linking actin to membrane-bound proteins at the cell surface. Myosin regulatory light chain interacting protein (MYLIP) is a novel ERM-like protein that interacts with myosin regulatory light chain and inhibits neurite outgrowth.

Gene names and symbols associated with MYLIP

  • myosin regulatory light chain interacting protein a (mylipa) antibody
  • myosin regulatory light chain interacting protein (MYLIP) antibody
  • myosin regulatory light chain interacting protein (mylip) antibody
  • myosin regulatory light chain interacting protein (Mylip) antibody
  • 9430057C20Rik antibody
  • IDOL antibody
  • MIR antibody
  • MYLIP antibody
  • wu:fj36b03 antibody
  • zgc:55987 antibody

Protein level used designations for MYLIP

E3 ubiquitin-protein ligase MYLIP-A , MIR-A , myosin regulatory light chain-interacting protein A , myosin regulatory light chain interacting protein , e3 ubiquitin-protein ligase MYLIP-like , E3 ubiquitin ligase-inducible degrader of the low density lipoprotein receptor , E3 ubiquitin-protein ligase MYLIP , band 4.1 superfamily member BZF1 , cellular modulator of immune recognition (c-MIR) , inducible degrader of the LDL-receptor , myosin regulatory light chain-interacting protein , idol

GENE ID SPECIES
335888 Danio rerio
462452 Pan troglodytes
549813 Xenopus (Silurana) tropicalis
702625 Macaca mulatta
100018640 Monodelphis domestica
100065647 Equus caballus
100155795 Sus scrofa
100436766 Pongo abelii
100563531 Anolis carolinensis
100586926 Nomascus leucogenys
29116 Homo sapiens
218203 Mus musculus
306825 Rattus norvegicus
494986 Xenopus laevis
420841 Gallus gallus
488230 Canis lupus familiaris
541070 Bos taurus
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