You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Myosin VIIA (MYO7A) Antibodies

MYO7A is a member of the myosin gene family. Additionally we are shipping Myosin VIIA Kits (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MYO7A 17921 P97479
MYO7A 4647 Q13402
MYO7A 266714  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Myosin VIIA Antibodies at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
REACT_Bird Rabbit Un-conjugated IF, WB   50 μg Log in to see 6 to 8 Days
$368.50
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged MYO7A is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of MYO7A expression in SKOVCAR (A), HEK293T (B) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450nm. Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti-Myosin VIIa Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged MYO7A is approximately 0.1ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Mouse Rabbit Un-conjugated WB   200 μL Log in to see 8 to 10 Days
$727.83
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.67 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 8 to 10 Days
$463.83
Details

MYO7A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , ,


, , , , , , , , , ,
Human , , ,
,
,
, , , , , , , , , , ,
Rat (Rattus) , ,


, , , , , , , , , ,

Top referenced anti-Myosin VIIA Antibodies

  1. Bird (Avian) Polyclonal Myosin VIIA Primary Antibody for IF, WB - ABIN488011 : Hasson, Heintzelman, Santos-Sacchi, Corey, Mooseker: Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1B. in Proceedings of the National Academy of Sciences of the United States of America 1995 (PubMed)
    Show all 4 references for ABIN488011

More Antibodies against Myosin VIIA Interaction Partners

Fruit Fly (Drosophila melanogaster) Myosin VIIA (MYO7A) interaction partners

  1. CK selectively interacts with the initia (show CASP8 Antibodies)tor caspase DRONC and regulates some of its non-a (show RIPK1 Antibodies)poptotic f (show CASP8 Antibodies)unctions. Results expose a conserved role for unconventional myosins in transducing caspase-d (show CASP3 Antibodies)ependent regulation of kinases.

  2. Data suggest that Crinkled acts in concert with Wingless targets to orchestrate the proper shaping of denticles in the Drosophila embryonic epidermis.

  3. Product identified as myosin VIIA.

  4. Loss of ck/myoVIIA function leads to complete deafness in Drosophila by disrupting the integrity of the scolopidia that transduce auditory signals.

  5. myosin VIIA is classified to be a high duty ratio motor

  6. kinetic behavior would allow myosin VIIa to exert and hold tension on actin filaments and, if dimerized, to function as a processive cargo transporter.

  7. domain markedly inhibits the actin (show ACTB Antibodies)-activated ATPase (show DNAH8 Antibodies) activity of tailless (show NR2E1 Antibodies) DM7A at low Ca(2 (show CA2 Antibodies)+) but not high Ca(2 (show CA2 Antibodies)+)

Zebrafish Myosin VIIA (MYO7A) interaction partners

  1. Study identified a new hair cell-specific enhancer located within Intron 2-3 of zebrafish myo7aa gene and highly conserved between species

  2. Zebrafish cone photoreceptors possess a large and well-differentiated accessory outer segment, in which the unconventional motor protein Myo7a is highly enriched.

  3. Data show that myo7a is localized in actin-rich ellipsoids of fish cones.

Mouse (Murine) Myosin VIIA (MYO7A) interaction partners

  1. MYO7A binds to and impinges on CASPASE-8 (show CASP8 Antibodies), revealing a new regulatory axis affecting RIPK1 (show RIPK1 Antibodies)>CASPASE-8 (show CASP8 Antibodies) signaling. Results expose a conserved role for unconventional myosins in transducing caspase (show CASP3 Antibodies)-dependent regulation of kinases.

  2. Myo7a interacts with integrin beta5 and selectively promotes integrin alphavbeta5-mediated cell migration

  3. Data show that myosin7a (Myo7a; sh1) deficiency causes severe retinal dysfunctions in albino sh1-/- mice.

  4. The family was found to segregate novel mutations of two different genes: myosin VIIA (MYO7A), and phosphodiesterase 6B, which causes nonsyndromic retinitis pigmentosa.

  5. the importance of MYO7A for the development and maintenance of bundle function

  6. the results support a role for MYO7A in the translocation of RPE65 (show RPE65 Antibodies), illustrating the involvement of a molecular motor (show MYO1B Antibodies) in the spatiotemporal organization of the retinoid cycle in vision.

  7. the myosin VIIa is a "slow", monomeric molecular motor (show MYO1B Antibodies) with a duty ratio of 0.6.

  8. we examine the effects of null mutation of the Ush1c gene on subcellular localization of Myo7a, Pcdh15 and Sans in the inner ear.

  9. crystal structure of MYO7A MyTH4-FERM domains in complex with the central domain (CEN) of Sans at 2.8 angstrom resolution; MyTH4-FERM/CEN complex structure provides mechanistic explanations for known deafness-causing mutations in MYO7A MyTH4-FERM

  10. Cadherin-23 (show CDH23 Antibodies), myosin VIIa and harmonin (show USH1C Antibodies) form a ternary complex and interact with phospholipids.

Human Myosin VIIA (MYO7A) interaction partners

  1. MYO7A binds to and impinges on CASPASE-8 (show CASP8 Antibodies), revealing a new regulatory axis affecting RIPK1 (show RIPK1 Antibodies)>CASPASE-8 (show CASP8 Antibodies) signaling. Results expose a conserved role for unconventional myosins in transducing caspase (show CASP3 Antibodies)-dependent regulation of kinases.

  2. The genetic correction of MYO7A mutation resulted in morphologic and functional recovery of hair cell-like cells derived from induced pluripotent stem cells from a deaf patient.

  3. Ten variants in the MYO7A gene and 34 variants in the USH2A (show USH2A Antibodies) gene were detected in Italian patients with Usher syndrome at a high detection rate.

  4. concluded that the USH1 in this family was caused by compound heterozygous mutations in MYO7A

  5. Electron microscopy revealed that myosin VIIA is a monomer in which the tail domain bends back toward the head-neck domain to form a compact structure. This compact structure is extended at high ionic strength or in the presence of Ca(2 (show CA2 Antibodies)+).

  6. Clinical phenotypes of Usher syndrome associated with MYO7A mutations.

  7. The MYO7A gene is responsible for two distinct diseases and gives evidence that the p.P1887L mutation in a homozygous state may be responsible for nonsyndromic hearing loss.

  8. new variants in genes such as MYO7A is associated with nonsyndromic deafness and vestibular dysfunction

  9. Data indicate that that CIB2 localizes to stereocilia and interacts with the USH proteins myosin VIIa and whirlin (show DFNB31 Antibodies), suggesting CIB2 is a Ca2 (show CA2 Antibodies)+-buffering protein essential for calcium homeostasis in the mechanosensory stereocilia of inner ear hair cells.

  10. Data show that AAV-mediated hMYO7A gene transfer to the mice sh1(-/-) retina is effective.

Myosin VIIA (MYO7A) Antigen Profile

Protein Summary

This gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with anti-Myosin VIIA (MYO7A) Antibodies

  • crinkled (ck) antibody
  • myosin VIIAa (myo7aa) antibody
  • myosin VIIa (LOAG_02192) antibody
  • myosin VIIA (MYO7A) antibody
  • myosin VIIA (myo7a) antibody
  • myosin 7A (Myo7A) antibody
  • myosin VIIA (Myo7a) antibody
  • 53D10S antibody
  • anon-35Bb antibody
  • BG:DS00929.11 antibody
  • br27 antibody
  • CG7595 antibody
  • ck/MyoVIIA antibody
  • D antibody
  • D2 antibody
  • DFNA11 antibody
  • DFNB2 antibody
  • DM7a antibody
  • Dm 35B antibody
  • Dmel\\CG7595 antibody
  • DmVIIa antibody
  • DMyoVIIa antibody
  • Dro35B antibody
  • ESTS:53D10S antibody
  • Hdb antibody
  • l(1)35Ca antibody
  • l(2)07130 antibody
  • l(2)35Ca antibody
  • l(2)br27 antibody
  • l35Ca antibody
  • Mhc35BC antibody
  • Myo7 antibody
  • MYO7A antibody
  • MYOVIIA antibody
  • MYU7A antibody
  • nmf371 antibody
  • NSRD2 antibody
  • NV17859 antibody
  • polka antibody
  • sh-1 antibody
  • sh1 antibody
  • stc antibody
  • stch antibody
  • USH1B antibody

Protein level used designations for anti-Myosin VIIA (MYO7A) Antibodies

CG7595-PA , CG7595-PB , ck-PA , ck-PB , lethal 27 in the black-reduced region , lethal group D2 , myosin 7a , myosin 7a heavy chain , myosin VII , myosin VIIa , myosin heavy chain at 35BC , myosin-VII , mysoin VIIa , stubby chaetae , transcription unit D , mar , mariner , myosin-VIIa , myosin VIIA , myosin-VIIa-like , myosin 7A , GLEAN_13346 , motor protein , shaker 1 , unconventional myosin-VIIa , myosin VIIA (Usher syndrome 1B (autosomal recessive, severe))

GENE ID SPECIES
34882 Drosophila melanogaster
252846 Danio rerio
9939576 Loa loa
100478193 Ailuropoda melanoleuca
100543555 Meleagris gallopavo
100551824 Anolis carolinensis
466717 Pan troglodytes
663995 Tribolium castaneum
699411 Macaca mulatta
100116446 Nasonia vitripennis
17921 Mus musculus
4647 Homo sapiens
266714 Rattus norvegicus
397373 Sus scrofa
419085 Gallus gallus
485174 Canis lupus familiaris
535092 Bos taurus
Selected quality suppliers for anti-Myosin VIIA (MYO7A) Antibodies
Did you look for something else?