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anti-Myotilin (MYOT) Antibodies

MYOT encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. Additionally we are shipping Myotilin Proteins (5) and Myotilin Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MYOT 9499 Q9UBF9
MYOT 58916 Q9JIF9
MYOT 291605  
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Top anti-Myotilin Antibodies at

Showing 10 out of 60 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Human Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated WB MYOT Antibody (Center)  western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MYOT antibody detected the MYOT protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-19455] - Immunohistochemical analysis of paraffin-embedded hepatoma, using antibody at 1:500 dilution. Western Blot: Myotilin Antibody [NBP2-19455] - Sample (30 ug of whole cell lysate) A: A549 7. 5% SDS PAGE gel, diluted at 1:3000. 0.1 mL Log in to see 6 to 9 Days
Human Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of Myotilin staining in U2OS cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibo Western blot analysis of Myotilin expression in HepG2 (A), mouse heart (B), rat heart (C) whole cell lysates. 200 μL Log in to see 9 Days
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: Myotilin Antibody [NBP1-87851] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue.Lane 6: Human tonsil tissue Immunohistochemistry-Paraffin: Myotilin Antibody [NBP1-87851] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. 0.1 mL Log in to see 8 to 11 Days
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using MYOT antibody. Immunofluorescence analysis of U2OS cell using MYOT antibody. Blue: DAPI for nuclear staining. 100 μL Log in to see 14 Days
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
Human Mouse Un-conjugated WB Western Blot analysis of MYOT expression in transfected 293T cell line by MYOT MaxPab polyclonal antibody.Lane 1: MYOT transfected lysate(54.78 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 9 Days

MYOT Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against Myotilin Interaction Partners

Pig (Porcine) Myotilin (MYOT) interaction partners

  1. Genetic association studies show that different TTID genotypes were significantly associated with carcass traits, including skin percentage, loin eye area and average skin thickness.

  2. Sequence analysis and polymorphism identification in the TTID gene associated with meat quyality traits in Sus scrofa.

Human Myotilin (MYOT) interaction partners

  1. Describe the first homozygous mutation in the myotilin gene leading to a novel, autosomal recessive subtype of myofibrillar myopathy (MFM).

  2. Analysis of myotilin turnover provides mechanistic insight into the role of myotilinopathy-causing mutations

  3. A second known pedigree with LGMD1A: this finding constitutes a gold standard of proof that mutations in the myotilin gene cause Limb-Girdle Muscular Dystrophy 1A

  4. Myotilin a thin filament-associated Z-disc protein.It binds to alpha-actinin and filamin c and is mutated in limb girdle muscular dystrophy 1A (LGMD1A).myotilin binds F-actin and prevents filament disassembly induced by Latrunculin A

  5. Mutations in myotilin cause MFM; exon 2 of MYOT is a hotspot for mutations; peripheral neuropathy, cardiomyopathy, and distal weakness greater than proximal weakness are part of the spectrum of myotilinopathy; not all cases have a limb-girdle phenotype

  6. Our findings provide evidence for a novel connection between the Z-disc protein myotilin and the sarcolemma via filamins and beta1 integrins.

  7. The function of the myotilin protein is studied with regards its actin-organizing properties.

  8. A novel mutation in the myotilin gene results in the clinical and pathologic phenotype termed "spheroid body myopathy." Mutations in this gene also cause limb-girdle muscular dystrophy 1A and are associated with myofibrillar myopathy.

  9. Mutations within the MYOT gene are not a cause for Vocal Cord and Pharyngeal Weakness with Distal Myopathy (VCPDM (show MATR3 Antibodies)).

  10. multigenerational French family in which gene sequencing identified a S60F myotilin mutation in all patients with full penetrance despite very late onset

Mouse (Murine) Myotilin (MYOT) interaction partners

  1. Myotilin does not have a significant influence on muscle mass, muscle fiber size, or regulation of muscle contraction. Alternatively, compensatory over-expressions of other elements may compensate for the lack of myotilin.

  2. features suggest an important role for myotilin in sarcomere organization.

  3. either myotilin does not participate in muscle development and basal function maintenance or other proteins serve as structural and functional compensatory molecules when myotilin is absent

  4. In single-transgenic mutant mice, double-transgenic mice overexpressing myotilin showed more severe muscle degeneration, enhanced myofibrillar aggregation, and earlier onset of aggregation.

Myotilin (MYOT) Antigen Profile

Protein Summary

This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Gene names and symbols associated with anti-Myotilin (MYOT) Antibodies

  • myotilin (MYOT) antibody
  • myotilin-like (LOC100855693) antibody
  • myotilin (LOC100226120) antibody
  • titin immunoglobulin domain protein (myotilin) (ttid) antibody
  • myotilin (Myot) antibody
  • 5530402I04Rik antibody
  • LGMD1 antibody
  • LGMD1A antibody
  • MFM3 antibody
  • MYOT antibody
  • Ttid antibody
  • TTOD antibody

Protein level used designations for anti-Myotilin (MYOT) Antibodies

titin immunoglobulin domain protein , myotilin , titin immunoglobulin domain protein (myotilin) , 57 kDa cytoskeletal protein , myofibrillar titin-like Ig domains protein , titan-like protein

507884 Bos taurus
100101550 Sus scrofa
100855693 Canis lupus familiaris
100072634 Equus caballus
462087 Pan troglodytes
610400 Canis lupus familiaris
100024740 Monodelphis domestica
100226120 Taeniopygia guttata
100344050 Oryctolagus cuniculus
100400348 Callithrix jacchus
100447797 Pongo abelii
100583498 Nomascus leucogenys
416299 Gallus gallus
549913 Xenopus (Silurana) tropicalis
9499 Homo sapiens
58916 Mus musculus
291605 Rattus norvegicus
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