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The transcript produced from MTPN is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. Additionally we are shipping Myotrophin Kits (24) and Myotrophin Proteins (19) and many more products for this protein.
Showing 10 out of 27 products:
Chicken Polyclonal MTPN Primary Antibody for WB - ABIN2785128
Xiong, Liu, Yan, Silver, Yang, Chen, Chen, Verstovsek, Wang, Prchal, Yang: An unconventional antigen translated by a novel internal ribosome entry site elicits antitumor humoral immune reactions. in Journal of immunology (Baltimore, Md. : 1950) 2006
Show all 2 references for ABIN2785128
T allele of rs17168525 in the 3'-UTR (show UTS2R Antibodies) of myotrophin influence the level of myotrophin protein by interfering with let-7 binding.The T allele of MTPN rs17168525 is not associated with the left ventricular hypertrophy risk in essential hypertension patients.
myotrophin/V-1 is a regulatory protein for modulating the levels of activated NFkappaB dimers.
a novel internal ribosome entry site-mediated mechanism may be responsible for the translation of unconventional self-Ag MPD6 in response to IFN-alpha (show IFNA Antibodies) stimulation.
Our data argue that a large pool of freely diffusing, inactive capping protein (CP:V-1) feeds, via CARMIL (show LRRC16A Antibodies)-driven complex exchange, the formation of weak-capping complexes (CP:CARMIL) at the plasma membrane of protruding edges.
miR (show MLXIP Antibodies)-375 enhances palmitate-induced lipoapoptosis in insulin (show INS Antibodies)-secreting NIT-1 (show NIT1 Antibodies) cells (a NOD-derived beta-cell line) by repressing myotrophin (V1) protein expression.
myotrophin has a role in myocardial hypertrophy and heart failure
actin-capping protein (show TMOD4 Antibodies) binds to the filament barbed end of myotrophin/V-1
Rat neonatal cardiac myocytes incubated with myotrophin showed an increase in c-myc, c-fos, and c-jun RNA levels and an increase in connexin 43, atrial natriuretic factor, skeletal alpha-actin, and total myosin transcript levels.
The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease.
, granule cell differentiation protein
, protein V-1
, V-1 protein
, growth factor
, stimulates myocyte growth
, V1 protein homologue