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The transcript produced from MTPN is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. Additionally we are shipping Myotrophin Antibodies (31) and Myotrophin Proteins (19) and many more products for this protein.
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T allele of rs17168525 in the 3'-UTR (show UTS2R ELISA Kits) of myotrophin influence the level of myotrophin protein by interfering with let-7 binding.The T allele of MTPN rs17168525 is not associated with the left ventricular hypertrophy risk in essential hypertension patients.
myotrophin/V-1 is a regulatory protein for modulating the levels of activated NFkappaB dimers.
a novel internal ribosome entry site-mediated mechanism may be responsible for the translation of unconventional self-Ag MPD6 in response to IFN-alpha (show IFNA ELISA Kits) stimulation.
Our data argue that a large pool of freely diffusing, inactive capping protein (CP:V-1) feeds, via CARMIL-driven complex exchange, the formation of weak-capping complexes (CP:CARMIL) at the plasma membrane of protruding edges.
miR (show MLXIP ELISA Kits)-375 enhances palmitate-induced lipoapoptosis in insulin (show INS ELISA Kits)-secreting NIT-1 (show NIT1 ELISA Kits) cells (a NOD-derived beta-cell line) by repressing myotrophin (V1) protein expression.
myotrophin has a role in myocardial hypertrophy and heart failure
actin-capping protein (show TMOD4 ELISA Kits) binds to the filament barbed end of myotrophin/V-1
Rat neonatal cardiac myocytes incubated with myotrophin showed an increase in c-myc, c-fos, and c-jun RNA levels and an increase in connexin 43, atrial natriuretic factor, skeletal alpha-actin, and total myosin transcript levels.
The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease.
, granule cell differentiation protein
, protein V-1
, V-1 protein
, growth factor
, stimulates myocyte growth
, V1 protein homologue