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anti-Myotubularin Related Protein 2 (MTMR2) Antibodies

MTMR2 is a member of the myotubularin family of phosphoinositide lipid phosphatases. Additionally we are shipping Myotubularin Related Protein 2 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MTMR2 8898 Q13614
MTMR2 77116 Q9Z2D1
MTMR2 315422  
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Top anti-Myotubularin Related Protein 2 Antibodies at antibodies-online.com

Showing 10 out of 39 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated FACS, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane... 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated ELISA, WB MTMR2 monoclonal antibody (M03), clone 4G6 Western Blot analysis of MT... Detection limit for recombinant GST tagged MTMR2 is approximately 0.3n... 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: U87-MG 7.5% SDS PAGE a... 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated WB Western Blot analysis of MTMR2 expression in transfected 293T cell lin... 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 6 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (fp), WB 100 μL Log in to see 6 to 11 Days
$485.71
Details
Human Mouse Un-conjugated FACS   100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.67 KDa) . 50 μL Log in to see 9 Days
$298.57
Details

MTMR2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
, ,
Mouse (Murine) , , ,

Rat (Rattus) , , ,
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Top referenced anti-Myotubularin Related Protein 2 Antibodies

  1. Human Monoclonal MTMR2 Primary Antibody for ELISA, WB - ABIN563874 : Bolis, Coviello, Visigalli, Taveggia, Bachi, Chishti, Hanada, Quattrini, Previtali, Biffi, Bolino: Dlg1, Sec8, and Mtmr2 regulate membrane homeostasis in Schwann cell myelination. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 (PubMed)

More Antibodies against Myotubularin Related Protein 2 Interaction Partners

Human Myotubularin Related Protein 2 (MTMR2) interaction partners

  1. we identified a novel mutation in MTMR2 in a family with CMT4B1 and myelin outfoldings

  2. these results reveal that MTMR2 compartmentalization and potential subsequent effects on endosome maturation and endosome signaling are dynamically regulated through MAPK (show MAPK1 Antibodies)-mediated differential phosphorylation events.

  3. Mutations in LITAF (show LITAF Antibodies), RAB7 (show RAB7B Antibodies), LMNA (show LMNA Antibodies), and MTMR2 genes are rare in Chinese Charcot-Marie-Tooth disease (CMT) patients.

  4. Novel mutations in the PRX (show PRDX6 Antibodies) and the MTMR2 genes are responsible for unusual Charcot-Marie-Tooth disease phenotypes.

  5. MTMR2 phosphorylation is likely to be a critical mechanism by which MTMR2 access to its lipid substrate(s) is temporally and spatially regulated, thereby contributing to the control of downstream endosome maturation events.

  6. MTMR2 shares similar phosphatase activity and substrate specificity than its homologous proteins MTM1 (show MTM1 Antibodies) and MTMR3 (show MTMR3 Antibodies)

  7. REVIEW : MTMR2 belongs to the myotubularin (show MTM1 Antibodies) family of phosphoinositides phosphatases

  8. Loss of MTMR2, by decreasing Schwann cells proliferation and survival, may impair the first stages of myelination of the peripheral nervous system

  9. REVIEW : MTMR2 and homologous proteins are mutated in several neuromuscular diseases

  10. A phylogenetic study revealing co-evolution of myotubularins with PI 3 (show PI3 Antibodies)-kinase class III complex

Mouse (Murine) Myotubularin Related Protein 2 (MTMR2) interaction partners

  1. Mtmr2 and Mtmr13 depend upon each other to achieve wild-type levels of protein expression. Mtmr2 stabilizes Mtmr13 on membranes, indicating that the Mtmr13 pseudophosphatase is regulated by its catalytically active binding partner.

  2. data indicate that Mtmr2 and Mtmr13/Sbf2 play critical roles in the sorting and modulation of cellular signalling which are likely to be disturbed in Charcot-Marie-Tooth disease type 4B

  3. Here we provide strong evidence that Mtmr2 and Fig4 (show FIG4 Antibodies) functionally interact in both Schwann cells and neurons, and we reveal for the first time a role of Mtmr2 in neurons in vivo

  4. Loss of phosphatase activity in myotubularin-related protein 2 is associated with Charcot-Marie-Tooth disease type 4B1

  5. Mtmr2 forms a dimer and the C-terminal coiled-coil is responsible for homodimerization, in addition to membrane association

  6. Schwann cell-autonomous loss of Mtmr2-Dlg1 (show DLG1 Antibodies) interaction dysregulates membrane homeostasis in the paranodal region, thereby producing outfolding and recurrent loops of myelin.

  7. Loss of Mtmr2 in Schwann cells, but not in motor neurons, is both sufficient and necessary to cause Charcot-Marie-Tooth type neuropaathy.

  8. Interaction of Discs large 1 (Dlg1 (show DLG4 Antibodies)) with the Sec8 (show EXOC4 Antibodies) exocyst component promotes membrane addition, whereas with Mtmr2, negatively regulates membrane formation.

Myotubularin Related Protein 2 (MTMR2) Antigen Profile

Protein Summary

This gene is a member of the myotubularin family of phosphoinositide lipid phosphatases. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene.

Gene names and symbols associated with MTMR2

  • myotubularin related protein 2 (MTMR2) antibody
  • myotubularin related protein 2 (Mtmr2) antibody
  • myotubularin related protein 2 (mtmr2) antibody
  • 6030445P13Rik antibody
  • CMT4B antibody
  • CMT4B1 antibody
  • DKFZp459I198 antibody
  • MTMR2 antibody
  • zgc:153915 antibody

Protein level used designations for MTMR2

myotubularin related protein 2 , myotubularin-related protein 2 , myotubularin-related protein 2-like , Myotubularin-related protein 2

GENE ID SPECIES
100080246 Ornithorhynchus anatinus
100352381 Oryctolagus cuniculus
100473901 Ailuropoda melanoleuca
451498 Pan troglodytes
606918 Canis lupus familiaris
699703 Macaca mulatta
100174264 Pongo abelii
100404569 Callithrix jacchus
8898 Homo sapiens
77116 Mus musculus
315422 Rattus norvegicus
536810 Bos taurus
418992 Gallus gallus
100518140 Sus scrofa
30644 Danio rerio
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