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Myotubularin Related Protein 6 Proteins (MTMR6)

Phosphatase that acts on lipids with a phosphoinositol headgroup. Additionally we are shipping MTMR6 Antibodies (30) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MTMR6 9107 Q9Y217
MTMR6 219135 Q8VE11
Rat MTMR6 MTMR6 305935  
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Top MTMR6 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MTMR6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Myotubularin Related Protein 6 (MTMR6) Interaction Partners

Rhesus Monkey Myotubularin Related Protein 6 (MTMR6) interaction partners

  1. Luciferase reporter assays confirm MTMR6 as a direct miR (show MYLIP Proteins)-190b target; miR (show MYLIP Proteins)-190b-mediated MTMR6 downregulation suggests an important mechanism that could keep infected cells in an activated state, thereby promoting viral replication.

Human Myotubularin Related Protein 6 (MTMR6) interaction partners

  1. MTMR6, which dephosphorylates PI(3 (show PI3 Proteins))P to PI, and its binding partner MTMR9 (show MTMR9 Proteins), are required for macropinocytosis.

  2. results indicate that the cellular localization of MTMR6 is regulated by Rab1B (show RAB1B Proteins) in the early secretory and autophagic pathways

  3. investigation of MTM1 (show MTM1 Proteins) and MTMR6 and finding that they use PtdIns(3,5)P2 in addition to PtdIns3P as a substrate in vitro

  4. Identification of myotubularin (show MTM1 Proteins) as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein (show MTMR12 Proteins), 3-PAP (show MTMR12 Proteins).

  5. Data show that KCa3.1 (show KCNN4 Proteins), which is critical for Ca2 (show CA2 Proteins)+ influx in reactivated naive T cells and central memory T cells, requires phosphatidylinositol-3 phosphatase for activation and is inhibited by PI(3 (show PI3 Proteins))P phosphatase myotubularin-related protein 6 (MTMR6).

  6. MTMR9 (show MTMR9 Proteins) greatly enhances the functions of MTMR6

MTMR6 Protein Profile

Protein Summary

Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells (By similarity).

Gene names and symbols associated with MTMR6

  • myotubularin related protein 6 (mtmr6)
  • myotubularin related protein 6 (MTMR6)
  • myotubularin related protein 6 (LOC100338397)
  • myotubularin related protein 6 (Mtmr6)
  • 4022440C11Rik protein
  • AI428804 protein
  • AU041072 protein
  • wu:fi04a11 protein
  • zgc:55289 protein

Protein level used designations for MTMR6

myotubularin-related protein 6 , myotubularin related protein 6 , myotubularin-related protein 6-like

GENE ID SPECIES
327346 Danio rerio
418938 Gallus gallus
452496 Pan troglodytes
477336 Canis lupus familiaris
540589 Bos taurus
709118 Macaca mulatta
100058883 Equus caballus
100173697 Pongo abelii
100338397 Oryctolagus cuniculus
100380604 Salmo salar
100385223 Callithrix jacchus
100547050 Meleagris gallopavo
9107 Homo sapiens
219135 Mus musculus
305935 Rattus norvegicus
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