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MTMR8 encodes a member of the myotubularin-related family and is part of the MTMR6 subgroup. Additionally we are shipping MTMR8 Antibodies (30) and many more products for this protein.
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Here, the crystal structure of the phosphatase domain of MTMR8 is reported.
East African population that gave rise to non-Africans underwent a selective sweep affecting the subcentromeric region where MTMR8 is located
MTMR7 (show MTMR7 Proteins) forms a complex with MTMR9 (show MTMR9 Proteins) and dephosphorylates phosphatidylinositol 3-phosphate and Ins (show INS Proteins)(1,3)P2 in neuronal cells.
This gene encodes a member of the myotubularin-related family and is part of the MTMR6 subgroup. Family members are dual-specificity phosphatases and the encoded protein contains a phosphoinositide-binding domain (PID) and a SET-interacting domain (SID). Defects in other family members have been found in myotubular myopathic diseases.
myotubularin related protein 9
, myotubularin related protein 8
, myotubularin related protein 8-like
, myotubularin-related protein 8-like
, myotubularin-related protein 8
, myotubularin-related protein 9