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MTMR9 encodes a myotubularin-related protein that is atypical to most other members of the myotubularin-related protein family because it has no dual-specificity phosphatase domain. Additionally we are shipping MTMR9 Antibodies (28) and MTMR9 Kits (6) and many more products for this protein.
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Polymorphism of rs2293855 in MTMR9 is associated with measures of glucose tolerance, indices of insulin (show INS Proteins) secretion and indices of insulin (show INS Proteins) sensitivity.
MTMR6 (show MTMR6 Proteins), which dephosphorylates PI(3 (show PI3 Proteins))P to PI, and its binding partner MTMR9, are required for macropinocytosis.
Our data suggest that genetic variations in the FTO (show FTO Proteins), SCG3 (show SCG3 Proteins) and MTMR9 genes independently influence the risk of metabolic syndrome.
Association of single-nucleotide polymorphisms in MTMR9 gene with obesity.
MTMR9 greatly enhances the functions of MTMR6 (show MTMR6 Proteins)
MTMR7 (show MTMR7 Proteins) forms a complex with MTMR9 and dephosphorylates phosphatidylinositol 3-phosphate and Ins (show INS Proteins)(1,3)P2 in neuronal cells.
This gene encodes a myotubularin-related protein that is atypical to most other members of the myotubularin-related protein family because it has no dual-specificity phosphatase domain. The encoded protein contains a double-helical motif similar to the SET interaction domain, which is thought to have a role in the control of cell proliferation. In mouse, a protein similar to the encoded protein binds with MTMR7, and together they dephosphorylate phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate.
myotubularin related protein 9
, myotubularin related protein 8
, myotubularin-related protein 9
, myotubularin-related protein 9-like