Myxovirus (Influenza Virus) Resistance 1, Interferon-Inducible Protein p78 (Mouse) Proteins (MX1)

In mouse, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. Additionally we are shipping MX1 Antibodies (117) and MX1 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MX1 24575  
MX1 17857 P09922
MX1 4599 P20591
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top MX1 Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,890.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 2 to 3 Days
$510.36
Details

MX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Mouse (Murine)

Human , , ,
, ,

More Proteins for Myxovirus (Influenza Virus) Resistance 1, Interferon-Inducible Protein p78 (Mouse) (MX1) Interaction Partners

Mouse (Murine) Myxovirus (Influenza Virus) Resistance 1, Interferon-Inducible Protein p78 (Mouse) (MX1) interaction partners

  1. the enhanced influenza virus susceptibility of CAST/EiJ mice can be explained by minor alterations in the MX1 restriction factor that negatively affect its enzymatic activity and reduce its half-life

  2. Data indicate that Mx protein (show MX2 Proteins) as host defense peptide can be potentiated for improving influenza vaccine efficacy.

  3. Mouse Mx1 was shown to be essential for interferon (show IFNA Proteins) type I-dependent protective immunity against primary influenza. (Review)

  4. In Mx1-intact mice with weakened resistance due to deficiencies in Mavs (show MAVS Proteins) and Tlr7 (show TLR7 Proteins), an elevated respiratory bacterial burden was found.

  5. Functional Comparison of Mx1 from Two Different Mouse Species Reveals the Involvement of Loop L4 in the Antiviral Activity against Influenza A Viruses.

  6. we show that, very unexpectedly, congenic D2-Mx1(r/r) mice carrying the wild-type Mx1 gene from the A2G strain are not fully protected against lethal influenza virus infections

  7. dysregulated gene transcriptional activity corresponded to persistent induction of cytokine/chemokines and recruitment of cytokine-producing cells that promote inflammation in B6-Mx1(-/-) mouse lungs.

  8. Mice with a functional Mx1 generate a strong antiviral state by downregulating key modulator molecules associated with influenza virus lethality.

  9. functional Mx1 did not alter olfactory bulb invasion by virus but attenuated illness compared to knockout Mx1 mice

  10. nuclear MxA suppresses the influenza virus transcription by interacting not only with RNA polymerase subunit PB2 but also with influenza NP

Human Myxovirus (Influenza Virus) Resistance 1, Interferon-Inducible Protein p78 (Mouse) (MX1) interaction partners

  1. studied the susceptibility of Vaccinia virus and Cowpox viruses to MxA antiviral action, and concluded that these viruses are not affected by the antiviral action of MxA

  2. Here, the authors show that for North African patients with chronic hepatitis, MX1 gene variation at position -123 may influence the outcome of hepatitis B virus infection but not hepatitis B virus infection.

  3. the data identify MxA as a novel stimulator of BMP4 (show BMP4 Proteins) and BMP9 (show GDF2 Proteins) transcriptional signaling, and suggest it to be a candidate IFN-alpha (show IFNA Proteins)-inducible mechanism that might have a protective role against development of pulmonary arterial hypertension and other vascular diseases.

  4. This study provides Class II evidence that immunohistochemistry-detected sarcoplasmic MxA expression accurately identifies patients with dermatomyositis (DM): sarcoplasmic MxA expression detected by immunohistochemistry is a more sensitive marker of DM than the conventional hallmarks

  5. A significant association was observed between MX1 -88G/T SNP and susceptibility to systemic lupus erythematosus

  6. Study shows different levels of expression of MxA in each breast cancer subtype and its close relationship with tumor-infiltrating lymphocytes. MxA protein expression was higher in triple-negative breast cancer and correlated with a higher histologic grade.

  7. This study demonstrated that MxA mRNA expression of interferon beta (show IFNB1 Proteins) response in multiple sclerosis patients.

  8. Transient dimerization of human MxA promotes GTP (show AK3 Proteins) hydrolysis.The GTPase (show RACGAP1 Proteins) domains of Mx proteins dimerize transiently to facilitate catalysis.

  9. polymorphism at position -88 in the MxA promoter region might be a potential biomarker to predict HCV progression toward end-stage fibrosis and response to IFN-based therapy in chronic hepatitis C patients.

  10. data suggest that, during infection, a fraction of MxA disassembles into dimers that bind to NP synthesized following primary transcription in the cytoplasm, thereby preventing viral replication

Pig (Porcine) Myxovirus (Influenza Virus) Resistance 1, Interferon-Inducible Protein p78 (Mouse) (MX1) interaction partners

  1. The deletion/insertion polymorphism in exon 14 of the Mx1 gene, which causes a frame shift, showed no significant association with growth or viremia after PRRSV infection.

  2. the SINE insertion polymorphism at site -547 of the MX1 gene promoter region is a potential DNA marker for porcine reproductive and respiratory syndrome resistance

  3. Overexpression of porcine Mx1 induce a robust immune response against foot-and-mouth disease virus.

  4. Studied the effects of porcine Mx1 protein on FMDV and BVDV replication by measuring viral reverse transcriptase activity at various time intervals.

  5. Polymorphisms in Mx1 are significantly associated with immunological traits in Landrace piglets and have potential application value for marker-assisted selection of pig breeding with disease resistance.

  6. Porcine Mx1 protein inhibits replication of influenza A virus, and impairs the traffic of the endocytic vesicles to the late endosomes.

  7. The 11-bp deletion Mx1 mutant is lacking antiviral activity able to contribute to the interference of influenza virus replication.

  8. Data showed that there were abundant MX1 gene polymorphisms in all pig breeds.

  9. Sequencing of the 332-bp MX1 promoter region identified 15 substitutions and insertions at three positions in 21 pigs from 15 breeds, in which nine genotypes were classified.

Cow (Bovine) Myxovirus (Influenza Virus) Resistance 1, Interferon-Inducible Protein p78 (Mouse) (MX1) interaction partners

  1. MX1-a, MX1B and MX2 (show MX2 Proteins) are affected by the type I IFN pathway during pregnancy and are involved in an immune response to protect the mother and fetus

  2. The replication levels of foot-and-mouth disease virus RNA were promoted by silencing bovine Mx1.

  3. Overexpression of bovine Mx1 protein inhibits the replication of foot-and-mouth disease virus.

  4. Data indicate that the expression profiles of ISG15 (show ISG15 Proteins), MX1, MX2 (show MX2 Proteins), and OAS1 (show OAS1 Proteins) could be a useful diagnostic biomarker of gestation.

  5. The proximal GC boxes were found to be essential for IFN response in the bovine Mx1 promoter with the deletion mutants.

  6. Mx1 is cytoplasmic. Mx1B is mainly nuclear. An Arg-rich nuclear localization signal was found in 27 AAs (show FGD1 Proteins) specific for Mx1B. N-terminus-deleted Mx1B is only cytoplasmic. The deleted-Mx1B-expressing cells had positive antiviral activity against VSVDeltaG*-G.

  7. A new bovine Mx gene (designated Mx1B) was isolated from the endometrial cDNA library of the early pregnant cow.

MX1 Protein Profile

Protein Summary

In mouse, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. The protein encoded by this gene is similar to the mouse protein as determined by its antigenic relatedness, induction conditions, physicochemical properties, and amino acid analysis. This cytoplasmic protein is a member of both the dynamin family and the family of large GTPases. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with MX1

  • myxovirus (influenza virus) resistance 1 (Mx1)
  • myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) (MX1)
  • AI893580 protein
  • IFI-78K protein
  • IFI78 protein
  • MX protein
  • Mx-1 protein
  • Mx1-b protein
  • Mx1B protein
  • MxA protein
  • OGTPBP protein
  • ONBP protein

Protein level used designations for MX1

Myxovirus (influenza) resistance homolog of murine Mx (also interferon-inducible protein IFI78) , Myxovirus (influenza) resistance, homolog of murine Mx (also interferon-inducible protein IFI78) , interferon-induced GTP-binding protein Mx1 , myxoma resistance protein 1 , myxovirus resistance protein 1 , myxovirus (influenza) resistance 1 polypeptide , interferon-regulated resistance GTP-binding protein MxA , GTP-binding protein , interferon-inducible myxovirus resistance-1 protein , interferon-inducible protein p78 , myxovirus (influenza) resistance 1, (murine homolog) , GTP-binding protein Mx1 , oligodendrocyte GTP-binding protein , oligodendrocyte nucleotide-binding protein

GENE ID SPECIES
24575 Rattus norvegicus
17857 Mus musculus
4599 Homo sapiens
397128 Sus scrofa
280872 Bos taurus
403745 Canis lupus familiaris
715186 Macaca mulatta
443146 Ovis aries
100034192 Equus caballus
100174697 Pongo abelii
Selected quality suppliers for MX1 Proteins (MX1)
Did you look for something else?