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NAGK encodes a member of the N-acetylhexosamine kinase family. Additionally we are shipping NAGK Antibodies (81) and NAGK Kits (5) and many more products for this protein.
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Human NAGK Protein expressed in Escherichia coli (E. coli) - ABIN1098243
Weihofen, Berger, Chen, Saenger, Hinderlich: Structures of human N-Acetylglucosamine kinase in two complexes with N-Acetylglucosamine and with ADP/glucose: insights into substrate specificity and regulation. in Journal of molecular biology 2006
Show all 2 references for ABIN1098243
Data shows associations between NAGK, speckle, paraspeckle and general transcription factor suggesting its regulatory roles in gene expression.
Participants with homozygous mutations in the N-acetylmannosamine kinase (GNK) domain have an earlier disease onset than heterozygous participants with mutations in the uridine diphosphate-N-acetylglucosamine 2-epimerase (GNE (show GNE Proteins)) and GNK domains.
The cell-free system was validated for MNK activity, and it revealed that mutations in one enzymatic domain (in MNK, A631V, M712T) affected not only that domain's enzyme activity, but also the activity of the other domain.
Phosphorylation of Tyr205 may modulate GlcNAc kinase activity and/or specificity.
This gene encodes a member of the N-acetylhexosamine kinase family. The encoded protein catalyzes the conversion of N-acetyl-D-glucosamine to N-acetyl-D-glucosamine 6-phosphate, and is the major mammalian enzyme which recovers amino sugars.
, n-acetylglucosamine kinase
, N-acetyl-D-glucosamine kinase
, glcNAc kinase
, GlcNAc kinase