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anti-N-Acetylglutamate Synthase (NAGS) Antibodies

The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. Additionally we are shipping NAGS Proteins (25) and NAGS Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NAGS 162417 Q8N159
NAGS 217214 Q8R4H7
NAGS 303563  
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Top anti-NAGS Antibodies at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-NAGS Antibody Titration: 1.25ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Dog Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated WB NAGS antibody used at 1.25 ug/ml to detect target protein. 100 μg Log in to see 3 to 4 Days
$388.93
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 14 Days
$527.15
Details
Human Mouse Un-conjugated ELISA, WB NAGS polyclonal antibody (A01), Lot # 060106JC01 Western Blot analysis of NAGS expression in K-562 . Western Blot detection against Immunogen (36.89 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 8 to 10 Days
$463.83
Details
Human Rabbit Un-conjugated IF, ELISA, WB   50 μL Log in to see 9 to 11 Days
$313.50
Details
Human Rabbit Un-conjugated IF, IHC, WB   100 μL Log in to see 11 to 16 Days
$675.71
Details
Human Rabbit Un-conjugated IF, ELISA, WB   50 μL Log in to see 3 to 4 Days
$510.36
Details

NAGS Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human
,

Mouse (Murine)


Rat (Rattus)


Top referenced anti-NAGS Antibodies

  1. Cow (Bovine) Polyclonal NAGS Primary Antibody for WB - ABIN2784450 : Schmidt, Nuoffer, Häberle, Pauli, Guffon, Vianey-Saban, Wermuth, Koch: Identification of novel mutations of the human N-acetylglutamate synthase gene and their functional investigation by expression studies. in Biochimica et biophysica acta 2005 (PubMed)

More Antibodies against NAGS Interaction Partners

Human N-Acetylglutamate Synthase (NAGS) interaction partners

  1. Data indicate the formation of alternative N-acylglutamates by N-acetylglutamate synthase (NAGS).

  2. Sp1 (show PSG1 Antibodies), CREB (show CREB1 Antibodies), HNF-1 (show HNF1A Antibodies), and NF-Y, known to be responsive to hormones and diet, regulate NAGS transcription

  3. NAGS deficiency in humans leads to hyperammonemia and can be primary, due to mutations in the NAGS gene or secondary due to other mitochondrial aberrations that interfere with the normal function of the same enzyme.

  4. After the human NAGS gene was identified, mutation analysis revealed that the older sibling on NCG therapy was homozygous for a 971G>A (W324X) mutation.

  5. The first mutation in NAGS has been reported in a family with carbamylglutamate responsive hyperammonemia and normal activity of the urea cycle enzymes.

  6. Gene product expressed in E. coli shown to have NAGS enzyme activity. Gene name provisionally was assigned as NAT7.

  7. report two deleterious mutations within the NAGS gene found in two families with infants presenting with acute neonatal disease; finding confirms the genetic origin of NAGS deficiency

  8. first report of mutation analysis in a series of families affected with deficiency of NAGS

  9. 3 mutations in 2 families with NAGS deficiency revealed deleterious effects on NAGS affinity for substrates & the rate of catalysis.

  10. Three novel mutations in the NAGS gene from the families affected by autosomal recessively inherited NAGS deficiency were described and characterized.

Pig (Porcine) N-Acetylglutamate Synthase (NAGS) interaction partners

  1. The intestinal NAGS mRNA levels were lower in 7- to 28-day-old than in 1-day-old pigs. Immunochemical analysis revealed that NAGS protein was localized in enterocytes of the gut (show GUSB Antibodies).

Mouse (Murine) N-Acetylglutamate Synthase (NAGS) interaction partners

  1. Sp1 (show SP1 Antibodies), CREB (show CREB1 Antibodies), HNF-1 (show HNF1A Antibodies), and NF-Y, known to be responsive to hormones and diet, regulate NAGS transcription

  2. Is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG (show SCN7A Antibodies))

  3. The biochemical properties of purified recombinant human and mouse NAGS-M and NAGS-C were determined in this study with the goal of better understanding the role of the variable domain in NAGS function.

NAGS Antigen Profile

Protein Summary

The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.

Gene names and symbols associated with NAGS

  • N-acetylglutamate synthase (argA) antibody
  • N-acetylglutamate synthase (ECs3675) antibody
  • N-acetylglutamate synthase (VP2371) antibody
  • N-acetylglutamate synthase (Psyr_0254) antibody
  • N-acetylglutamate synthase (Sde_0360) antibody
  • N-acetylglutamate synthase (NAGS) antibody
  • N-acetylglutamate synthase (Nags) antibody
  • 1700120E20Rik antibody
  • AGAS antibody
  • argA antibody
  • RGD1565783 antibody
  • VF0585 antibody

Protein level used designations for NAGS

N-acetylglutamate synthase , N-acetylglutamate synthase, mitochondrial , amino-acid acetyltransferase , amino-acid N-acetyltransferase

GENE ID SPECIES
879475 Pseudomonas aeruginosa PAO1
916513 Escherichia coli O157:H7 str. Sakai
957960 Escherichia coli O157:H7 str. EDL933
1109804 Buchnera aphidicola str. APS (Acyrthosiphon pisum)
1171849 Shewanella oneidensis MR-1
1178706 Vibrio vulnificus CMCP6
1189884 Vibrio parahaemolyticus RIMD 2210633
2765021 Yersinia pestis biovar Microtus str. 91001
2955212 Yersinia pseudotuberculosis IP 32953
3090331 Burkholderia mallei ATCC 23344
3181020 Aromatoleum aromaticum EbN1
3277126 Vibrio fischeri ES114
3365730 Pseudomonas syringae pv. syringae B728a
3480313 Pseudomonas protegens Pf-5
3964826 Saccharophagus degradans 2-40
4713614 Yersinia enterocolitica subsp. enterocolitica 8081
8165153 Photorhabdus asymbiotica subsp. asymbiotica ATCC 43949
162417 Homo sapiens
490943 Canis lupus familiaris
100048960 Sus scrofa
538004 Bos taurus
217214 Mus musculus
303563 Rattus norvegicus
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