You are viewing an incomplete version of our website. Please click to reload the website as full version.

N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) ELISA Kits

ASAH1 encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. Additionally we are shipping N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Antibodies (67) and N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ASAH1 427 Q13510
Anti-Rat ASAH1 ASAH1 84431 Q6P7S1
ASAH1 11886 Q9WV54
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 ELISA Kits at antibodies-online.com

Showing 3 out of 5 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.61 ng/mL 1.56-100 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details
Chicken
  96 Tests Log in to see 16 to 21 Days
$999.43
Details
Mouse
  96 Tests Log in to see 16 to 21 Days
$999.43
Details

More ELISA Kits for N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Interaction Partners

Human N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) interaction partners

  1. Data suggest up-regulation of ASAH1 activity by androgen in androgen-sensitive prostate cancer cells (not other cancer cells) is due to prolonged stability of ASAH1 by androgen-stimulated induction of USP2 (ubiquitin specific peptidase 2 (show USP2 ELISA Kits)) expression.

  2. Genetic or pharmacological acid ceramidase inhibition promotes cisplatin cytotoxicity in head and neck tumor cells.

  3. high ASAH1 expression is generally associated with an improved prognosis in invasive breast cancer independent of adjuvant treatment and could also be valuable as prognostic factor for pre-invasive DCIS.

  4. novel ASAH1 mutations affecting polypyrimidine tract deletion, and exon skipping and resulting in Farber lipogranulomatosis

  5. Acid ceramidase promotes nuclear export of PTEN through sphingosine 1-phosphate mediated Akt (show AKT1 ELISA Kits) signaling.

  6. Depletion of both Akt2 (show AKT2 ELISA Kits) and ASAH1 is much more potent than depleting each alone at inhibiting neoplastic cell viability/proliferation and invasion.

  7. This work unravels for the first time the mutations underlying the neonatal form of Farber disease and represents the first report of a large deletion identified in the ASAH1 gene.

  8. Immunohistochemical analysis of human prostate cancer tissues revealed higher levels of ASAH1 after radiotherapy failure.

  9. These observations confirm ASAH1 as a therapeutic target in advanced and chemoresistant forms of prostate cancer

  10. Acid ceramidase is a prognostic factor in epithelial ovarian cancer

Mouse (Murine) N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) interaction partners

  1. cells deficient in acid ceramidase (aCDase) also exhibited defects in CCL5 (show CCL5 ELISA Kits) induction, whereas cells deficient in sphingosine kinase-1 (show SPHK1 ELISA Kits) and -2 exhibited higher levels of CCL5 (show CCL5 ELISA Kits).

  2. biochemistry of acid ceramidase reaction with acid sphingomyelinase (show SMPD1 ELISA Kits)

  3. Acid and neutral sphingomyelinase (show SMPD2 ELISA Kits), ceramide synthase, and acid ceramidase have roles in cutaneous aging

  4. These results provide the first characterization of the Acid Ceremidase promoter from any species and demonstrate that Kruppel-like factor 6 (KLF6 (show KLF6 ELISA Kits)) is one transcription factor involved in the regulation of AC gene expression.

  5. acid ceramidase is an essential factor required for embryo survival that functions by removing ceramide from the newly formed embryos, thus inhibiting the default apoptosis pathway

N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) Antigen Profile

Antigen Summary

This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene.

Gene names and symbols associated with ASAH1

  • N-acylsphingosine amidohydrolase (acid ceramidase) 1 (asah1) antibody
  • N-acylsphingosine amidohydrolase (acid ceramidase) 1a (asah1a) antibody
  • N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ASAH1) antibody
  • N-acylsphingosine amidohydrolase (acid ceramidase) 1 (Asah1) antibody
  • N-acylsphingosine amidohydrolase 1 (Asah1) antibody
  • Protein ASAH-1 (asah-1) antibody
  • 2310081N20Rik antibody
  • AC antibody
  • ACDase antibody
  • Asah antibody
  • ASAH1 antibody
  • MGC82286 antibody
  • PHP antibody
  • PHP32 antibody
  • SMAPME antibody
  • zgc:101637 antibody

Protein level used designations for ASAH1

N-acylsphingosine amidohydrolase (acid ceramidase) 1 , N-acylsphingosine amidohydrolase 1 , acid ceramidase , acid CDase , acylsphingosine deacylase , putative 32 kDa heart protein , AC , ACDase , Acylsphingosine deacylase

GENE ID SPECIES
447327 Xenopus laevis
450068 Danio rerio
703699 Macaca mulatta
100171626 Pongo abelii
427 Homo sapiens
482897 Canis lupus familiaris
510620 Bos taurus
84431 Rattus norvegicus
464022 Pan troglodytes
422727 Gallus gallus
11886 Mus musculus
173120 Caenorhabditis elegans
Selected quality suppliers for N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) ELISA Kits
Did you look for something else?