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N-Ethylmaleimide-Sensitive Factor Proteins (NSF)

Required for vesicle-mediated transport. Additionally we are shipping NSF Antibodies (90) and NSF Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NSF 18195 P46460
NSF 60355 Q9QUL6
NSF 4905 P46459
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Top NSF Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Rat His tag 50 μg Log in to see 21 to 26 Days
$313.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$4,176.33
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   50 μg Log in to see 3 to 4 Days
$310.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

NSF Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus) ,

Human , ,
,

More Proteins for N-Ethylmaleimide-Sensitive Factor (NSF) Interaction Partners

Xenopus laevis N-Ethylmaleimide-Sensitive Factor (NSF) interaction partners

  1. NSF- and SNARE (show NAPA Proteins)-mediated membrane fusion events are essential steps during Nuclear envelope formation downstream of Nup107 (show NUP107 Proteins) recruitment, and upstream of membrane flattening and completion of nuclear pore complex assembly.

Mouse (Murine) N-Ethylmaleimide-Sensitive Factor (NSF) interaction partners

  1. identify conserved sequences in the 3'UTR of NSF as miR (show MLXIP Proteins)-33 responsive elements and show that Nsf is specifically recruited to the RNA-induced silencing complex following induction of miR (show MLXIP Proteins)-33

  2. Arr1 (show SAG Proteins) and NSF interaction are necessary for both maintenance and modulation of normal photoreceptor synaptic regulation and NSF-RP2 (show RP2 Proteins) interaction may play an important role in membrane protein trafficking in the photoreceptor.

  3. These findings identify new roles for N-ethylmaleimide-sensitive factor and protein kinase C epsilon (show PRKCE Proteins) in regulating synaptic inhibition through downregulation of GABA(A) receptors

  4. interaction of AMPA (show GRIA3 Proteins) receptors with N-ethylmaleimide-sensitive factor plays a critical role in incorporation of AMPA (show GRIA3 Proteins) receptors into synapses and for their subsequent removal during cerebellar long term depression

  5. PICK1 (show PICK1 Proteins) and NSF dynamically regulate the synaptic delivery of GluR2 (show GRIA2 Proteins)-containing receptors during CARP (show ANKRD1 Proteins) and thus regulate the calcium permeability of AMPA (show GRIA3 Proteins) receptors at excitatory synapses.

  6. H(2)O(2) regulates exocytosis by inhibiting N-ethylmaleimide sensitive factor (NSF), a protein that regulates membrane fusion events necessary for exocytosis.

  7. important role for NSF activity in regulating the cell surface stability of GABA(A) receptors.

  8. dual regulation on hbeta2AR trafficking and signaling by NSF through direct binding to cargo receptor and its ATPase activity.

  9. These results indicate that phosphorylation of GluR2 (show GRIA2 Proteins) S880 and NSF and PICK1 (show PICK1 Proteins) binding to GluR2 (show GRIA2 Proteins) dynamically regulate GluR2 (show GRIA2 Proteins) recycling.

  10. Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide sensitive factor

Human N-Ethylmaleimide-Sensitive Factor (NSF) interaction partners

  1. a processive helicase-like mechanism for NSF in which approximately 1 residue is unwound for every hydrolyzed ATP molecule.

  2. Single and multiple-marker analyses revealed a strong association between cocaine dependence and the NSF gene.

  3. Knockdown of TRX1 (show MLL Proteins) increases the level of S-nitrosylated NSF, prolongs the inhibition of exocytosis, and suppresses leukocyte

  4. NSF independent fusion of Salmonella-containing late phagosomes with early endosomes.

  5. analysis of human NSF possible binding mode to GABARAP (show GABARAP Proteins) and GATE-16 (show GABARAPL2 Proteins)

  6. binding of NSF to GluR2 (show GRIA2 Proteins)-containing AMPARs in stabilizing these receptors in the synaptic membrane and impeding their regulated endocytosis.

  7. role of interaction with GluR2 (show GRIA2 Proteins) in regulation of AMPA (show GRIA3 Proteins) receptors by brain-derived neurotrophic factor (show BDNF Proteins)

  8. Nitric oxide regulates exocytosis by S-nitrosylation of NSF.

  9. Expressing a biochemically defined NSF mutant that lacks ATPase activity results in a dramatic inhibition of stimulated mast cell exocytosis.

  10. NSF dissociates the VAMP-2 (show VAMP2 Proteins).SNAP-25 (show SNAP25 Proteins).syntaxin 13 (show STX12 Proteins) complex, but has no effect on the Hrs-containing complex.

Cow (Bovine) N-Ethylmaleimide-Sensitive Factor (NSF) interaction partners

  1. Report depletion of the ATPase NSF from Golgi membranes with hypo-S-nitrosylation of vasorelevant proteins in endothelial cells exposed to monocrotaline pyrrole.

Zebrafish N-Ethylmaleimide-Sensitive Factor (NSF) interaction partners

  1. results establish a role for Nsf in the maintenance of synaptic contacts between hair cells and afferent neurons, mediated in part via the secretion of trophic signaling factors

  2. Nsf is essential in the formation of the nodes of Ranvier in the vertebrate nervous system.

  3. Activation of PKCgamma (show PRKCG Proteins) is necessary for the activity-dependent trafficking of AMPARs in embryonic zebrafish and is NMDA and SNARE (show NAPA Proteins)-dependent and requires AMPARs to associate with both NSF and PICK1 (show PICK1 Proteins).

  4. This study analyses of nsf mutant zebrafish reveal an unexpected role for NSF in hypothalamic development, with mutant 5 days post-fertilization larvae exhibiting a stage-dependent loss of neuroendocrine transcripts.

NSF Protein Profile

Protein Summary

Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling (By similarity).

Gene names and symbols associated with NSF

  • N-ethylmaleimide-sensitive factor (NSF)
  • N-ethylmaleimide-sensitive factor (nsf)
  • N-ethylmaleimide-sensitive factor (BBOV_II007200)
  • N-ethylmaleimide-sensitive factor (TGME49_118510)
  • N-ethylmaleimide sensitive factor (NSF)
  • N-ethylmaleimide sensitive factor (nsf)
  • N-ethylmaleimide sensitive fusion protein (Nsf)
  • N-ethylmaleimide-sensitive factor (Nsf)
  • N-ethylmaleimide-sensitive factor a (nsfa)
  • 18.m06598 protein
  • AI316878 protein
  • AU020090 protein
  • AU067812 protein
  • N-ethylmaleimide sensitive factor protein
  • nsf protein
  • si:bz18k17.1 protein
  • SKD2 protein
  • T1J1.4 protein
  • T1J1_4 protein
  • wu:fj33g11 protein

Protein level used designations for NSF

vesicle-fusing ATPase , N-ethylmaleimide-sensitive factor , N-ethylmaleimide-sensitive fusion protein , NEM-sensitive fusion protein , vesicular-fusion protein NSF , vesicle-fusing ATPase-like , N-ethylmaleimide sensitive factor , suppressor of K(+) transport growth defect 2 , N-ethylmaleimide sensitive fusion protein , N-ethylmaleimide-sensitive factor-like protein

GENE ID SPECIES
373397 Strongylocentrotus purpuratus
454819 Pan troglodytes
780249 Xenopus (Silurana) tropicalis
5478472 Babesia bovis T2Bo
7901210 Toxoplasma gondii ME49
100024726 Monodelphis domestica
100049722 Xenopus laevis
100063690 Equus caballus
100174078 Pongo abelii
100180685 Ciona intestinalis
100472215 Ailuropoda melanoleuca
100519170 Sus scrofa
9310886 Arabidopsis lyrata subsp. lyrata
779070 Xenopus laevis
825830 Arabidopsis thaliana
18195 Mus musculus
60355 Rattus norvegicus
419972 Gallus gallus
4905 Homo sapiens
504457 Bos taurus
490921 Canis lupus familiaris
100624659 Sus scrofa
101120344 Ovis aries
368483 Danio rerio
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