anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) Antibodies

NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. Additionally we are shipping NQO1 Kits (30) and NQO1 Proteins (16) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NQO1 1728 P15559
NQO1 24314 P05982
NQO1 18104 Q64669
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Top anti-NQO1 Antibodies at antibodies-online.com

Showing 10 out of 224 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN184714 staining (0.03µg/ml) of Human Kidney lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-NQO1 AntibodyTitration: 1.0 µg/mL <br /> Positive Control: 721_B Whole Cell <br /> There is BioGPS gene expression data showing that NQO1 is expressed in 721_B 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-NQO1 AntibodyTitration: 1.0 µg/mL <br /> Positive Control: HT1080 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Anti- NQO1 Picoband antibody, Western blotting All lanes: Anti NQO1  at 0.5ug/ml Lane 1: Rat Liver Tissue Lysate at 50ug Lane 2: Rat Lung Tissue Lysate at 50ug Lane 3: HELA Whole Cell Lysate at 40ug Lane 4: A549 Whole Cell Lysate at 40ug Lane 5: MM231 Whole Cell Lysate at 40ug Lane 6: SW620 Whole Cell Lysate at 40ug Lane 7: 22RV1 Whole Cell Lysate at 40ug Predicted bind size: 31KD Observed bind size: 31KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$275.00
Details
Dog Mouse Un-conjugated FACS, ICC, IF, IHC, IHC (fro), IHC (p), IP, SimWes, WB Detection of NQO1 in A549 lysates using ABIN152344.  Lane 1: 0.5 ug/ml.  Lane 2: 2 ug/ml. Exposure: 1 second. Simple Western: NQO-1 Antibody (A180) [ABIN152344] - Simple Western lane view shows a specific band for NQO-1 in 0.5 mg/ml of A431 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. 0.1 mL Log in to see 7 to 9 Days
$447.56
Details
Dog Goat Un-conjugated ELISA, WB ABIN249473 staining (1ug/ml) of Human Lung lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence ABIN249473 staining (0.5µg/ml) of Human Kidney lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse colon carcinoma labeled with Anti-NQO1 Polyclonal Antibody, Unconjugated (ABIN678428) at 1:200, followed by conjugation to the secondary antibody and DAB staining L1 rat liver lysates L2 rat brain lysates probed with Anti NQO1 Polyclonal Antibody, Unconjugated (ABIN678428) at 1:200 overnight at 4 °C. Followed by conjugation to secondary antibody at 1:3000 for 90 min at 37 °C. Predicted band 30kD. Observed band size:30kD. 100 μL Log in to see 3 to 7 Days
$307.45
Details
Mouse Mouse Un-conjugated ICC, FACS, IF, IHC (p), IP, ELISA, WB 50 μL Log in to see 7 to 8 Days
$402.29
Details
Human Mouse Un-conjugated FACS, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of NIH/3T3 cells using NQO1 mouse mAb (green) and negative control (red) . 100 μL Log in to see 2 to 3 Days
$430.10
Details

NQO1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-NQO1 Antibodies

  1. Dog (Canine) Monoclonal NQO1 Primary Antibody for FACS, ICC - ABIN152344 : Siegel, Franklin, Ross: Immunohistochemical detection of NAD(P)H:quinone oxidoreductase in human lung and lung tumors. in Clinical cancer research : an official journal of the American Association for Cancer Research 1998 (PubMed)
    Show all 25 Pubmed References

  2. Human Polyclonal NQO1 Primary Antibody for ICC, IF - ABIN4340592 : Heitz, Erb, Anklin, Robay, Pernet, Gueven: Idebenone protects against retinal damage and loss of vision in a mouse model of Leber's hereditary optic neuropathy. in PLoS ONE 2012 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal NQO1 Primary Antibody for IF (p), IHC (p) - ABIN678428 : Wang, Peng, Wei, Wei, Wang, Ma, Yao, Fu, Zu: Geraniin exerts cytoprotective effect against cellular oxidative stress by upregulation of Nrf2-mediated antioxidant enzyme expression via PI3K/AKT and ERK1/2 pathway. in Biochimica et biophysica acta 2015 (PubMed)
    Show all 3 Pubmed References

  4. Dog (Canine) Polyclonal NQO1 Primary Antibody for ELISA, WB - ABIN249473 : Singh, Zahid, Saeed, Gaikwad, Meza, Cavalieri, Rogan, Chakravarti: NAD(P)H:quinone oxidoreductase 1 Arg139Trp and Pro187Ser polymorphisms imbalance estrogen metabolism towards DNA adduct formation in human mammary epithelial cells. in The Journal of steroid biochemistry and molecular biology 2009 (PubMed)
    Show all 3 Pubmed References

  5. Human Monoclonal NQO1 Primary Antibody for IHC (p), IP - ABIN2475931 : Honda: [Status of emergencies and their transport system in Tokyo]. in [Kango gijutsu] : [Nursing technique] 1975 (PubMed)
    Show all 4 Pubmed References

  6. Human Monoclonal NQO1 Primary Antibody for IHC (p), WB - ABIN2475932 : Anwar, Siegel, Kepa, Ross: Interaction of the molecular chaperone Hsp70 with human NAD(P)H:quinone oxidoreductase 1. in The Journal of biological chemistry 2002 (PubMed)
    Show all 4 Pubmed References

  7. Human Monoclonal NQO1 Primary Antibody for FACS, IHC - ABIN969319 : Kansanen, Jyrkkänen, Volger, Leinonen, Kivelä, Häkkinen, Woodcock, Schopfer, Horrevoets, Ylä-Herttuala, Freeman, Levonen: Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: identification of heat shock response as the major pathway activated by nitro-oleic acid. in The Journal of biological chemistry 2009 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal NQO1 Primary Antibody for FACS, ELISA - ABIN969320 : Douglas, Lim, Porter, West, Pink, Ge, Wylie, Tibbits, Biggs, Curtis, Palombella, Adams, Fritz, Normant: The antiproliferative activity of the heat shock protein 90 inhibitor IPI-504 is not dependent on NAD(P)H:quinone oxidoreductase 1 activity in vivo. in Molecular cancer therapeutics 2009 (PubMed)
    Show all 2 Pubmed References

  9. Human Polyclonal NQO1 Primary Antibody for WB - ABIN1686087 : La Sala, Pujadas, De Nigris, Canivell, Novials, Genovese, Ceriello: Oscillating glucose and constant high glucose induce endoglin expression in endothelial cells: the role of oxidative stress. in Acta diabetologica 2014 (PubMed)

  10. Mouse (Murine) Monoclonal NQO1 Primary Antibody for ICC, FACS - ABIN1042634 : Siegel, Ross: Immunodetection of NAD(P)H:quinone oxidoreductase 1 (NQO1) in human tissues. in Free radical biology & medicine 2001 (PubMed)

More Antibodies against NQO1 Interaction Partners

Zebrafish NAD(P)H Dehydrogenase, Quinone 1 (NQO1) interaction partners

  1. Coptisine exerted its antioxidant activity against AAPH-induced toxicity involving in activating Akt (show AKT1 Antibodies) and JNK (show MAPK8 Antibodies)/Nrf2 (show NFE2L2 Antibodies)/NQO1 pathway.

Human NAD(P)H Dehydrogenase, Quinone 1 (NQO1) interaction partners

  1. Results show that H80R causes a population shift in the conformational ensemble of apo (show C9orf3 Antibodies)-P187S, remodelling the structure and dynamics of the FAD (show BRCA2 Antibodies)-binding site and reducing the energetic penalization arising from the equilibrium between apo (show C9orf3 Antibodies)- and holo-states.

  2. The C609T polymorphism within NQO1 is independently associated with CAD (show CAD Antibodies) in women, but no association was observed in whole study population or in men.

  3. This study suggests that HNC (show MMP8 Antibodies) samples should be screened for NQO1 expression to identify patients that will likely benefit from combined therapy with beta-lap and IR.

  4. The results indicate that NQO1*2 genotype may increase susceptibility to DN in north Indian subjects with T2DM.

  5. Thus, our findings indicated that NQO1 could stabilize Herp (show HERPUD1 Antibodies) protein expression via indirect regulation of synoviolin.

  6. NQO1 and GCLC (show GCLC Antibodies) were both functionally sufficient to autonomously confer a tamoxifen-resistant metabolic phenotype, characterized by i) increased mitochondrial biogenesis, ii) increased ATP production and iii) reduced glutathione levels.

  7. NQO1 induces hepatocellular carcinoma cell apoptosis and proliferation inhibition through the AMPK (show PRKAA1 Antibodies)/PGC-1alpha (show PPARGC1A Antibodies) pathway.

  8. the expression of NRF2 (show GABPA Antibodies), KEAP1 (show KEAP1 Antibodies), NQO-1 and HO-1 (show HMOX1 Antibodies) are increased significantly in advanced laryngeal squamous cell carcinoma, compared with the adjacent normal mucosa. Remarkable relevance exists between high expression of KEAP1 (show KEAP1 Antibodies), NQO-1, HO-1 (show HMOX1 Antibodies) and nuclear NRF2 (show GABPA Antibodies). their expression levels were independent of age, tumor stage (clinical stage III and IV), tumor size and lymph node metastasis.

  9. (i) melatonin counteracted UVR-induced alterations in the ATP synthesis and reduced free radical formation; (ii) melatonin induced the translocation of Nrf2 (show GABPA Antibodies) transcription factor from the cytosol into the nucleus resulting in, (iii) melatonin enhanced gene expression of phase-2 antioxidative enzymes including gamma-glutamylcysteine synthetase (show GCLC Antibodies) (gamma-GCS (show GCLC Antibodies)), heme oxygenase-1 (HO-1 (show HMOX1 Antibodies)), and NADPH: quinone dehydrogenase-1 (NQO1...

  10. Coptisine exerted its antioxidant activity against AAPH-induced toxicity involving in activating Akt (show AKT1 Antibodies) and JNK (show MAPK8 Antibodies)/Nrf2 (show GABPA Antibodies)/NQO1 pathway.

Mouse (Murine) NAD(P)H Dehydrogenase, Quinone 1 (NQO1) interaction partners

  1. NQO1 and autophagy participate in a protective role in cisplatin injury.

  2. A significant increase was found in Nrf2 (show NFE2L2 Antibodies)-ARE activity after partial hepatectomy (PHx). The signal maximum was recorded on the third day after PHx. Significantly more hepatocytes were positive for Nrf2 (show NFE2L2 Antibodies) and HO-1 (show HMOX1 Antibodies) on the third postoperative day compared with baseline levels. The mRNA expression of HO-1 (show HMOX1 Antibodies) and NQO1 were significantly increased on day 3.

  3. Miroestrol restored hepatic NQO1 expression in beta-naphthoflavone-treated mice.

  4. previous and present results collectively show that NQO1 is involved in the formation of tight junctions in the small intestine, and that defects in NQO1 enhance C. difficile toxin A-induced acute inflammatory responses, presumably via the loss of epithelial cell tight junctions

  5. NQO1 plays a critical role in protection against energy depletion in acetaminophen-induced liver injury, and is associated with improvement of mitochondrial dysfunction

  6. The present results demonstrate that exacerbated cisplatin-induced nephrotoxicity under the NQO1-knockout condition was accompanied by the reduced expression of MRN complex proteins, ATM (show ATM Antibodies), PARP1 (show PARP1 Antibodies), and Sirt1 (show SIRT1 Antibodies).

  7. Taken together, these data suggest that EEEC attenuates oxidative stress by activating Nrf2 (show NFE2L2 Antibodies)-mediated HO-1 (show HMOX1 Antibodies) and inducing NQO-1 via the activation of MAPK (show MAPK1 Antibodies) signaling pathways.

  8. We defined the basal and butylated hydroxyanisole induced expression patterns of Nqo1, AKR1B8, and Ho-1 (show HMOX1 Antibodies) in the liver and small intestine of C57BL/6 mice.

  9. The colons of NQO1-KO mice also showed high levels of reactive oxygen species (ROS (show ROS1 Antibodies)) and histone deacetylase (HDAC (show HDAC1 Antibodies)) activity, which are known to affect transcriptional regulation.

  10. the induction of cellular NAD(+) levels using beta-lapachone (beta-Lap), whose intracellular target is NQO1, prevents the toxic effects of cisplatin through the regulation of PARP-1 (show PARP1 Antibodies) and SIRT1 (show SIRT1 Antibodies) activity.

Pig (Porcine) NAD(P)H Dehydrogenase, Quinone 1 (NQO1) interaction partners

  1. The obtained data convincingly showed that porcine NADPH-d cells may produce nitric oxide.

  2. Immunoreactivity of eNOS (show NOS3 Antibodies) was similar to NADPH-d staining. Clear iNOS (show NOS2 Antibodies) immunoreactivity was detected in the luminal epithelium, endometrial stroma and individual endometrial glands.

Cow (Bovine) NAD(P)H Dehydrogenase, Quinone 1 (NQO1) interaction partners

  1. NQO1 expression was increased in the ruminal papillae of more efficient low residual feed intake (RFI (show RNF34 Antibodies)) animals compared to the high RFI (show RNF34 Antibodies) animals

NQO1 Antigen Profile

Protein Summary

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with NQO1

  • NAD(P)H dehydrogenase, quinone 1 (nqo1) antibody
  • NAD(P)H dehydrogenase, quinone 1 (NQO1) antibody
  • NAD(P)H dehydrogenase, quinone 1 (Bpet2092) antibody
  • NAD(P)H dehydrogenase, quinone 1 (Nqo1) antibody
  • AV001255 antibody
  • DHQU antibody
  • Dia4 antibody
  • Dtd antibody
  • NADPH-d antibody
  • Nmo-1 antibody
  • Nmo1 antibody
  • Nmor1 antibody
  • NMORI antibody
  • nqo1 antibody
  • Ox-1 antibody
  • Ox1 antibody
  • Qr1 antibody
  • wu:fb63c10 antibody
  • zgc:77191 antibody

Protein level used designations for NQO1

NAD(P)H dehydrogenase [quinone] 1 , NAD(P)H menadione oxidoreductase 1, dioxin-inducible , NAD(P)H dehydrogenase, quinone 1 , DT-diaphorase , DTD , NAD(P)H:quinone oxidoreductase 1 , QR1 , azoreductase , menadione reductase , phylloquinone reductase , quinone reductase 1 , nad(p)h dehydrogenase (quinone) 1 , NAD(P)H:Quinone acceptor oxidoreductase type 1 , NAD(P)H:menadione oxidoreductase 1 , NAD(P)H:quinone oxireductase , diaphorase (NADH/NADPH) (cytochrome b-5 reductase) , diaphorase-4 , dioxin-inducible 1 , Diaphorase (NADH/NADPH) , NAD(P)H:menadione oxidoreductase , NAD(P)H dehydrogenase (quinone) , NAD(P)H menadione oxidoreductase 1, dioxin inducible , diaphorase 4 (NADH/NADPH) , nicotinamide adenine dinucleotide phosphate diaphorase , diaphorase 4 , NAD(P)H: quinone oxidoreductase 1

GENE ID SPECIES
322506 Danio rerio
468012 Pan troglodytes
549222 Xenopus (Silurana) tropicalis
705635 Macaca mulatta
769737 Gallus gallus
4606922 Azoarcus sp. BH72
5818094 Bordetella petrii DSM 12804
100049751 Xenopus laevis
100172039 Pongo abelii
100528193 Ictalurus punctatus
1728 Homo sapiens
610935 Canis lupus familiaris
24314 Rattus norvegicus
18104 Mus musculus
100286873 Sus scrofa
519632 Bos taurus
100135582 Cavia porcellus
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