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anti-NAD Dependent Malate Dehydrogenase (NAD-ME) Antibodies

NAD-ME encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. Additionally we are shipping NAD Dependent Malate Dehydrogenase Proteins (4) and NAD Dependent Malate Dehydrogenase Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NAD-ME 4200 P23368
NAD-ME 307270  
NAD-ME 107029 Q99KE1
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Top anti-NAD Dependent Malate Dehydrogenase Antibodies at antibodies-online.com

Showing 10 out of 30 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ME2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Jurkat cell lysate Host: Rabbit  Target Name: ME2  Sample Tissue: Human Fetal Heart  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from RAW264.7/LOVO cells, using ME2 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using ME2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue reacted with NAD-ME Antibody (C-term) followed which was peroxidase conjugated to the secondary antibody and followed by DAB staining. Western blot analysis of NAD-ME Antibody (C-term) in mouse NIH-3T3,Neuro-2a cell line lysates (35ug/lane). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB ME2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ME2 Antibody (C-term) for immunohistochemistry.  Clinical relevance has not been evaluated. ME2 Antibody (C-term)  western blot analysis in mouse NIH-3T3,Neuro-2a cell line lysates (35ug/lane).This demonstrates the ME2 antibody detected the ME2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Biotin IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA, IHC, WB   100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated WB ME2 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details

NAD-ME Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


, , , , ,
Rat (Rattus)


Mouse (Murine)


Top referenced anti-NAD Dependent Malate Dehydrogenase Antibodies

  1. Human Polyclonal NAD-ME Primary Antibody for EIA, IHC (p) - ABIN953596 : MacDonald, Longacre, Kendrick: Mitochondrial malic enzyme (ME2) in pancreatic islets of the human, rat and mouse and clonal insulinoma cells. in Archives of biochemistry and biophysics 2009 (PubMed)
    Show all 4 references for ABIN953596

  2. Cow (Bovine) Polyclonal NAD-ME Primary Antibody for WB - ABIN2784265 : Escamilla: Variation in the malic enzyme 2 gene: implications for the pharmacogenomics of psychotic disorders. in Pharmacogenomics 2007 (PubMed)

  3. Human Polyclonal NAD-ME Primary Antibody for IHC, ELISA - ABIN1535055 : Yanaihara, Kohno, Takakura, Takei, Otsuka, Sunaga, Takahashi, Yamazaki, Tashiro, Fukuzumi, Fujimori, Hagiwara, Tanaka, Yokota: Physical and transcriptional map of a 311-kb segment of chromosome 18q21, a candidate lung tumor suppressor locus. in Genomics 2001 (PubMed)

More Antibodies against NAD Dependent Malate Dehydrogenase Interaction Partners

Human NAD Dependent Malate Dehydrogenase (NAD-ME) interaction partners

  1. Data indicate that malic enzyme 2 knockdown impacts phosphatidylinositol 3-kinases/proto-oncogene (show RAB1A Antibodies) protein akt (show AKT1 Antibodies) (PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies)) signaling.

  2. ME2 (show CELSR1 Antibodies) might be an important factor in melanoma progression and a novel biomarker of invasion.

  3. Three SNP alleles in BRD2 (show BRD2 Antibodies), Cx-36 (show GJD2 Antibodies), and ME2 (show CELSR1 Antibodies) and microdeletions in 15q13.3, 15q11.2, and 16p13.11 also contribute risk to juvenile myclonic epilepsy.

  4. p53 (show TP53 Antibodies) represses the expression of the tricarboxylic-acid-cycle-associated malic enzymes ME1 (show ME1 Antibodies) and ME2 (show CELSR1 Antibodies) in human and mouse cells

  5. Depletion of malic enzyme 2 induced erythroid differentiation in human erythroleukemia cells.

  6. An ME2-centered nine-SNP haplotype, when present homozygously, increases the risk for IGE (odds ratio 6.1; 95% confidence interval 2.9-12.7) compared with any other genotype

  7. Schizophrenic subjects are identified with mitochondrial genes involved in oxidative metabolism as showing consistently decreased expression, including ME2 (show CELSR1 Antibodies).

  8. Single nucleotide polymorphism in ME2 (show CELSR1 Antibodies) gene is associated with acute lymphoblastic leukemia.

  9. ME2 (show CELSR1 Antibodies) activity in Islets of Langerhans cells was measured by a spectrophotometric enzyme assay by utilizing the distinct kinetic properties.

Mouse (Murine) NAD Dependent Malate Dehydrogenase (NAD-ME) interaction partners

  1. Conditional expression of E2A (show TCF3 Antibodies)-HLF (show HLF Antibodies) induces B-cell precursor death and myeloproliferative-like disease in knock-in mice.

  2. Upregulation of E12/E47 by HBx ultimately and concomitant repression of E-cadherin (show CDH1 Antibodies) expression led to epithelial-mesenchymal transition in human hepatocytes.

  3. Mechanistically, E47 (show TCF3 Antibodies) repressed the expression of several astrocyte-specific genes in adult NSPCs.

  4. Tcf3 (show TCF7L1 Antibodies) is upregulated in skin wounds and Tcf3 (show TCF7L1 Antibodies) overexpression accelerates keratinocyte migration and skin wound healing.

  5. Loss and gain of function analyses combined with in vivo studies in syngeneic breast cancer models demonstrate the participation of LOXL2 (show LOXL3 Antibodies) and E47 (show TCF3 Antibodies) in tumor growth and their requirement for lung metastasis.

  6. Tcf3 (show TCF7L1 Antibodies) has a role in repressing Wnt (show WNT2 Antibodies)-beta-catenin (show CTNNB1 Antibodies) signaling and maintaining neural stem cell population during neocortical development

  7. the role of Tcf3 (show TCF7L1 Antibodies) in cell-fate decision is more complex than previously appreciated and is highly dependent on cellular context

  8. Id2 represses E2A (show TCF3 Antibodies)-mediated activation of IL-10 (show IL10 Antibodies) expression in T cells.

  9. transcription factor E2A binds to the UNG2 (show UNG Antibodies) promoter and represses UNG2 (show UNG Antibodies) expression.

  10. pre-BCR (show BCR Antibodies) signaling downregulates several components of the recombination machinery, including RAG1 (show RAG1 Antibodies), RAG2 (show RAG2 Antibodies), and PAX5 (show PAX5 Antibodies), through calmodulin (show Calm2 Antibodies) inhibition of E2A (show TCF3 Antibodies).

NAD Dependent Malate Dehydrogenase (NAD-ME) Antigen Profile

Protein Summary

This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.

Gene names and symbols associated with NAD-ME

  • malic enzyme 2, NAD(+)-dependent, mitochondrial (ME2) antibody
  • malic enzyme 2, NAD(+)-dependent, mitochondrial (me2) antibody
  • malic enzyme 2, NAD(+)-dependent, mitochondrial (Me2) antibody
  • transcription factor 3 (Tcf3) antibody
  • A1 antibody
  • AA408400 antibody
  • ALF2 antibody
  • AW120568 antibody
  • AW209082 antibody
  • bHLHb21 antibody
  • D030040L20Rik antibody
  • E2A antibody
  • E12 antibody
  • E12/E47 antibody
  • E47 antibody
  • ME2 antibody
  • NAD-ME antibody
  • ODS1 antibody
  • Pan1 antibody
  • Pan2 antibody
  • Tcfe2a antibody
  • VDIR antibody

Protein level used designations for NAD-ME

NAD-ME , NAD-dependent malic enzyme, mitochondrial , malate dehydrogenase , pyruvic-malic carboxylase , malic enzyme 2 , TCF-3 , immunoglobulin enhancer-binding factor E12/E47 , transcription factor A1 , transcription factor E2-alpha , transcription factor E2a

GENE ID SPECIES
4200 Homo sapiens
398584 Xenopus laevis
476198 Canis lupus familiaris
507817 Bos taurus
307270 Rattus norvegicus
107029 Mus musculus
21423 Mus musculus
Selected quality suppliers for anti-NAD Dependent Malate Dehydrogenase (NAD-ME) Antibodies
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