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NADK catalyzes the transfer of a phosphate group from ATP to NAD to generate NADP, which in its reduced form acts as an electron donor for biosynthetic reactions (Lerner et al., 2001 [PubMed 11594753]).[supplied by OMIM, Mar 2008].. Additionally we are shipping NAD Kinase Antibodies (30) and NAD Kinase Kits (8) and many more products for this protein.
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Depletion of wild-type NADK in pancreatic ductal adenocarcinoma cells attenuates cancer cell growth.
Taken together, this indicates that Ser (show SIGLEC1 Proteins)-188 (and perhaps the other residues) is an important phosphorylation site that can downregulate the NAD kinase activity of this critical enzyme.
Using purified human NAD kinase, we revealed a sigmoidal kinetic behavior toward ATP and the inhibitory effects of NADPH (show NQO1 Proteins) and NADH
NAD kinase levels control the NADPH (show NQO1 Proteins) concentration in human cells
NADK catalyzes the transfer of a phosphate group from ATP to NAD to generate NADP, which in its reduced form acts as an electron donor for biosynthetic reactions (Lerner et al., 2001
Putative inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase)
, poly(P)/ATP NAD kinase