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NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 1, 7.5kDa (NDUFA1) ELISA Kits

The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. Additionally we are shipping NDUFA1 Antibodies (61) and NDUFA1 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse NDUFA1 NDUFA1 54405 O35683
Anti-Rat NDUFA1 NDUFA1 363441  
Anti-Human NDUFA1 NDUFA1 4694 O15239
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More ELISA Kits for NDUFA1 Interaction Partners

Mouse (Murine) NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 1, 7.5kDa (NDUFA1) interaction partners

  1. Species-specific and mutant MWFE proteins effect on the assembly of a functional mammalian mitochondrial complex I.

Human NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 1, 7.5kDa (NDUFA1) interaction partners

  1. Fanconi anemia complementation group A (show FANCA ELISA Kits) mutants show defective respiration through Complex I, diminished ATP production and metabolic sufferance with an increased AMP (show APRT ELISA Kits)/ATP ratio.

  2. Heterozygous mutation in the X chromosomal NDUFA1 gene in a girl with complex I deficiency

  3. Mutations in the NDUFA1 gene is linked to a delayed mitochondrial network recovery in OXPHOS disorders.

  4. Species-specific and mutant MWFE proteins effect on the assembly of a functional mammalian mitochondrial complex I.

  5. A family-based association study finds that the NDUFA1 gene is unlikely to harbor a major visual loss susceptibility locus for Leber hereditary optic neuropathy.

  6. Suppression of NDUFA1 expression could represent a key pathogenic mechanism in the development of basal cell carcinoma

  7. Two novel p.Gly8Arg and p.Arg37Ser hemizygous mutations in NDUFA1 were identified in two unrelated male patients presenting with Leigh's syndrome and with myoclonic epilepsy and developmental delay.

  8. hypothesize that the novel G32R mutation in NDUFA1 is causing complex I deficiency either by itself or in synergy with additional mtDNA variants

Cow (Bovine) NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 1, 7.5kDa (NDUFA1) interaction partners

  1. subunit MWFE is required for assembly into complex I of seven hydrophobic subunits encoded in the mitochondrial genome

NDUFA1 Antigen Profile

Antigen Summary

The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the 'hydrophobic protein' (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function.

Gene names and symbols associated with NDUFA1

  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 (Ndufa1) antibody
  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa (NDUFA1) antibody
  • 1810049F12Rik antibody
  • CI-MWFE antibody
  • MWFE antibody
  • RGD1560955 antibody
  • ZNF183 antibody

Protein level used designations for NDUFA1

CI-MWFE , NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 (7.5kD, MWFE) , NADH dehydrogenase 1 alpha subcomplex, 1 , NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 , NADH ubiquinone oxidoreductase subunit MWFE , NADH-ubiquinone oxidoreductase MWFE subunit , complex I-MWFE , Complex I-MWFE , NADH ubiquinone oxidoreductase NDUFA1 , NADH oxidoreductase subunit MWFE , NADH:ubiquinone oxidoreductase (complex 1) , complex I MWFE subunit , type I dehydrogenase

GENE ID SPECIES
54405 Mus musculus
363441 Rattus norvegicus
100689328 Cricetulus griseus
4694 Homo sapiens
481033 Canis lupus familiaris
327673 Bos taurus
100983914 Pan paniscus
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