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anti-NADH Dehydrogenase (Ubiquinone) Fe-S Protein 2, 49kDa (NADH-Coenzyme Q Reductase) (NDUFS2) Antibodies

The protein encoded by NDUFS2 is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Additionally we are shipping NDUFS2 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NDUFS2 226646 Q91WD5
NDUFS2 289218 Q641Y2
NDUFS2 4720 O75306
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Top anti-NDUFS2 Antibodies at antibodies-online.com

Showing 10 out of 61 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB NDUFS2 Antibody (Center) (ABIN653726) western blot analysis in Y79,A375,Hela cell line and mouse brain,cerebellum tissue lysates (35 µg/lane).This demonstrates the NDUFS2 antibody detected the NDUFS2 protein (arrow). NDUFS2 Antibody (Center) (ABIN653726) IHC analysis in formalin fixed and paraffin embedded hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemistryanalysis in formalin fixed and paraffin embedded hepatocarcinoma reacted with NDUFS2 Antibody (Center) followed which was peroxidase conjugated to the secondary antibody and followed by DAB staining. This data demonstrates the use of the NDUFS2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis of NDUFS2 Antibody (Center) in Y79,A375,Hela cell line and mouse brain,cerebellum tissue lysates (35ug/lane). This demonstrates the NDUFS2 antibody detected the NDUFS2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Goat Un-conjugated EIA, WB Western blot analysis: NDUFS2 antibody staining of Human Heart lysate at 0.1 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Mouse heart lysates probed with Rabbit Anti-NDUFS2 Polyclonal Antibody, Unconjugated (ABIN1714214) at 1:300 overnight at 4˚C. Followed by a conjugated secondary antibody at 1:5000 for 90 min at 37˚C. 100 μL Log in to see 14 to 21 Days
$269.50
Details
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated IHC (p)   100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details

NDUFS2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-NDUFS2 Antibodies

  1. Human Polyclonal NDUFS2 Primary Antibody for IHC (p), WB - ABIN953636 : Saada, Vogel, Hoefs, van den Brand, Wessels, Willems, Venselaar, Shaag, Barghuti, Reish, Shohat, Huynen, Smeitink, van den Heuvel, Nijtmans: Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)-interacting complex I assembly protein, cause fatal neonatal mitochondrial disease. in American journal of human genetics 2009 (PubMed)
    Show all 3 references for ABIN953636

More Antibodies against NDUFS2 Interaction Partners

Mouse (Murine) NADH Dehydrogenase (Ubiquinone) Fe-S Protein 2, 49kDa (NADH-Coenzyme Q Reductase) (NDUFS2) interaction partners

  1. Ndufs2-null mice lose the hyperventilatory response to hypoxia, although they respond to hypercapnia. Ndufs2-deficient CB cells have normal functions and ATP content but are insensitive to changes in PO2.

Human NADH Dehydrogenase (Ubiquinone) Fe-S Protein 2, 49kDa (NADH-Coenzyme Q Reductase) (NDUFS2) interaction partners

  1. Results found nominal significant associations of 2 SNPs in the NDUFS1 (show NDUFS1 Antibodies) gene and 4 SNPs in the NDUFS2 gene with early onset schizophrenia (EOS (show IKZF4 Antibodies)), but none of these associations survived the Bonferroni correction.

  2. NDUFAF7 methylates arginine 85 in the NDUFS2 subunit of human complex I.

  3. study describes clinical, radiological, biochemical and molecular data of 6 patients with Leigh syndrome with novel mutations in NDUFV1 (show NDUFV1 Antibodies) and NDUFS2; 2 siblings were compound heterozygotes for an undescribed E104A mutation in NDUFS2

  4. The NDUFS2 mutation affects complex I enzymatic function.

  5. Our results confirm that NDUFS2 is a mutational hotspot in Caucasian children with isolated complex I deficiency and recommend the routine diagnostic investigation of this gene in patients with Leigh or Leigh-like phenotypes.

Cow (Bovine) NADH Dehydrogenase (Ubiquinone) Fe-S Protein 2, 49kDa (NADH-Coenzyme Q Reductase) (NDUFS2) interaction partners

  1. Data suggest that the active site domain of NDUFS2 (a 49 kDa subunit of mitochondrial complex I) in bovine heart mitochondria exhibits more than one access path by which ligands/chemicals can reach reactive residues.

NDUFS2 Antigen Profile

Protein Summary

The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with NDUFS2

  • NADH dehydrogenase (ubiquinone) Fe-S protein 2 (Ndufs2) antibody
  • NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) (NDUFS2) antibody
  • AL033311 antibody
  • CI-49 antibody

Protein level used designations for NDUFS2

CI-49kD , NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial , NADH-coenzyme Q reductase , NADH-ubiquinone oxidoreductase 49 kDa subunit , complex I-49kD , NADH-ubiquinone oxidoreductase NDUFS2 subunit , complex 1, mitochondrial respiratory chain, 49-KD subunit , complex I 49kDa subunit , mitochondrial complex I subunit NDUFS2

GENE ID SPECIES
226646 Mus musculus
289218 Rattus norvegicus
4720 Homo sapiens
478981 Canis lupus familiaris
100156075 Sus scrofa
327697 Bos taurus
747334 Pan troglodytes
100857596 Gallus gallus
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