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NDUFV1 Products

(NADH Dehydrogenase (Ubiquinone) Flavoprotein 1, 51kDa (NDUFV1))

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The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I\; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction\; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009].

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Featured NDUFV1 Categories

NDUFV1 Antibodies

High quality antibodies with extensive validation data.

NDUFV1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NDUFV1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (1)
  • (6)
Cat. No. ABIN518257
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (5)
Cat. No. ABIN2855323
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7160945
Quantity 100 μL
Datasheet Datasheet

Recommended NDUFV1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6231515
Quantity 96 tests
Datasheet Datasheet

Recommended NDUFV1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312298
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312297
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3084463
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our NDUFV1 products

Jacquemin, Margiotta, Kasahara, Bassoy, Walch, Thiery, Lieberman, Martinvalet: "Granzyme B-induced mitochondrial ROS are required for apoptosis." in: Cell death and differentiation, Vol. 22, Issue 5, pp. 862-74, (2015) (PubMed).

Morán, Rivera, Sánchez-Aragó, Blázquez, Merinero, Ugalde, Arenas, Cuezva, Martín: "Mitochondrial bioenergetics and dynamics interplay in complex I-deficient fibroblasts." in: Biochimica et biophysica acta, Vol. 1802, Issue 5, pp. 443-53, (2010) (PubMed).

Sheftel, Stehling, Pierik, Netz, Kerscher, Elsässer, Wittig, Balk, Brandt, Lill: "Human ind1, an iron-sulfur cluster assembly factor for respiratory complex I." in: Molecular and cellular biology, Vol. 29, Issue 22, pp. 6059-73, (2009) (PubMed).

Saito, Kawamoto, Kamatani: "Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects." in: Journal of human genetics, Vol. 54, Issue 6, pp. 317-23, (2009) (PubMed).

Starr, Shiels, Harris, Pattie, Pearce, Relton, Deary: "Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey." in: Mechanisms of ageing and development, Vol. 129, Issue 12, pp. 745-51, (2008) (PubMed).

Synonyms and alternative names related to NDUFV1

NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (LOC408367), NADH:ubiquinone oxidoreductase core subunit V1 (NDUFV1), NADH:ubiquinone oxidoreductase core subunit V1 (ndufv1), NADH dehydrogenase ubiquinone flavoprotein 1 (ndufv1), NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa (Ndufv1), NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (LOC100179486), NADH dehydrogenase (ubiquinone) flavoprotein 1 (ndufv1), NADH dehydrogenase (ubiquinone) flavoprotein 1 (Ndufv1), NADH:ubiquinone oxidoreductase core subunit V1 (Ndufv1), NADH:ubiquinone oxidoreductase core subunit V1 L homeolog (ndufv1.L), CI-51K, CI-51kD, CI51KD, DDBDRAFT_0188174, DDBDRAFT_0191420, DDB_0188174, DDB_0191420, GB17095, uqor1, UQOR1, wu:fc01f01, wu:fc12f12, zgc:86620

Protein level used designations for NDUFV1

  • NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
  • NADH dehydrogenase ubiquinone flavoprotein 1
  • NADH-ubiquinone oxidoreductase
  • ubiquinone oxidoreductase
  • OXPHOS complex I 51 kDa subunit
  • NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
  • NADH dehydrogenase flavoprotein 1; 24 kDa (FP)
  • NADH-ubiquinone oxidoreductase 51 kDa subunit
  • complex I-51kD
  • complex I 51 kda subunit
  • complex I 51kDa subunit
  • complex I, mitochondrial respiratory chain
  • mitochondrial NADH dehydrogenase ubiquinone flavoprotein 1
  • mitochondrial NADH:ubiquinone oxidoreductase 51 kda subunit
  • CI-51kD
  • NADH dehydrogenase flavoprotein 1
  • NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial
  • mitochondrial complex I subunit NDUFV1
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