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anti-NADPH Oxidase 4 (NOX4) Antibodies

NOX4 encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. Additionally we are shipping NADPH Oxidase 4 Kits (16) and NADPH Oxidase 4 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NOX4 50507 Q9NPH5
NOX4 50490 Q9JHI8
NOX4 85431 Q924V1
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Top anti-NADPH Oxidase 4 Antibodies at antibodies-online.com

Showing 10 out of 120 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB NOX4 Antibody (N-term) (ABIN657946) western blot analysis in CEM cell ... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Dog Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-Nox4/... Mouse muscle lysates probed with Rabbit Anti-NADPH oxidase 4 Polyclona... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Mouse Rabbit Un-conjugated IHC, WB Immunohistochemistry of paraffin-embedded human kidney using NOX4 anti... Western blot analysis of extracts of various cell lines, using NOX4 an... 100 μL Log in to see 9 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-NADPH oxidase 4 antibody, IHC(P) IHC(P): Rat Kidney Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Cow Rabbit Un-conjugated WB Western blot analysis of NOX4 expression in JAR (A), Jurkat (B), SP2/0... 200 μL Log in to see 9 Days
$487.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human kidney labeled with Anti-NO... Formalin-fixed and paraffin embedded rat brain labeled with Anti-NOX4/... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$419.83
Details
Mouse Rabbit Un-conjugated IHC (p)   100 μg Log in to see 8 to 10 Days
$463.83
Details

NOX4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,

Mouse (Murine) , , , ,

Rat (Rattus) , , , ,

Top referenced anti-NADPH Oxidase 4 Antibodies

  1. Human Polyclonal NOX4 Primary Antibody for IHC (p), WB - ABIN657946 : Manea, Tanase, Raicu, Simionescu: Transcriptional regulation of NADPH oxidase isoforms, Nox1 and Nox4, by nuclear factor-kappaB in human aortic smooth muscle cells. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 3 references for ABIN657946

  2. Mouse (Murine) Polyclonal NOX4 Primary Antibody for IHC, WB - ABIN3023201 : Wingler, Wünsch, Kreutz, Rothermund, Paul, Schmidt: Upregulation of the vascular NAD(P)H-oxidase isoforms Nox1 and Nox4 by the renin-angiotensin system in vitro and in vivo. in Free radical biology & medicine 2001 (PubMed)

  3. Dog (Canine) Polyclonal NOX4 Primary Antibody for IF (p), IHC (p) - ABIN737526 : Khan, Byer, Khan: Exposure of Madin-Darby canine kidney (MDCK) cells to oxalate and calcium oxalate crystals activates nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase. in Urology 2014 (PubMed)

More Antibodies against NADPH Oxidase 4 Interaction Partners

Human NADPH Oxidase 4 (NOX4) interaction partners

  1. Nox4 is a positive transcriptional regulator of cystathionine-gamma-lyase (show CTH Antibodies) in endothelial cells.

  2. An endogenous NOX4 forms macromolecular complexes with calnexin (show CANX Antibodies), which are needed for the proper maturation, processing, and function of NOX4 in the endoplasmic reticulum.

  3. IFNgamma induces oxidative stress, DNA damage and tumor cell senescence via TGFbeta/SMAD signaling-dependent induction of Nox4 and suppression of ANT2

  4. Nox4 knockout (Nox4(-/-)) murine hematopoietic progenitor cells were refractory to FLT3ITD-mediated transformation in vitro

  5. The reactive oxygen species-generating NADPH oxidase-4 (Nox4) is induced downstream of ATF4 (show ATF4 Antibodies), binds to a PP1 (show PPA1 Antibodies)-targeting subunit GADD34 (show PPP1R15A Antibodies) at the endoplasmic reticulum, and inhibits PP1 (show PPA1 Antibodies) activity to increase eIF2alpha (show EIF2A Antibodies) phosphorylation and ATF4 (show ATF4 Antibodies) levels.

  6. H2O2-forming NOX4, unlike the superoxide-forming NOX1 (show NOX1 Antibodies), can act as a negative modulator of inflammation and remodeling and convey atheroprotection.

  7. results demonstrate that in VSMCs mechanical stimulation activates cofilin (show CFL1 Antibodies) by a Nox4-dependent mechanism and that this pathway is required for cytoskeleton reorganization and cell reorientation

  8. our results indicate that Nox4-mediated ROS (show ROS1 Antibodies), at least in part, transmit cell survival signals and their depletion leads to apoptosis, thus highlighting the Nox4-ROS (show ROS1 Antibodies)-AKT (show AKT1 Antibodies) signaling pathway as a potential therapeutic target for MPM treatment.

  9. High glucose generated an increase in NADPH oxidase (show NOX1 Antibodies) activity and expression in human vascular smooth muscle cells. Sequence analysis of human Nox1 (show NOX1 Antibodies), Nox4, and Nox5 (show NOX5 Antibodies) gene promoters

  10. results suggest the evaluated NOX4 and CYBA (show CYBA Antibodies) SNPs are not direct genetic determinants of fibrosis in patients with chronic hepatitis C, but nevertheless NOX4 rs3017887 SNP could indirectly influence fibrosis susceptibility due to its inverse association with metabolic syndrome in male patients

Cow (Bovine) NADPH Oxidase 4 (NOX4) interaction partners

  1. Peroxide derived from superoxide generated by Nox4 appears to maintain a basal relaxation in bovine pulmonary arteries under normoxic conditions, which is removed under hypoxia leading to hypoxic pulmonary vasoconstriction.

Rabbit NADPH Oxidase 4 (NOX4) interaction partners

  1. proteasome inhibition completely prevented endoplasmic reticulum stress-induced increase in NADPH oxidase (show NOX1 Antibodies) activity, as well as increases in Nox4 isoform and protein disulfide isomerase (show P4HB Antibodies) mRNA expression

Mouse (Murine) NADPH Oxidase 4 (NOX4) interaction partners

  1. IFNgamma induces oxidative stress, DNA damage and tumor cell senescence via TGFbeta/SMAD signaling-dependent induction of Nox4 and suppression of ANT2

  2. These results indicate that Ang-II (show AGT Antibodies) induces cardiac fibroblast proliferation and migration in part via Nox4/ROS (show ROS1 Antibodies)-dependent IL-18 (show IL18 Antibodies) induction and MMP9 (show MMP9 Antibodies) activation, and may involve AT1 (show SLC33A1 Antibodies)/Nox4 physical association.

  3. H2O2-forming NOX4, unlike the superoxide-forming NOX1 (show NOX1 Antibodies), can act as a negative modulator of inflammation and remodeling and convey atheroprotection.

  4. activated PKCzeta (show PRKCZ Antibodies) phosphorylated p65 (show NFkBP65 Antibodies) rel, which led to increased Nox4 synthesis

  5. ERK1/2 (show MAPK1/3 Antibodies) plays an important role in TGF-beta1 (show TGFB1 Antibodies)-induced mTOR (show FRAP1 Antibodies) activation and translational regulation of Nox4 protein.

  6. Intradermal administration of siHSP47-nanoparticles effectively reduced HSP47 (show SERPINH1 Antibodies) protein expression in skin to normal level.

  7. NOX1 (show NOX1 Antibodies) and NOX4 signaling mediates the pathogenesis of liver fibrosis, including the direct activation of HSC (show FUT1 Antibodies).

  8. Nox4 maintains VEGF (show VEGFA Antibodies) expression and prevents an increase in angiopoietin 1 (show ANGPT1 Antibodies) expression, thereby contributing to angiogenesis in exercise. Nox4 does not influence developmental angiogenesis.

  9. Fluid shear stress regulates PLGF (show PGF Antibodies) expression via NADPH oxidase 4 and reactive oxygen species signaling.

  10. eNOS (show NOS3 Antibodies) plays a key role in the regulation of expression of NOX2 (show CYBB Antibodies) and NOX4 in the lungs exposed to hypoxia.

Pig (Porcine) NADPH Oxidase 4 (NOX4) interaction partners

  1. MRTF down-regulation/inhibition suppresses TGFbeta (show TGFB1 Antibodies)/contact disruption-provoked Nox4 protein and mRNA expression, Nox4 promoter activation, and reactive oxygen species production.

  2. Nox4 NADPH oxidase (show NOX1 Antibodies) mediates oxidative stress and apoptosis caused by TNF-alpha (show TNF Antibodies) in cerebral vascular endothelial cells.

  3. Nox4 NADPH oxidase (show NOX1 Antibodies)-derived reactive oxygen species also initiate a cell survival mechanism by increasing production of carbon monoxide by constitutive heme oxygenase-2 (show HMOX2 Antibodies).

NADPH Oxidase 4 (NOX4) Antigen Profile

Protein Summary

This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with anti-NADPH Oxidase 4 (NOX4) Antibodies

  • NADPH oxidase 4 (NOX4) antibody
  • NADPH oxidase 4 (nox4) antibody
  • NADPH oxidase 4 (PTRG_09562) antibody
  • NADPH oxidase 4 (Nox4) antibody
  • AI648021 antibody
  • KOX antibody
  • KOX-1 antibody
  • NOX4 antibody
  • RENOX antibody

Protein level used designations for anti-NADPH Oxidase 4 (NOX4) Antibodies

NADPH oxidase 4 , predicted NADPH oxidase-4 , kidney oxidase-1 , kidney superoxide-producing NADPH oxidase , renal NAD(P)H-oxidase , KOX-1 , superoxide-generating NADPH oxidase 4 , kox-1

GENE ID SPECIES
419012 Gallus gallus
619226 Ciona intestinalis
705931 Macaca mulatta
735636 Pan troglodytes
6347852 Pyrenophora tritici-repentis Pt-1C-BFP
50507 Homo sapiens
378474 Bos taurus
100034665 Ovis aries
100339697 Oryctolagus cuniculus
50490 Mus musculus
85431 Rattus norvegicus
100523323 Sus scrofa
485144 Canis lupus familiaris
100171782 Pongo abelii
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