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NOX5 is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. Additionally we are shipping NOX5 Proteins (4) and and many more products for this protein.
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REVIEW: recent knowledge of the genetic and enzymatic regulation of NOX5 and the importance of NOX5 in human physiology and pathophysiology.
Rho Kinase ROCK2 (show ROCK2 Antibodies) Mediates Acid-Induced NADPH Oxidase (show NOX1 Antibodies) NOX5-S Expression in Human Esophageal Adenocarcinoma Cells
Nox5-derived ROS (show ROS1 Antibodies) and subsequent depletion of PKCzeta (show PRKCZ Antibodies) and JNK (show MAPK8 Antibodies) inactivation play a critical role in modulating intracellular signaling cascades involved in the proliferation and survival of PCa (show FLVCR1 Antibodies) cells.
High glucose generated an increase in NADPH oxidase (show NOX1 Antibodies) activity and expression in human vascular smooth muscle cells. Sequence analysis of human Nox1 (show NOX1 Antibodies), Nox4 (show NOX4 Antibodies), and Nox5 gene promoters
NOX5-derived reactive oxygen species contribute to apoptosis blockage in ALK (show ALK Antibodies)-positive anaplastic large-cell lymphoma cell lines.
Tissue microarray analysis revealed, for the first time, substantial Nox5 overexpression in several human cancers
Initial findings suggest that glomerular and tubular expression of Nox5 is induced during diabetes and hypertension, respectively. Furthermore, identification of SNPs in distinct human populations suggests a role for either good or ill for this enzyme.
Induction of Nox5 expression in IFNgamma- and oxidized LDL-exposed Mac and the presence of Nox5 in Mac-rich atheroma are indicative of the implication of Nox5 in atherogenesis.
Results show that NOX5 is expressed in human renal proximal tubule cells and to greater extent than the other NOX isoforms in hypertensive than normotensive subjects.
we show here for the first time that two members of the ROS (show ROS1 Antibodies)-generating NADPH oxidase (show NOX1 Antibodies) family (NOXs), NOX4 (show NOX4 Antibodies) and NOX5, are involved in radiation-induced DNA damage.
This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
NADPH oxidase 5