anti-N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2) Antibodies

NAT2 encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Additionally we are shipping NAT2 Proteins (9) and NAT2 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NAT2 116632 P50298
NAT2 10 P11245
NAT2 17961 P50295
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-NAT2 Antibodies at antibodies-online.com

Showing 10 out of 62 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-NAT2 Antibody Titration: 2.5ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of NAT2 Antibody (C-term) in mouse kidney tissue lysates (35ug/lane).NAT2 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of NAT2 expression in transfected 293T cell line by NAT2 monoclonal antibody (M01), clone 3B5. Lane 1: NAT2 transfected lysate(33.5 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of NAT2 Antibody (C-term) (ABIN652275) in mouse kidney tissue lysates (35 µg/lane).NAT2 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma with NAT2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Rabbit Un-conjugated IHC (p), IHC, WB Immunohistochemistry-Paraffin: NAT2 Antibody [NBP1-33751] - Paraffin-embedded A549 xenograft, using antibody at 1:100 dilution. Western Blot: NAT2 Antibody [NBP1-33751] - Sample (30 ug of whole cell lysate) A: A431 B: H1299 12% SDS PAGE; antibody diluted at 1:1000. 0.1 mL Log in to see 7 to 9 Days
$447.56
Details

NAT2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus) , ,


Human , ,
, ,
,
, , , , ,
Mouse (Murine) , ,


, , , , ,

Top referenced anti-NAT2 Antibodies

  1. Human Monoclonal NAT2 Primary Antibody for WB - ABIN393669 : Djordjevic, Carrillo, Ueda, Gervasini, Fukasawa, Suda, Jankovic, Aklillu: N-Acetyltransferase-2 (NAT2) gene polymorphisms and enzyme activity in Serbs: unprecedented high prevalence of rapid acetylators in a White population. in Journal of clinical pharmacology 2011 (PubMed)
    Show all 5 references for 393669

  2. Human Polyclonal NAT2 Primary Antibody for WB - ABIN2781757 : Ricco, Cau, Marchand, Marty, Rodde-Dunet, Fender, Allemand, Corsini: Stent-graft repair for thoracic aortic disease: results of an independent nationwide study in France from 1999 to 2001. in The Journal of thoracic and cardiovascular surgery 2006 (PubMed)

  3. Human Polyclonal NAT2 Primary Antibody for EIA, WB - ABIN453210 : Kim, Kim, Bahn, Kim, Chang, Shin, Kim, Park, Kim, Jang, Song, Kim, Park, Min, Jee: Genetic polymorphisms of drug-metabolizing enzymes and anti-TB drug-induced hepatitis. in Pharmacogenomics 2009 (PubMed)

More Antibodies against NAT2 Interaction Partners

Human N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2) interaction partners

  1. 182 Hungarian bladder cancer cases and 78 cancer-free controls were investigated. It was not possible to establish a particular impact of NAT2 (show SLC38A1 Antibodies)*6A and *7B genotypes (15 cases, 8%, 5 controls, 7%). GSTT1 (show GSTT1 Antibodies) exerted no marked influence on bladder cancer (negative 21% cases vs. 22% controls). The portion of GSTM1 (show GSTM1 Antibodies) negative bladder cancer patients was increased (63% cases vs. 54% controls).

  2. Various antitubercular isoniazid dosing regimens have been proposed for NAT2 (show SLC38A1 Antibodies)-specific immunocompetent and immune-deficient patient populations.

  3. Data suggest that metabolism (and possibly pharmacokinetics) of hypnotic nitrazepam involves liver enzymes AOX1 (aldehyde oxidase 1 (show AOX1 Antibodies)), NAT2 (N-acetyltransferase 2), AADAC (arylacetamide deacetylase (show AADAC Antibodies)), and CYP3A4 (cytochrome P450 3A4 (show CYP3A4 Antibodies)).

  4. The multicolor melting curve assay described in our study is very promising for the efficient determination of NAT2 (show SLC38A1 Antibodies) genotype, and can facilitate the personalized dosing of isoniazid

  5. No significant differences in the acetylator NAT2 (show SLC38A1 Antibodies) haplotype and phenotype distributions were found between Native American populations practicing farming and/or herding and those practicing hunting and gathering.

  6. In any patient who may receive INH and happens to be NAT2 (show SLC38A1 Antibodies) slow acetylator type, NAT2 (show SLC38A1 Antibodies) genotype by covert action may influence the clinical response of above drugs.

  7. Homozygous mutant allele of NAT2 (show SLC38A1 Antibodies) gene at 481site may act as a predisposing factor for phenytoin intoxication among tuberculous meningitis or tuberculoma patients having seizures.

  8. In the present study, we report that the most common NAT2 (show SLC38A1 Antibodies) haplotype in the Korean population (TACGAGG; frequency = 47.6%) is associated with a low expression level of NAT2 (show SLC38A1 Antibodies). We failed to find a significant relationship between rs4646241 and enzyme expression level. Haplotypes of Caucasian and African populations were markedly different from those of the Korean population.

  9. We genotyped four selected variants of the NAT2 (show SLC38A1 Antibodies) gene (NAT2 (show SLC38A1 Antibodies)*5, NAT2 (show SLC38A1 Antibodies)*6, NAT2 (show SLC38A1 Antibodies)*7, and NAT2 (show SLC38A1 Antibodies)*14) by Sanger sequencing. The majority of patients had NAT2 (show SLC38A1 Antibodies) genotypes previously described as slow acetylators including NAT2 (show SLC38A1 Antibodies)*5/*5, NAT2 (show SLC38A1 Antibodies)*5/*6, NAT2 (show SLC38A1 Antibodies)*6/*6, and NAT2 (show SLC38A1 Antibodies)*6/*14 (78%) and none were genotyped as rapid acetylators. Controls were slow, intermediate, and rapid acetylators with frequencies of 72.39%, 21.48%, and 6.13%, respectively

  10. this study confirms the significance of the association between slow-acetylator NAT2 (show SLC38A1 Antibodies) variants and susceptibility to AT-DILI in an Indonesian population.

Mouse (Murine) N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2) interaction partners

  1. Overexpression of X-box binding protein-1 (show XBP1 Antibodies) led to a marked increase in luciferase activity in P19 (show CDKN2D Antibodies) cells transfected with the Slc38a1 (show SLC38A1 Antibodies) reporter plasmid. These results suggest that theanine accelerates cellular proliferation and subsequent neuronal specification through a mechanism relevant to upregulation of Slc38a1 (show SLC38A1 Antibodies) gene in undifferentiated neural progenitor cells

  2. We found that MeCP2 (show MECP2 PLURAL_@4252@) acts as a microglia-specific transcriptional repressor of

  3. It was concluded that an acute colonic inflammation impairs the expression and function of NAT2 enzyme, thereby diminishing the capacity for 5-aminosalisylic acid metabolism by colonic mucosa.

  4. GlnT (show SLC38A1 Antibodies) would promote both proliferation and neuronal differentiation through a mechanism relevant to the upregulation of particular proneural genes in undifferentiated P19 (show CDKN2D Antibodies) cells.

  5. Inner hair cells express glutamine transporter SLC38A1 (show SLC38A1 Antibodies).

  6. Hyperhomocysteinemia-induced decrease of peroxynitrite level is associated with an increase of hepatic Nat2 isoform activity with a reversal effect of wine polyphenol extract supplementation.

  7. In this study, the in vivo endothelial membrane localization of the sodium-dependent glutamine (show GFPT1 Antibodies) transporters Snat3 (Slc38a3 (show SLC38A3 Antibodies)) and Snat1 (Slc38a1 (show SLC38A1 Antibodies)) was investigated in the mouse brain microvasculature.

  8. Mouse NAT2 is likely to influence epigenetic gene control, particularly of its own locus, and this is consistent with recent evidence associating aberrant mouse Nat2/human NAT1 (show EIF4G2 Antibodies) gene expression with certain developmental malformations and cancers.

  9. Nat2 knockout mouse line demonstrates that different Nat2 isoforms have distinct functions with no compensatory expression, in Nat2 knockout animals, of the other isoforms.

  10. Variation in capacity for acetylation of 4ABP and PABA resulting from endogenous murine NAT2 alleles is insufficient to affect 4ABP genotoxicity in liver.

Rhesus Monkey N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2) interaction partners

  1. The study is the first to thoroughly characterize the properties of a polymorphic NAT isoenzyme in a non-human primate model.

NAT2 Antigen Profile

Protein Summary

This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2).

Gene names and symbols associated with NAT2

  • N-acetyltransferase 2 (Nat2) antibody
  • N-acetyltransferase 2 (arylamine N-acetyltransferase) (NAT2) antibody
  • N-acetyltransferase 2 (arylamine N-acetyltransferase) (Nat2) antibody
  • solute carrier family 38, member 1 (Slc38a1) antibody
  • AA408026 antibody
  • AA409865 antibody
  • AAC2 antibody
  • AL022800 antibody
  • AT-2 antibody
  • AT-B/AT-II antibody
  • AT-II antibody
  • AT2 antibody
  • AU015942 antibody
  • AV377607 antibody
  • NAT antibody
  • NAT-2 antibody
  • NAT2 antibody
  • Nat2a antibody
  • PNAT antibody

Protein level used designations for NAT2

AT-2 , N-Acetyltransferase-2 (arylamine N-acetyltransferase) , N-acetyltransferase 2 (arylamine N-acetyltransferase) , N-acetyltransferase type 2 , NAT-2 , arylamide acetylase 2 , arylamine N-acetyltransferase 2 , N-acetyl transferase 2 , PNAT , lambda R-1 , polymorphic arylamine N-acetyltransferase , Arylamide acetylase 2 , NAT2 15 , Polymorphic arylamine N-acetyltransferase , acetyltransferase , arylamine N-acetyltransferase-2 , MNat2 , N-system amino acid transporter 2 , amino acid transporter A1 , sodium-coupled neutral amino acid transporter 1 , system A amino acid transporter 1 , system N amino acid transporter 1

GENE ID SPECIES
116632 Rattus norvegicus
10 Homo sapiens
17961 Mus musculus
100008974 Oryctolagus cuniculus
101840555 Mesocricetus auratus
704357 Macaca mulatta
105727 Mus musculus
Selected quality suppliers for anti-NAT2 (NAT2) Antibodies
Did you look for something else?