N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2) ELISA Kits

NAT2 encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Additionally we are shipping NAT2 Antibodies (63) and NAT2 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
NAT2 116632 P50298
Anti-Human NAT2 NAT2 10 P11245
Anti-Mouse NAT2 NAT2 17961 P50295
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Top NAT2 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Rat 0.218 ng/mL 0.62-40 ng/mL 96 Tests Log in to see 13 to 16 Days
$640.00
Details

More ELISA Kits for NAT2 Interaction Partners

Human N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2) interaction partners

  1. Our findings suggested that NAT2 (show SLC38A1 ELISA Kits) gene polymorphism rs1799931 was associated with decreased risk of acute myeloid leukemia (show BCL11A ELISA Kits) and was likely to be a protective factor against acute myeloid leukemia (show BCL11A ELISA Kits) development.

  2. Study reestablished the association between NAT2 (show SLC38A1 ELISA Kits) SA and isoniazid-induced liver injury in a Singaporean population and demonstrated its clinical validity in prediction of isoniazid-induced liver injury.

  3. In non-syndromic cleft lip with or without cleft palate, we found a significant association between the EGF61 (rs4444903) and NSCL (show NHLH1 ELISA Kits)/P (P = .01) genes. Conversely, NAT2 (show SLC38A1 ELISA Kits) (rs1799929) was not significantly different between the cases and the control group

  4. 182 Hungarian bladder cancer cases and 78 cancer-free controls were investigated. It was not possible to establish a particular impact of NAT2 (show SLC38A1 ELISA Kits)*6A and *7B genotypes (15 cases, 8%, 5 controls, 7%). GSTT1 (show GSTT1 ELISA Kits) exerted no marked influence on bladder cancer (negative 21% cases vs. 22% controls). The portion of GSTM1 (show GSTM1 ELISA Kits) negative bladder cancer patients was increased (63% cases vs. 54% controls).

  5. Various antitubercular isoniazid dosing regimens have been proposed for NAT2 (show SLC38A1 ELISA Kits)-specific immunocompetent and immune-deficient patient populations.

  6. Data suggest that metabolism (and possibly pharmacokinetics) of hypnotic nitrazepam involves liver enzymes AOX1 (aldehyde oxidase 1 (show AOX1 ELISA Kits)), NAT2 (N-acetyltransferase 2), AADAC (arylacetamide deacetylase (show AADAC ELISA Kits)), and CYP3A4 (cytochrome P450 3A4 (show CYP3A4 ELISA Kits)).

  7. The multicolor melting curve assay described in our study is very promising for the efficient determination of NAT2 (show SLC38A1 ELISA Kits) genotype, and can facilitate the personalized dosing of isoniazid

  8. No significant differences in the acetylator NAT2 (show SLC38A1 ELISA Kits) haplotype and phenotype distributions were found between Native American populations practicing farming and/or herding and those practicing hunting and gathering.

  9. In any patient who may receive INH and happens to be NAT2 (show SLC38A1 ELISA Kits) slow acetylator type, NAT2 (show SLC38A1 ELISA Kits) genotype by covert action may influence the clinical response of above drugs.

  10. Homozygous mutant allele of NAT2 (show SLC38A1 ELISA Kits) gene at 481site may act as a predisposing factor for phenytoin intoxication among tuberculous meningitis or tuberculoma patients having seizures.

Mouse (Murine) N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2) interaction partners

  1. Overexpression of X-box binding protein-1 (show XBP1 ELISA Kits) led to a marked increase in luciferase activity in P19 (show CDKN2D ELISA Kits) cells transfected with the Slc38a1 (show SLC38A1 ELISA Kits) reporter plasmid. These results suggest that theanine accelerates cellular proliferation and subsequent neuronal specification through a mechanism relevant to upregulation of Slc38a1 (show SLC38A1 ELISA Kits) gene in undifferentiated neural progenitor cells

  2. We found that MeCP2 acts as a microglia-specific transcriptional repressor of

  3. It was concluded that an acute colonic inflammation impairs the expression and function of NAT2 enzyme, thereby diminishing the capacity for 5-aminosalisylic acid metabolism by colonic mucosa.

  4. GlnT would promote both proliferation and neuronal differentiation through a mechanism relevant to the upregulation of particular proneural genes in undifferentiated P19 cells.

  5. Inner hair cells express glutamine transporter SLC38A1 (show SLC38A1 ELISA Kits).

  6. Hyperhomocysteinemia-induced decrease of peroxynitrite level is associated with an increase of hepatic Nat2 isoform activity with a reversal effect of wine polyphenol extract supplementation.

  7. In this study, the in vivo endothelial membrane localization of the sodium-dependent glutamine (show GFPT1 ELISA Kits) transporters Snat3 (Slc38a3 (show SLC38A3 ELISA Kits)) and Snat1 (Slc38a1 (show SLC38A1 ELISA Kits)) was investigated in the mouse brain microvasculature.

  8. Mouse NAT2 is likely to influence epigenetic gene control, particularly of its own locus, and this is consistent with recent evidence associating aberrant mouse Nat2/human NAT1 (show EIF4G2 ELISA Kits) gene expression with certain developmental malformations and cancers.

  9. Nat2 knockout mouse line demonstrates that different Nat2 isoforms have distinct functions with no compensatory expression, in Nat2 knockout animals, of the other isoforms.

  10. Variation in capacity for acetylation of 4ABP and PABA resulting from endogenous murine NAT2 alleles is insufficient to affect 4ABP genotoxicity in liver.

Rhesus Monkey N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2) interaction partners

  1. The study is the first to thoroughly characterize the properties of a polymorphic NAT isoenzyme in a non-human primate model.

NAT2 Antigen Profile

Antigen Summary

This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2).

Gene names and symbols associated with NAT2

  • N-acetyltransferase 2 (Nat2) antibody
  • N-acetyltransferase 2 (arylamine N-acetyltransferase) (NAT2) antibody
  • N-acetyltransferase 2 (arylamine N-acetyltransferase) (Nat2) antibody
  • solute carrier family 38, member 1 (Slc38a1) antibody
  • AA408026 antibody
  • AA409865 antibody
  • AAC2 antibody
  • AL022800 antibody
  • AT-2 antibody
  • AT-B/AT-II antibody
  • AT-II antibody
  • AT2 antibody
  • AU015942 antibody
  • AV377607 antibody
  • NAT antibody
  • NAT-2 antibody
  • NAT2 antibody
  • Nat2a antibody
  • PNAT antibody

Protein level used designations for NAT2

AT-2 , N-Acetyltransferase-2 (arylamine N-acetyltransferase) , N-acetyltransferase 2 (arylamine N-acetyltransferase) , N-acetyltransferase type 2 , NAT-2 , arylamide acetylase 2 , arylamine N-acetyltransferase 2 , N-acetyl transferase 2 , PNAT , lambda R-1 , polymorphic arylamine N-acetyltransferase , Arylamide acetylase 2 , NAT2 15 , Polymorphic arylamine N-acetyltransferase , acetyltransferase , arylamine N-acetyltransferase-2 , MNat2 , N-system amino acid transporter 2 , amino acid transporter A1 , sodium-coupled neutral amino acid transporter 1 , system A amino acid transporter 1 , system N amino acid transporter 1

GENE ID SPECIES
116632 Rattus norvegicus
10 Homo sapiens
17961 Mus musculus
100008974 Oryctolagus cuniculus
101840555 Mesocricetus auratus
704357 Macaca mulatta
105727 Mus musculus
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