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NDRG Family Member 2 Proteins (NDRG2)

NDRG2 is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. Additionally we are shipping NDRG2 Antibodies (89) and NDRG2 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NDRG2 29811 Q9QYG0
NDRG2 57447 Q9UN36
NDRG2 171114 Q8VBU2
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Top NDRG2 Proteins at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days
$2,970.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,970.00
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,970.00
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,982.83
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,982.83
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$3,008.50
Details

NDRG2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus)

Top referenced NDRG2 Proteins

  1. Human NDRG2 Protein expressed in Escherichia coli (E. coli) - ABIN1098670 : Deng, Yao, Chau, Ng, Peng, Liu, Au, Wang, Li, Ji, Han, Nie, Li, Kung, Leung, Lin: N-Myc downstream-regulated gene 2 (NDRG2) inhibits glioblastoma cell proliferation. in International journal of cancer. Journal international du cancer 2003 (PubMed)
    Show all 2 references for ABIN1098670

More Proteins for NDRG Family Member 2 (NDRG2) Interaction Partners

Mouse (Murine) NDRG Family Member 2 (NDRG2) interaction partners

  1. Using double knockout of NDR1 (show STK38 Proteins) and 2 shows that NDRs acted downstream of MST1 (show MST1 Proteins) to mediate the egress of mature thymocytes from the thymus, as well as the interstitial migration of naive T cells within popliteal lymph nodes.

  2. The expression level of NDRG2 has a causal influence on mood-related phenotypes.

  3. Ndr1 (show STK38 Proteins)/2-double null embryos show defects in somitogenesis and cardiac looping, which reveals their essential functions and shows that the NDR (show STK38 Proteins) kinases are critically required during the early phase of organogenesis

  4. Taken together, our results suggest that the expression of NDRG2 potentially inhibits osteoclast differentiation and plays a role in modulating the signal transduction pathway responsible for osteoclastogenesis.

  5. NDRG2 is associated with decidualization during early pregnancy.

  6. NDRG2 accumulated in skeletal muscle and myoblasts in the absence of TRIM32 (show TRIM32 Proteins). NDRG2 overexpression in myoblasts led to reduced cell proliferation and delayed cell cycle withdrawal during differentiation.

  7. Electroacupuncture administration can alleviate reference memory deficits and suppress N-myc downstream-regulated gene 2 upregulation in an AD transgenic mouse model

  8. Rassf5 (show RASSF5 Proteins) and Ndr1 (show STK38 Proteins) or Ndr2 (show STK38L Proteins) kinases regulate neuronal polarity through Par3 (show F2RL2 Proteins) phosphorylation.

  9. Ndrg2 plays a key role in reactive astrogliosis after cortical stab injury through a mechanism involving the positive regulation of IL-6 (show IL6 Proteins)/STAT3 (show STAT3 Proteins) signaling

  10. Ndr2 (show STK38L Proteins) controls beta1-integrin phosphorylation and trafficking crucial for neurite growth.

Human NDRG Family Member 2 (NDRG2) interaction partners

  1. NDRG2 overexpression enhanced sodium/iodide symporter level in thyroid tumor cells and increased their iodine uptake in vitro.

  2. Epigenetic silencing of NDRG2 promotes colorectal cancer proliferation and invasion.

  3. miR (show MLXIP Proteins)-301a/b-NDRG2 might be an important axis modulating autophagy and viability of prostate cancer cells under hypoxia.

  4. Loss of NDRG2 induced the expression of matrix metalloproteinase-19 (MMP-19 (show MMP19 Proteins)), which regulated the expression of Slug (show SNAI2 Proteins) at the transcriptional level in the epithelial-mesenchymal transition of gallbladder carcinoma cells.

  5. The forced expression of NDRG2 in ATL cells down-regulates not only the canonical pathway by inhibiting AKT (show AKT1 Proteins) signaling but also the non-canonical pathway by inducing NF-kappaB (show NFKB1 Proteins)-inducing kinase (NIK (show MAP3K14 Proteins)) dephosphorylation via the recruitment of PP2A (show PPP2R4 Proteins)

  6. NDRG2 functions as an essential regulator in glycolysis and glutaminolysis via repression of c-Myc (show MYC Proteins), and acts as a suppressor of carcinogenesis.

  7. This review summarizes the distribution and subcellular localization of NDRG2 in brain tissues, highlights the physiological actions of NDRG2 in the nervous system, and discusses the roles of NDRG2 during the occurrence of nervous system disease. [review]

  8. NDRG2 suppresses the proliferation of human bladder cancer cells via induction of oncosis.

  9. Authors found that H. pylori silenced Ndrg2 by activating the NF-kappaB (show NFKB1 Proteins) pathway and up-regulating DNMT3b (show DNMT3B Proteins), promoting gastric cancer progression. Findings uncover a previously unrecognized role for H. pylori infection in gastric cancer.

  10. Patients with high ITLN1 (show ITLN1 Proteins) or NDRG2 expression had greater survival probability.

NDRG2 Protein Profile

Protein Summary

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Gene names and symbols associated with NDRG Family Member 2 Proteins (NDRG2)

  • NDRG family member 2 (ndrg2)
  • NDRG family member 2 (NDRG2)
  • N-myc downstream regulated gene 2 (Ndrg2)
  • N-myc downstream regulated gene 2 (ndrg2)
  • NDRG family member 2 (Ndrg2)
  • NDRG2 (LOC780431)
  • AI182517 protein
  • AU040374 protein
  • im:6909381 protein
  • Ndr2 protein
  • NDRG2 protein
  • si:dkey-88n24.1 protein
  • SYLD protein
  • zgc:101847 protein

Protein level used designations for NDRG Family Member 2 Proteins (NDRG2)

protein NDRG2 , NDRG family member 2 , N-myc downstream-regulated gene 2 , N-myc downstream regulated 2 , N-myc downstream-regulated gene 2 protein , protein Ndr2 , N-myc downstream regulator 2 , NDR1-related protein NDR2 , cytoplasmic protein Ndr1 , syld709613 protein , N-myc downstream regulated gene 2 , NDRG1-related protein , antidepressant-related protein ADRG123 , N-Myc downstream regulated gene 2

GENE ID SPECIES
493281 Xenopus (Silurana) tropicalis
706990 Macaca mulatta
100351595 Oryctolagus cuniculus
29811 Mus musculus
494050 Danio rerio
380081 Xenopus laevis
57447 Homo sapiens
609390 Canis lupus familiaris
515063 Bos taurus
171114 Rattus norvegicus
100174656 Pongo abelii
100499579 Pan troglodytes
780431 Sus scrofa
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