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NDRG Family Member 4 Proteins (NDRG4)

NDRG4 is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. Additionally we are shipping NDRG Family Member 4 Antibodies (71) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NDRG4 234593 Q8BTG7
NDRG4 65009 Q9ULP0
Rat NDRG4 NDRG4 64457  
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Top NDRG Family Member 4 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

NDRG4 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for NDRG Family Member 4 (NDRG4) Interaction Partners

Mouse (Murine) NDRG Family Member 4 (NDRG4) interaction partners

  1. up-regulation of NDRG4 aggravates myocardial ischemia/reperfusion injury by inhibiting activation of the RISK pathway

  2. Availability of the conditional allele for Ndrg4 should facilitate further detailed analyses of the potential roles of Ndrg4 in gut (show GUSB Proteins) development, nervous system and immune system.

  3. Bves (show BVES Proteins) and NDRG4 regulate directional epicardial cell migration through autocrine extracellular matrix deposition.

  4. NDRG4 contributes to the maintenance of intracerebral BDNF (show BDNF Proteins) levels within the normal range

  5. NDRG4 is required for cell cycle progression and survival, thereby diverging in function from its tumor suppressive family member NDRG2 (show NDRG2 Proteins) in astrocytes and GBM cells

Human NDRG Family Member 4 (NDRG4) interaction partners

  1. These findings bring novel insight to the roles of NDRG4 in meningioma progression

  2. Two downregulated genes, NDRG4 and GINS3 (show GINS3 Proteins), have been located in a genomic interval associated with cardiac repolarization in published GWASs and zebra fish knockout models

  3. A homozygous variant in NDRG4 may be the causative variant of the autosomal recessive form of infantile myofibromatosis.

  4. summarizes the current research on NDRG3 and NDRG4,including the molecular structure, cellular and tissue distribution, biological function, and function in cancer.

  5. expression of NDRG4 is downregulated in human gliomas. The glioma patients with lower NDRG4 expression have a poor prognosis.

  6. NDRG4 is involved in modulating cell proliferation, invasion, migration and angiogenesis in meningioma, and may play a valuable role as a molecular target in its treatment

  7. Over expression of NDRG4 inhibited proliferation of GBM cells.

  8. smap8 is involved in the regulation of mitogenic signalling in vascular smooth muscle cells, possibly in response to a homocysteine-induced injury [SMAP8]

  9. NDRG4 is a candidate tumor suppressor gene in colorectal cancer whose expression is frequently inactivated by promoter methylation.

  10. NDRG4 is required for cell cycle progression and survival, thereby diverging in function from its tumor suppressive family member NDRG2 (show NDRG2 Proteins) in astrocytes and GBM cells

NDRG Family Member 4 (NDRG4) Protein Profile

Protein Summary

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that is required for cell cycle progression and survival in primary astrocytes and may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells. Alternative splicing results in multiple transcripts encoding different isoforms.

Gene names and symbols associated with NDRG Family Member 4 Proteins (NDRG4)

  • NDRG family member 4 (NDRG4)
  • NDRG family member 4 (ndrg4-a)
  • NDRG family member 3 (ndrg3)
  • N-myc downstream regulated gene 4 (Ndrg4)
  • NDRG family member 4 (Ndrg4)
  • Bdm1 protein
  • D8Bwg1337e protein
  • Ndr1-rs protein
  • Ndr4 protein
  • ndrg3 protein
  • NDRG4 protein
  • R74996 protein
  • SMAP-8 protein
  • smap8 protein

Protein level used designations for NDRG Family Member 4 Proteins (NDRG4)

protein NDRG3 , NDRG family member 4 , protein NDRG4 , protein NDRG4-like , N-myc downstream regulated 1, related sequence , N-myc downstream-regulated gene 4 protein , protein Ndr4 , brain development-related molecule 1 , smooth muscle-associated protein 8 , vascular smooth muscle cell-associated protein 8 , N-myc downstream regulated 4 , N-myc downstream regulated gene 4 , development-related protein

GENE ID SPECIES
100052493 Equus caballus
443853 Xenopus laevis
448335 Xenopus (Silurana) tropicalis
454376 Pan troglodytes
768618 Gallus gallus
100443450 Pongo abelii
100590511 Nomascus leucogenys
234593 Mus musculus
65009 Homo sapiens
64457 Rattus norvegicus
611099 Canis lupus familiaris
100626374 Sus scrofa
515033 Bos taurus
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