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NDRG4 is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. Additionally we are shipping NDRG Family Member 4 Antibodies (72) and NDRG Family Member 4 Proteins (6) and many more products for this protein.
NDRG4 might play an important role during early pregnancy.
up-regulation of NDRG4 aggravates myocardial ischemia/reperfusion injury by inhibiting activation of the RISK pathway
Availability of the conditional allele for Ndrg4 should facilitate further detailed analyses of the potential roles of Ndrg4 in gut (show GUSB ELISA Kits) development, nervous system and immune system.
Bves (show BVES ELISA Kits) and NDRG4 regulate directional epicardial cell migration through autocrine extracellular matrix deposition.
NDRG4 contributes to the maintenance of intracerebral BDNF (show BDNF ELISA Kits) levels within the normal range
NDRG4 is required for cell cycle progression and survival, thereby diverging in function from its tumor suppressive family member NDRG2 (show NDRG2 ELISA Kits) in astrocytes and GBM cells
NDRG4 - the biomarker of a currently in-use multi-target stool DNA test was commonly expressed in tumor tissue specimens, independent of Fecal Immunochemical Test result.
Data indicate that patients with tumor of reduced NDRG family member 4 protein (NDRG4) mRNA level had unfavorable disease-free and overall survival.
Study shows that NDRG4 was significantly up-regulated in glioblastomas (GBM) and seems to play a role in GBM prognosis. These results indicate that NDRG4 gene in MGMT (show MGMT ELISA Kits)-methylated cells is a putative tumor-suppressor gene and an oncogene (show RAB1A ELISA Kits) in cells with unmethylated MGMT (show MGMT ELISA Kits).
These findings bring novel insight to the roles of NDRG4 in meningioma progression
Two downregulated genes, NDRG4 and GINS3 (show GINS3 ELISA Kits), have been located in a genomic interval associated with cardiac repolarization in published GWASs and zebra fish knockout models
A homozygous variant in NDRG4 may be the causative variant of the autosomal recessive form of infantile myofibromatosis.
summarizes the current research on NDRG3 and NDRG4,including the molecular structure, cellular and tissue distribution, biological function, and function in cancer.
expression of NDRG4 is downregulated in human gliomas. The glioma patients with lower NDRG4 expression have a poor prognosis.
NDRG4 is involved in modulating cell proliferation, invasion, migration and angiogenesis in meningioma, and may play a valuable role as a molecular target in its treatment
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that is required for cell cycle progression and survival in primary astrocytes and may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells. Alternative splicing results in multiple transcripts encoding different isoforms.
, NDRG family member 4
, protein NDRG4
, protein NDRG4-like
, N-myc downstream regulated 1, related sequence
, N-myc downstream-regulated gene 4 protein
, protein Ndr4
, brain development-related molecule 1
, smooth muscle-associated protein 8
, vascular smooth muscle cell-associated protein 8
, N-myc downstream regulated 4
, N-myc downstream regulated gene 4
, development-related protein